Direct Oral Anticoagulants Versus Vitamin K Antagonists in Chronic Kidney Disease Patients Undergoing Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.

Cureus · 2025 · PMC11829700 · PMID 39958405

Europe PMC DOI

hedged sentence

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closest p · 0.8× alpha

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boldest claim

The sentences

showed a trendp=0.04actually significant

marginal significanceno p-value reported

While DOACs showed a trend toward reduced mortality (RR: 0.90, 95%CI: 0.81-0.99, p=0.04), the marginal significance and confidence intervals approaching the null value suggest a modest effect.

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