Comparing Perioperative Outcomes of Choledochoduodenostomy and Roux-en-Y Hepaticojejunostomy in Difficult Choledocholithiasis: The Experience of a Brazilian Tertiary-Level University Hospital.

n=11; 64.7%), with a trend toward significance (p=0.063), whereas previous pancreatitis was comparably less common in both groups (n=3; 10.3% vs. n=3; 17.6%; p=0.48).

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Although these associations did not reach statistical significance, they align with prior findings that emphasize the technical advantages and lower anastomotic tension achieved in cases with more dilated ducts [ 2 , 12 , 16 , 17 ].

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In multivariable analysis, no variable independently predicted 30-day morbidity or mortality, though cholangitis showed a trend toward higher risk and bile duct diameter toward protection.

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The presence of cholangitis demonstrated the highest odds ratio (OR = 6.09; 95%CI 0.40-93.51; p = 0.189), suggesting a possible trend toward increased risk, though this did not reach significance.

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