“trending toward significance”

In the combination, SBI-457 attenuated sorafenib-induced β-catenin upregulation, trending toward significance ( p = 0.054; Figure 2 C).

Logistic regression showed comorbidity of asthma trending toward significance ( p = 0.054) in association with bony dehiscence. 5.

Results BRIEF-A ratings While adults with ASD were rated by both themselves and their informants overall on the BRIEF-A as having more difficulties with inhibition compared to controls, this main effect of group across both self and informant ratings was only trending toward significance ( F (1,39) = 3.95, p = 0.054, d = 0.25).

Sitting time (h/week) was positively associated of depression symptom severity and vigorous intensity exercise had a negative association that was trending toward significance ( p = 0.054).

Significant correlations were noted at six months between levels of alkaline phosphatase and both ALT (p = 0.0101) and AST (p = 0.0009), as well as an additional correlation trending toward significance between ALT and alkaline phosphatase at one year (p = 0.0547).

Further comparisons showed that the significant theta activity was present in the collaborative task condition when compared to the single active task ( p = .013) and trending toward significance, compared with the single passive task ( p = .055).

3.2.3 PAS ‐positive goblet‐cell hyperplasia HDM also induced significant goblet‐cell metaplasia (exposure p < 0.001; sex p = 0.033), with genotype trending toward significance ( p = 0.055).

In addition, although no significant differences in subscale or composite scores were noted for the Mullen Scales of Early Learning or the Vineland Adaptive Behavioral Scales, increased impairments in the stereotypical behavior subscale of the ABC were observed for children of mothers possessing antibodies reactive to LDH in any context ( P =0.024), CRMP1 (trending toward significance; P =0.055), as well as combined reactivity to LDH and STIP1 ( P =0.015), or LDH/STIP1/CRMP1 ( P =0.007) in comparison to children with an ASD whose mothers lack IgG reactivity to these antigens.

Posterior densitometry decreased from 18.33 ± 5.82 GSU to 16.32 ± 4.62 GSU, trending toward significance ( p = 0.055), but post-hoc analysis confirmed a significant reduction ( p = 0.0414).

Univariate measures for anti-inflammatory markers reported significant main time effects for IL-4 (p = 0.001) and IL-7 (p = 0.033) with IL-13 trending toward significance (p = 0.055).

A significant difference was found on low registration ( F (2,17) = 4.30, p = 0.031, ES = 0.34) and sensation sensitivity scores ( F (2,17) = 5.06, p = 0.019, ES = 0.37) with differences on touch processing trending toward significance ( F (2,17) = 3.43, p = 0.056, ES = 0.29).

Age emerged as a significant covariate for multiple groups including CVD/AD (β = 0.260, p < 0.001), LBD (β = 0.263, p < 0.001), ADD (β = 0.205, p < 0.001), PDD (β = 0.134, p < 0.001), and BV (β = 0.059, p = 0.002), while showing protective effects for CBD (β = −0.049, p = 0.056, trending toward significance).

In the open-field test, evaluation of the total distance travelled over 30 min in the novel environment showed significantly increased locomotor activity in 15-week-old CYP2C19Tg-Hem mice compared with Wt mice ( P =0.027), which was already trending toward significance at 7 weeks of age ( P =0.056; Figures 5a and b ).

Of note, abdominal pain was trending toward significance ( p = 0.056).

One QUS texture parameter, ΔASD-COR, was trending toward significance (p = 0.056).

The age-adjusted difference in EAT volume between males and females was trending toward significance (8.0 ± 3.74 cm 3 vs. 7.92 ± 3.84 cm 3 , p = 0.0561).

GSEA of MicroRNAs (miRNAs) revealed that the differentially expressed gene sets from both DDR1i and RUNXi treatment groups overlapped with genes regulated by miR-93, significantly with miR-93-5p ( p = 9.27e−3 for DDR1i; p = 9.86e−6 for RUNXi), and trending toward significance for miR-93-3p ( p = 0.0566 for DDR1i; p = 0.086 for RUNXi) ( Figures S5 B and S5C). miR-93 expression is known to be repressed by RUNX1 and other members of the RUNX TF family and has been implicated in migration and proliferation of normal and cancerous cells ( Bao et al., 2020 ).

Specifically, shoulders with less than 6° of native retroversion had nearly twice the force following capsulolabral repair compared with shoulders with greater than 6° of retroversion (47.3 ± 37.7 N vs 23.6 ± 21.7 N), although this finding was only trending toward significance ( P = .057).

Bootstrap resampling (1000 iterations) confirmed LargeDependenceEmphasis as the most stable discriminator (selection frequency 92.4%), maintaining consistent predictive value (coefficient: −0.404; standardized odds ratio: 0.667; 95% CI: 0.44, 0.89; trending toward significance with p = 0.057) across validation folds (Table 6 ).

Males treated chronically with a low dose (10 mg/kg) of LEV yielded a more normally distributed set of edgewise covariance trending toward significance compared to the vehicle (saline) treatment group of the same sex (KS = 0.01, p = 0.057).

A multivariate Cox regression model, including key clinical covariates, showed that the top performing CD8+ T cell functionality signature, cytolytic, was an independent prognostic biomarker for OS (HR: 5.0, 95% CI: 1.1 to 1.23; p=0.041) and trending toward significance for DSS (HR: 4.6, 95% CI: 0.96 to 23; p=0.057) ( table 1 ).

The main effect of treatment was trending toward significance ( P = 0.057) for Pielou's Evenness, and there was no effect of treatment on Faith's Phylogenetic Diversity Index ( Supplemental Table 2 ; P > 0.05).

A similar relationship was trending toward significance ( p = 0.0571) in SA1.

Last, in Model 4, participants who identify as heterosexual experienced a 5.04-point increase in the odds (95% CI = 0.95, 26.88), trending toward significance, of reporting sex with multiple partners during the measurement period than participants identifying as other sexual identities ( p = 0.058).

Household ownership of a radio was significantly associated with health-care utilization, and was trending toward significance with diarrhea ( P = 0.058) and fever ( P = 0.06).