Dynamic Integrative Immune Profiling Reveals Early Biomarkers of Response and Prognosis in Advanced Gastric Cancer Treated with Nivolumab Plus Chemotherapy.

Cancers (Basel) · 2025 · PMC12523374 · PMID 41097658

Europe PMC DOI

hedged sentences

0.0760

closest p · 1.5× alpha

0.0760

boldest claim

The sentences

did not reach statistical significancep = 0.076so close (0.05 < p ≤ 0.1)

showed a trendp = 0.076so close (0.05 < p ≤ 0.1)

Although NLR did not reach statistical significance in this cohort, week 1 NLR showed a trend toward prognostic relevance (HR = 2.034, p = 0.076) ( Figure 4 ).

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a favorable trendno p-value reported

Baseline PD1 + CD8 + T-cell levels also showed a favorable trend for PFS.

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