TRPV1 expression was not significantly altered in CM-treated group compared to vehicles-only control group but the CM-treated group showed a trend towards reduction in TRPV1 protein expression when compared to paclitaxel ( p > 0.05). 3.7 Effect of CM extract administration on microglia activation markers Administration of paclitaxel alone or paclitaxel +250 mg/kg CM extract did not change the microglia status in the spinal cord of mice as dem
Patients with a primary site in the small intestine showed a trend toward T3–T4 (42.2%), whereas primary sites in the colorectum had a higher proportion of T1–T2 (40.0%, p = 0.050).
WT + Trp and HET + Trp mice showed a trend toward a decrease in the relative content of adipose tissue (22.4% and 5.9%, p > 0.05) and an increase in muscle tissue throughout the study (5.9% and 2.9%, p > 0.05).
When comparing the different clinical groups of the PH patients, only LVEF showed a trend of difference, mainly driven by the decreased values in the PH group 2 and group 2/3 ( p = 0.050). 3.2.
IVD height decreased with age, showed a trend toward significantly decreasing with spinal level ( p = 0.05), and showed no significant interaction between age and level (Figure S6C ).
Tested in the same tissue samples, 3-HK production from both precursors showed a trend to increase as a result of the NAC treatment, but the differences from saline-treated controls did not attain statistical significance (* p > 0.05; Mann–Whitney test) ( Figure 3 B). 3.4.
In term of OS, EP showed a trend significant advantage over PC (HR = 0.83, 95% CI: 0.65–1.0; P = 0.05).
Notably, immediate post-procedural angiography showed a trend toward superior results in the drug coated balloon group in terms of MLD, DS%, and acute lumen gain ( p < 0.05) (Table S3 and Table 4 ).
We observed that FS application showed a trend towards reducing the ankylosis compared to the control group without reaching statistically different levels (p > 0.05) (Table 1 ; Fig. 2 ).
Furthermore, ITGB4 high patients showed a trend toward poorer survival (log-rank p < 0.05, Figure 4C ).
Similarly, MHC class-I HLA gene, HLA-F showed a trend akin to HLA-DQA1 (Fig. 5C and p < 0.05).
The pooled analysis revealed that PD-L1-positive patients showed a trend toward a better response to therapy (OR =2.61; 95% CI: 1.01–6.70, P=0.05) ( Figure 4C ).
The proprioceptive acuity showed a trend of decline to 3.08 ± 2.07° in dorsiflexion and to −2.59 ± 1.94° in plantar flexion ( p > 0.05).
Physical examination of patients revealed crackles in 8.2% (n = 82) and showed a trend of its presence in patients with persistent post-COVID-19 symptoms (9.9% vs. 5.8%, p = 0.05).
The C3 −/− mice showed a trend towards higher numbers of phospho-histone H3-positive (PHH3 + ) cells, i.e. cells proliferating at the time of sacrifice, in the GCL after IR (Figure 3C-3D , P = 0.0500).
Among these behaviors, urination showed a trend more similar to the jumping ( Fig. 2 , Qui-square test for trend, P<0.05).
Furthermore, single visceral organ and/or soft tissue involvement significantly decreased progression risk (p = 0.01), whereas increased S100B level showed a trend towards PFS shortening (p = 0.05).
Comparing OS of all patients based on TP53 mutation status showed that no TP53 mutation (median, 33.9 months) vs TP53 monoallelic (median, 12.5 months) vs TP53 multihit (median, 9.4 months) was significant ( P < .0001) ( Figure 2D ), whereas comparison of TP53 monoallelic vs multihit showed a trend toward worse outcome ( P = .05).
Additionally, it showed a trend-level positive correlation with defecation difficulty (r = 0.19, p = 0.05), and a trend toward a negative correlation with solid stool leakage (r = −0.19, p = 0.05).
Anxiety scores (HADS-Anxiety) showed a trend toward improvement in the intervention group, reaching borderline significance at T48 ( p = 0.05).
The transverse temporal gyrus, the location of primary auditory (A1) cortex showed a trend sex-by-TES-thickness interactions predicting gray matter thickness (α = p<0.05, uncorrected) ( Fig. 1 ).
ruthenicum roughage addition to the diet ( Figure 3B ); the relative abundance of the NK4A214_group showed a trend of increasing and then decreasing ( p < 0.05) with increasing levels of L. ruthenicum branches additions in the diet ( Figure 3C ); and the relative abundance of sheep ruminal microbiota phylum level species among groups had no significant effect ( p > 0.05) ( Figure 3A ).
Overall, overweight BMI showed a trend towards better PFS than normal BMI, even after adjusting for other risk factors (aHR 0.66, 95% CI 0.44–1.00; p = 0.050).
The CFQ-R questionnaire showed a trend towards an improvement of the physical domain score as the majority of the patients scored higher after treatment (88% (17; 100) to 88% (58; 100), p = 0.05).
genes that were ranked by correlation coefficient for the delta change in glycemia at 2h and change in gene expression at the same time showed a trend towards enrichment of the Hallmark geneset for glycolysis ( p = 0.05).