Smart Formulation: AI-Driven Web Platform for Optimization and Stability Prediction of Compounded Pharmaceuticals Using KNIME.

Pharmaceuticals (Basel) · 2025 · PMC12389346 · PMID 40872628

Europe PMC DOI

hedged sentence

0.1090

closest p · 2.2× alpha

0.1090

boldest claim

The sentences

a negative trendp = 0.109not close (p > 0.1)

did not reach statistical significanceno p-value reported

While temperature demonstrated a negative trend (R = −0.336, p = 0.109), it did not reach statistical significance, suggesting that its effect might be better captured through interaction terms or non-linear modeling approaches.

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