Myh1 showed a significant change while Myh4 , and Myh8 genes showed a trend that did not yh1, Myh4 , and Myh8 genes.
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Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions.
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The sentences
Redirected splicing resulted in a significant prolongation of twitch half relaxation time and a strong trend toward increased peak twitch force and peak calcium, although these changes did not reach statistical significance ( Figure 9C ).