Excerpts

Furthermore, our assumption that asbestos consumption in earlier periods was equal to that estimated for 1946 has to be considered a limitation of the study, according to the plausibility of an increasing trend between 1920–1946, although including a linear increasing trend for the period 1881–1946 does not significantly affect model forecasts ( Figure S2 , model A4).

While our study is not able to close this gap in the knowledge, the RS showed a highly significant difference between the HRG and the LRG in the TP53 mutated samples.

Although there are known characteristics of EOGC, there are some inconsistent data between studies, i.e., some studies reported a female predominance [ 23 ], while in others there was an increasing trend for males or without a significant difference between genders [ 25 , 26 ].

However, family history of other neoplasms showed a trend towards statistical significance with p = 0.057. 4.

In addition, both genes showed similar trends in different stages, with a clear trend of increasing PDL1 scores in stage IV and stage II–III, and an increasing trend of ACSS2 scores in stage I and stage II–III ( Figure 5 g,j).

The results of this study showed a decreasing trend of immune checkpoint expression (PD-1, PD-L1, PD-L2, TIM-3, LAG-3 and galectin-9) in two of the three cell lines when treated with cisplatin, oxaliplatin or pemetrexed [ 128 ].

Findings suggest (1) a positive trend between the diagnostic performance and radiologist’s experience, (2) DNN yielded equivalent or even higher performance in comparison with senior radiologists, and (3) low image resolution reduced the model performance in predicting the risks of GGNs.

Reports on how much additional improvement in EOR achieved with 5-ALA vary, though since 2006 there has been an increasing trend of higher gross total resections demonstrating growing familiarity with the technique.

However, strikingly, analysis of a limited number of these specimens available to us revealed a clear trend suggesting a positive correlation between upregulation of GLO1 in normal tissue adjacent to HGPIN lesions displaying strong GLO1 expression ( Figure 2 C).

The interaction test between CD8 status and tamoxifen treatment for relapse-free interval showed a trend (P interaction = 0.082).

The CD8 + cells showed a trend toward increased number in the MNU-treated group (423 ± 35 cells/mm 2 ) than in the placebo group (142 ± 13 cells/mm 2 ) , but this difference was not statistically significant ( p = 0.935) ( Figure 2 f, right panel).

presented the highly significant and sensitive performance of PSMA as a histopathological marker for disease staging and the discrimination between low- and high-risk, as well as a positive correlation with the Gleason score.

However, we observed a highly significant positive correlation between ELN expression and the expression of EMT markers, including VIM, SNAI1, and TWIST.

Moreover, there was a strong trend for a prediction of death during the first 3 months.

With a mean change difference of 4.5 points between arms (very close to the MCID criterion of ≥5 points), overall satisfaction showed a trend towards a clinically meaningful impact in the intervention arm.

Introduction Breast cancer is the most frequent cancer among women, and its incidence shows an increasing trend, while its mortality is slightly decreasing, although it is still the highest of all cancers in women.

Prevalence of genotypes 16, 18, 59, 66, and 68 increased at three to nine months from baseline both in single and multiple infections, whereas genotypes 31, 33, 35, and 45 showed a decreasing trend.

Final data from this phase II clinical trial reported a positive trend in mean overall survival (mOS) for patients treated with neoadjuvant GVAX alone (35.0 months compared to 24.8 months in historical controls) in comparison with patients who were additionally treated with cyclophosphamide (mOS 15.4 and 16.5 months) [ 29 ].

The incidence of D-NETs has shown an increasing trend from 0.027/100,000 in 1983 to 1.1/100,000 in 2010 [ 3 ] paralleling the increasing volume of upper GI endoscopies [ 4 ].

Interestingly, a decreasing trend of the performance against the number of samples (lesions) used for testing the AI model was noticed as shown in Figure 1 .

This study showed a strong trend towards higher GLS protein expression in the high proliferative ER+ tumours in invasive breast cancer and in DCIS.

A borderline significance was observed for age: young patients (<55 years) were more favorable to be in P4 (24.2%) compared with the elderly (≥75 years) who were allocated in P1 (25.9%) ( p = 0.055).

By fitting the M1-M7 signatures to the BABE data, the discriminatory performance of 5 signatures was confirmed (in terms of AUC value) but borderline significant for the remaining 2 ( Figure 3 ).

Especially striking is the highly significant increased proportion of patients with respiratory failure who require stronger oxygen support in the G-CSF group.

In terms of TFR, ELTS score had a weak trend in predicting successful TFR [ 89 ]. 5.7.