“showed a trend”

Finally, in a 6-week study in duloxetine treated (a serotonin norepinephrine reuptake inhibitor) of 241 MDE patients, only rs4792888 of CRHR1 showed a trend of pharmacogenetics association ( p = 0.054) 32 .

Progression-free survival In the general series, the Kaplan-Meier test showed a trend to significant association between the absence of PTEN mRNA in exosomes and patients with a short PFS ( p =0.054; Figure 1A ).

Administering multiple lower doses (30 mg/kg) also showed a trend toward TTV load increase in healthy volunteers (1.8 log 10 c/mL, 0–2.3 vs. 1.9, 1.3–2.8; p = 0.054) and a significant increase in transplant recipients (3.5 log 10 c/mL, 3.0–6.1 vs. 4.1, 3.5–6.4; p = 0.004).

The study of a connection of the blood serum VDR concentration with age of patients with SLE ( table 4 ) showed a trend for lower VDR levels in ageing patients, although the difference in the mean values shown by different age groups was not statistically significant (p=0.054).

Subgroup analysis of patients with pre-operative malalignment showed a trend towards greater improvement in the NDI at 12 months with a C2 UIV ( P = .054).

Decline in eGFR creat was significantly greater in subjects above the 300 mg/g threshold (p < 0.01), while the 30 mg/g threshold showed a trend toward larger decline (p = 0.054).

The ECAR showed a trend towards increased responses in OP-MG (1.8-fold) compared to controls (1.4-fold, p = 0.054) ( Fig. 1 D).

The ANOVA on change in FAR from T2 to T3 showed a trend for a Group effect ( F 1,38 = 3.94, p = 0.054, η 2 p = 0.09; BF 10 = 1.451; Figure 5d ), with greater change for the SF, but no significant Type effect ( F 1,38 = 0.281, p = 0.599, η 2 p = 0.01; BF 10 = 0.237) and Type × Group effect ( F 1,38 = 0.311, p = 0.580, η 2 p = 0.01; BF 10 = 0.306). 3.6.

Among the clinical factors, BMI was not significantly associated with worse PSQI scores, although it showed a trend ( p = .054).

Nontreosulfan-based MAC showed a trend toward increased mortality compared with RIC (HR, 4.0; 95% CI, 1.0-16.2; P = .054).

However, patients with a higher viral load at hospital admission showed a trend toward viral load reduction ( p = 0.054) in the nitazoxanide group vs. the placebo group.

Functional independence An improvement in FIM total score from baseline to month 6 occurred in the ITB arm (+2.68 (10.31)), while a worsening occurred in the CMM arm (−2.58 (11.00)) ( table 3 and figure 3 ); the analysis showed a trend towards a treatment effect in favour of ITB over CMM (P=0.0540).

High frequency power during NREM sleep showed a trend toward being associated with lower overall DASS-measured psychopathology ( r = −0.20, p = 0.054) along with significantly better emotion regulation ( r = 0.23, p = 0.027) and significantly fewer nightmares ( r = −0.26, p = 0.011; Figure 4 ).

Entering hippocampal MTR and hippocampal DIR lesions as predictors revealed that only hippocampal [Glu] showed a trend for predicting PAL trials at first attempt (coeff.=0.60, 95% CI −0.01 to 1.13, p=0.054, PCC=0.59).

Older age and fewer than three metastatic sites were significantly associated with improved PFS ( p = 0.041 and p = 0.009, respectively), whereas the presence of liver metastases showed a trend toward poorer PFS ( p = 0.054) [ 25 ].

Furthermore, the entire number of medical disorders associated with FXAND, including anxiety, depression, ADHD, and ASD, was significantly lower for greater AR-Sb ( p = 0.02) and showed a trend for higher AR-mPCR ( p = 0.054) ( Figure S1 ).

Only patients aged ≥ 75 years showed a trend toward a significant association with mortality in the chi-square analysis across the three age groups, with a P value at the margin of statistical significance ( P = 0.054).

The comparison of mean values only showed a trend with regard to possible group differences ( p = 0.054).

While a C+T PRS with a single p ‐value of 1 only showed a trend ( p = 0.054) in predicting AD diagnosis combined with baseline NfL, we found a highly significant predictive effect for AD diagnosis for PRS‐CS combined with baseline NfL.

Carotid lesion sizes showed a trend toward a significant inverse correlation with HDL levels ( r =-0.125; P = 0.054).

S1 F ); however, phosphorylation of CREB Ser133 , which is induced by the adrenergic-PKA signaling axis, showed a trend for increased phosphorylation ( P = 0.054) in the early active phase (versus early rest), which was absent in fasted early rest phase mice ( Fig. 4 L ).

Picrosirius Red (PSR) staining of histological cross-sections showed a trend towards interstitial fibrosis ( p = 0.054) ( Supplementary Figure S2J ), which was paralleled by an increased expression of the extracellular matrix proteins Collagen alpha-1(I) chain ( Col1a1 ) and Fibronectin ( Fn ) whereas Collagen alpha-1(III) chain ( Col3a1 ) and connective tissue growth factor ( Ctgf ) remained unchanged in cKO compared to WT mice ( Supplementary Figure S2K ).

The non‐dominant‐hand PPT score increased significantly in sham participants (from 15·2(2·1) at baseline to 16·3(2·1) post‐training; P = 0·002), and the dominant‐hand PPT score showed a trend towards an increase (from 17·0(1·8) to 17·5(1·8); P = 0·054).

Of note, increased EBRT treatment length also showed a trend toward statistical significance (OR 0.965, 95% CI 0.931–1.001, p = 0.054). 3.3.

Cluster one showed a significantly higher contribution in HPV-negative tumors compared to HPV-positive tumors (p = 0.033), while cluster three showed a trend towards lower contribution in HPV-negative tumors compared to HPV-positive tumors (p = 0.054) ( Fig. 3 c). 3.4 Tumor response, HPV status, and conventional DWI and NG-IVIM DWI parameters Due to the rare occurrence of PD in HPV-positive patients within one year (2 out of 18 patients), subgroup analysis was only performed for the HPV-negative patient group, in which 6 out 18 had PD within one year after treatment.