Similar to the trend we observed in tumor-derived SUV max , SUV max in post-surgical scarring also showed a trend towards a positive correlation with myocardial tracer uptake (Pearson’s r = 0.49, p = 0.06) Otherwise, there were no significant correlations between radiotracer uptake in normal organs and post-surgical scarring ( Table S2 ). 3.5.
High baseline seric levels of VEGF in BC patients have been found to correlate significantly with increased OS, and were of borderline significance ( p = 0.06) with improved PFS following bevacizumab treatment [ 141 ].
However, by separating the glands into two parts with the top composed of pit and isthmus and the bottom composed of neck and base, we observed an almost significant ( p = 0.06) decrease in nuclear positive cells in the neck and base of H. pylori positive tissue compared to non-infected tissue ( Figure 6 B).
A trend toward significance was observed for four-year PFS (71%, 58%, and 42% for AA, AG, and GG genotypes, respectively; p = 0.06), while four-year OS differed significantly across the three subgroups (78%, 61%, and 45%, respectively; p = 0.04).
Detection of FRE colonization on pre-transplant testing predicted for subsequent re-hospitalization ( p = 0.002); the detection of FRE colonization, including the post-transplant samples, was of borderline significance ( p = 0.06).
A nearly significant lower presence of ctDNA DDR gene mutations was found in non-smokers compared with ever-smokers ( p = 0.06) in the 3-gene subset analysis.
The presence of high endothelial venules, assessed by the MECA-79 antibody, was not associated with any of the factors studied; however, it showed a trend ( p = 0.06, χ 2 = 3.4) for a negative association with p62 nuclear expression.
Patients with delayed surgery (C3) showed a non-significant trend toward increased risk (HR 5.05; 95% CI 0.53–48.6; p = 0.161), and those who did not undergo indicated surgery (C4) demonstrated borderline significance (HR 7.27; 95% CI 0.92–57.5; p = 0.060).
When compared to the nIBC cohort, this decrease was significantly higher in TN IBC ( p = 0.007), borderline significant ( p = 0.06) in the HR+ IBC and not significant in HER2+ IBC ( p = 0.37).
After 4 weeks, X-rays and μCT analyses showed a trend of reduction in osteolytic lesion incidence (chi-square test; p = 0.06) ( Figure 2 b and Supplementary Figure S2a ) along with a reduced osteolytic area ( Figure 2 c,d) in the tibias of N-Cadherin High compared to N-Cadherin Low cell-injected mice.
CRT significantly reduced local progression rates (32% versus 46%, p = 0.030) and showed a trend towards better median PFS (9.9 versus 8.4 months, p = 0.060) and longer median time without retreatment (6.1 versus 3.7 months, p = 0.020).
Intriguingly, Binet stage C patients tended to have a higher level of RelB activity compared to stage A patients ( Figure 6 F), but this did not quite reach significance ( p = 0.06), likely due to three Binet stage A cases that had high RelB activity (including one with ATM loss).
PSI was significantly correlated with CBCL total score (r = −0.37, p = 0.001), the CBCL internalizing score (r = −0.34, p = 0.002) and the SDQ total score (r = −0.44, p = 0.0001), whereas the relation with the CBCL externalizing score was nearly significant (r = −0.21, p = 0.06).
We observed a statistically significant genotype-by-sex interaction for MDM4 rs4245739 ( p = 0.01) and a borderline significant interaction for rs1563828 ( p = 0.06).
Stage IV disease demonstrated a borderline significant association with worse disease-free survival, with a HR of 2.81 (95% CI 0.96–8.27, p = 0.06) compared to stages I-III.
Although only approaching significance, DGE and PPH presented a higher frequency in the PPAP population than in the no-PPAP group ( p = 0.06 and 0.08, respectively).
There was an observed trend towards longer operative time for the MIS-ILND approach (mean difference 28 min; 95% CI −2 to 58 min, p = 0.06), particularly with the robotic-assisted technique.