Barely Significant
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“trend toward significance”

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In the literature

trend toward significanceP =.071.4× alpha
At 3 months, e-visit participants were 3.1 times more likely to have reduced their cigarettes per day by at least 50% (95% CI 1.2-8.2; P =.02), with a similar trend toward significance at 1 month (OR 4.1, 95% CI 0.9-18.8; P =.07).
trend toward significancep = 0.0721.4× alpha
Physical therapy remained a strong protective factor (OR = 0.025, 95% CI: 0.002–0.314, p = 0.004), while higher CGI scores (OR = 2.733, 95% CI: 1.127–6.626, p = 0.026) and trauma history (OR = 8.326, 95% CI: 0.829–83.664, p = 0.072, trend toward significance) were associated with worse outcomes (Table S5 ; Figure 2c,d ; Table S6 ). 4 Discussion As the first systematic investigation of FMDs in China's Han population, this study provides comprehensive insights into demographic characteristics, phenotypic presentations, psychiatric scales, and prognostic outcomes.
trend toward significanceP = 0.0751.5× alpha
A significant time ∗ group interaction was found in VO 2 max in absolute and relative values, and total test duration ( P = 0.007, P = 0.006, and P = 0.003, respectively), whereas a near-significant trend toward significance was observed in the time ∗ group interaction in maximal heart rate ( P = 0.075).
trend toward significancep = 0.0791.6× alpha
Additionally, the number of App Modules Completed showed a stronger trend toward significance (OR 1.67, p = 0.079) than in the whole cohort, suggesting that behavioral engagement and sleep hygiene may be particularly effective drivers of pain relief when systemic inflammation is controlled.
trend toward significanceP =0.081.6× alpha
The use of amiodarone did trend toward significance in our study ( P =0.08) and has been previously associated with vasoplegia in the heart transplantation population. 12 In addition, the use of vasopressors before LVAD implantation has been associated with poor outcomes and RHF; we found that those with vasopressor dependence before surgery had >3 times the risk of developing vasoplegia. 13 Our study revealed preoperative kidney dysfunction as being associated with vasoplegia, with those with moderate to severe vasoplegia having a median serum creatinine of 1.6 mg/dL compared with 1.3 mg/dL among those without vasoplegia.