One of the most significant limitations is the relatively small number of patients recruited, which likely contributed to some results trending toward significance but not reaching it.
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“trending toward significance”
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There was no statistical difference in the probability of being diagnosed with DVT among moderate and severe COVID-19 cases ( P = .197); however, the time to event analysis by severity of COVID-19 symptoms using Kaplan-Meier plot shows ( Fig 1 ) that the likelihood of diagnosis of DVT for severe category of patients with COVID-19 was higher and trending toward significance as was seen in the univariate Cox regression (hazard ratio, 2.13; 95% CI, 0.64-7.08) than that for patients with mild to moderate disease.
Type of insurance payer, while trending toward significance with higher rates for women with private insurance, did not achieve statistical significance.
We do see that the association of AA with Hispanic patients is trending toward significance.
In contrast to WT cells, both initial and final TEER decreased in CF cells treated with ETI under both normal and high glucose (trending toward significance in high glucose), and this was not impacted by insulin (Fig. 3 e, f).
Similarly to lipogenic gene induction, both GW3965 and 4β-HC had a modest but statistically significant 1.5-fold increase in C13-labeled C16:C16:C16 TAG, or trending toward significance for C16:C18:C16 TAG, whereas 24-HC caused no significant change ( Fig. 3 E).
Whereas the improvement in the models was either statistically significant (comparing health center and nonspatial models) or trending toward significance (comparing spatial and nonspatial models), the absolute differences in the AUCs from spatial and nonspatial models were modest.
This model included multiple covariates identified as or trending toward significance during the univariate analysis (age, IFN-γ, and response to treatment [COA]).
We also examined genes that were trending toward significance, as these might provide insights into additional genes driving pathogenesis of canine pemphigus, but were under-powered in our study of four cases ( Figure 1C ).
The interaction between probability of profile membership and child sex was trending toward significance.
This ratio being quite low, and the p < 0.084 of the three-way interaction trending toward significance, we infer that the performance of participants is different in the two experiments.
This pattern was also observed in two ‘task-positive’ systems of the early visual and sensorimotor with differences trending toward significance when combined.
Quantitatively, reductions in caregiver burden and improvements in resident’ quality of life and loneliness were statistically significant or trending toward significance, particularly within the first month of intervention.
Protective effects trending toward significance were detected at two loci identified in single-variant analyses: an intronic variant in FBLN7 (the gene encoding fibulin 7) and at three variants near pyridoxal (pyridoxine, vitamin B 6 ) kinase ( PDXK ).
With 21% O 2 , CBS KD resulted in marked increase in [Ca 2+ ] c response trending toward significance compared with Scr fASM.
With DAPT treatment, we observed a significant increase in the % NEUROD1 + cell population of the MEL1-INS GFP/w cells and an increase trending toward significance in the % NEUROD1 + population of the H1 cells (Figs. 4 A,B,D,E, and S7 D).
Only the mid (THC) exhibited statistical significance between the vehicle ( p = 0.0408), with the high (THC) group trending toward significance at a p -value of 0.1604.
Yet, when we pool across object weights as well as the subject type (amputee or non-amputee), the object was 1.5 times less likely to slip with joint torque feedback than with no feedback, a result trending toward significance (see Fig. 11 ).
Threat effects 15 Only the interaction effect on the second standardized test, the verbal GRE, was trending toward significance at the 0.11 level (see Table 4 ).
Instead, the transcripts of AR v567es and AR-V7 (trending toward significance) were upregulated in enzalutamide-resistant tumors, while the levels of AR-V4 or AR-FL transcript did not differ (Figure 6A - D ).
In addition, areas AM and RL were trending toward significance, but areas AL, LI, and S1 did not show significant retinotopic anisotropy in coherent motion correlation (Fig. 5j ; V1: −0.81 ± 0.05, t 9 = 5.3, −10.3, p = 1.4 × 10 −6 ; LM: −0.44 ± 0.08, t 9 = −3.3, p = 4.3 × 10 −3 ; AL: 0.03 ± 0.14 , t 9 = −1.1, p = 0.85; PM: −0.78 ± 0.06, t 9 = −8.9, p = 4.5 × 10 −6 ; LI: −0.04 ± 0.11, t 9 = −0.6, p = 0.73; RL: −0.27 ± 0.10, t 9 = −2.1, p = 0.035; AM: −0.36 ± 0.14, t 9 = −2.0, p = 0.036; S1: −0.14 ± 0.09, t 9 = −1.3, p = 0.11; Bonferroni-corrected threshold p < 0.006, mean ± s.e.m., single-sample t test).
MEV The video condition was not significantly associated with the oxytocin response; however, findings were trending toward significance ( Table 1 ).
IFNG was significantly upregulated in DLE ( p = 0.0237) and trending toward significance in other CID conditions ( Figure 3D ).
When further investigation into serologic markers of autoimmune disease was performed, it was determined that patients with CSU as compared to control subjects had significantly higher levels of anti-thyroid peroxidase (anti-TPO) antibodies, antinuclear antibodies (ANA), antithyroglobulin (i.e., antimicrosomal) antibodies, rheumatoid factor, anti-transglutaminase IgA antibodies, and anti-parietal cell antibodies with anti-dsDNA, and anti-cardiolipin antibodies trending toward significance.
It is interesting to note that although improvement in prophylaxis dosing frequency from thrice-weekly to twice-weekly was not statistically significant ( Table 3 ), it was still trending toward significance in our survey.