“showed a trend”

22 Trials of atacicept, which blocks the activity of two B-cell survival factors, BAFF and APRIL were terminated prematurely in phase II/III due to safety concerns; however, the data showed a trend to benefit for the higher dose tested. 23 Studies of B cell-directed agents continue, with modifications to improve efficacy, such as obinutuzumab, an anti-CD20 mAb engineered for enhanced cytotoxicity ( NCT02550652 ).

Reports by Central Asian countries showed a trend similar to last season, only reporting low‐intensity influenza activity.

Male patients showed a trend towards improved survival when compared to female patients (median OS 24.5 vs. 17.6 months, n.s.) Patients with a sarcomatoid component showed poorer outcome than patients without (median OS 11.1 vs. 24.5 months, n.s.).

A greater than 3-month delay between cystectomy and last TUR showed a trend toward upstaging, which means that delaying cystectomy for BCG therapy may worsen prognosis.

Patients in adenoma group showed a trend toward male gender and younger age as compared to those without adenoma.

There was no statistical difference between basal PTH level and preincision level but showed a trend toward higher values at the latter occasion.

tujafilina population analyzed in the present study, a statistical analysis of the absolute copy numbers of gro EL and atp D revealed that although both endosymbiotic bacteria showed a trend line with a positive slope (0.0540 for B. aphidicola BCt; 0.0296 for S. symbiotica SCt; Fig. 4B ), a significant positive correlation was only observed between the average temperature recorded and the amount of B. aphidicola BCt ( p =0.002).

Quantile-quantile (QQ) plots for various classes of variants showed a trend towards association enrichment for conserved nonsynonymous variants and deleterious variants mapping to the A band ( Figs 2 and 3 ).

The maximum complication scores were not significantly different between groups ( U = 129.5, P = 0.06), though patients receiving corticosteroids showed a trend towards higher maximum complications scores than those in the control group.

While the data ellipses of the patient diary sleep NRS ( Figure 2C ) showed a trend similar to the MOS-SS, the loess curves of placebo and pregabalin almost overlap, with both demonstrating an almost linear relationship between pain relief and improved sleep ( Figure 2D ).

44,45 Overexpression of WAVE1-A and WAVE1-B (but not WAVE1-C) showed a trend toward increasing the expression of embryonic genes, while knockdown of WAVE1 in embryos through MO-injections caused a downregulation of many genes, including hox genes, indicating that nuclear WAVE1 plays a role in embryonic development ( Fig. 2G ). 45 Co-immunoprecipitation experiments with nuclear extracts of an NLS-WAVE1–A or –B fusion protein were conducted to identify nuclear WAVE1 interactors.

3 Consistent with the theory that aging is an etiologic factor of BPH, our results showed a trend of increasing median PV with advancing age, with the highest PV recorded in the ≥ 70 years group and the lowest PV in the ≤ 60 years group.

The rainfall pattern from 1980 to 2010 showed a trend of decrease in total rainfall received.

The expression of AQP1 in glomeruli of DM eMnSOD-Tg mice showed a trend towards being higher than that of non-DM eMnSOD-Tg mice, but it was not statistically significant ( Fig 3C and 3D ).

Duration of IM IFNB therapy also showed a trend to increase the odds of having a relapse while on therapy with a borderline p value of 0.05.

Moreover, unlike the previous study that showed a trend in favor of doublet agents with respect to OS, but the difference was not statistically significant partly due to the limited RCTs included, we demonstrated for the first time that doublet agents were more efficacious in terms of OS (HR 0.90, 95% CI 0.84–0.96, P =0.002), PFS (HR 0.81, 95% CI 0.76–0.88, P <0.001), and ORR (RR 1.72, 95% CI 1.34–2.21, P <0.001) when compared with single-agent therapy ( Figure 2A and B ) in the anthracyline- and taxane-pretreated breast cancer patients.

Results Decellularization Safranin-O and Fast Green staining of decellularized cartilage showed a trend of decreasing proteoglycan content with the addition of chABC ( Fig 3 ).

A six-week dietary intervention study in junior athletes who were administered an acai berry-based juice blend showed a trend towards increased catalase and glutathione reductase activities, but no effects on glutathione peroxidase at one-hour after exercise phase.

Figure 1 showed a trend: lower testosterone level and lower support from colleagues was predictive for higher depression and anxiety, whereas higher support from colleagues was predictive for lower depression and anxiety.

In contrast, De Jong et al found that uterine carcinosarcomas with non‐endometrioid carcinoma components showed a trend for worse disease‐specific survival compared to carcinosarcomas with endometrioid carcinoma components in 40 tumours, although the difference was not significant 5 .

Advanced age showed a trend of increased fracture risk.

13 Multivariate analysis adjusted for sex, stage, type of surgery, and adjuvant chemotherapy showed a trend toward a higher 2-year survival rate in the 56 patients (33%) who received a TKI perioperatively (96% vs 90%), but no firm conclusion can be drawn in the absence of randomization. 13 An open, randomized, Phase II trial conducted in Asia, after surgery and adjuvant chemotherapy (four cycles of pemetrexed–carboplatin), compared a 6-month course of gefinib with simple monitoring in EGFR-mutated, stage IIIA-N2 NSCLC patients.

Hyperaemic MVR over the whole cycle was low for all stenosis severities, but showed a trend to increase in the most severe strata of stenosis severity ( P trend = 0.01).

Fibrinogen showed a trend towards decreased levels.

Analysis of a subset of native renal biopsies showed a trend of a greater number of biopsies comprising more than three cores in the adequate group as opposed to the suboptimal and inadequate group after each set of interventions, but the trend was not statistically significant.