Nonspecific increase of αβTCR⁺ double-negative T cells in pediatric rheumatic diseases.

B cells were also slightly reduced in rheumatic children, which was mildly significant only when expressed as a relative (percentage) count.

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Conversely, when αβ + DNT cells were expressed as an absolute cell count, they showed a trend of a negative correlation with pediatric SLE Disease Activity Index (pSLEDAI), though this did not reach statistical significance either ( r = − 0.523, P = 0.479), likely due to the small sample size.

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