Insertion of the entire operon into the lacZ gene was facile (as judged by PCR across an insertion junction) and also showed a trend of increased insertion efficiency as a function of incubation time; after 3 days of incubation, 25/25 screened colonies tested positive for the insertion.
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In the literature
17 Of note, a Phase III trial testing topotecan treatment versus PLD treatment showed a trend toward a higher RR in the platinum-resistant OC patient subset treated with PLD, although there was no improvement of PFS or OS. 18 , 19 Gemcitabine Gemcitabine could be considered an alternative to PLD for treatment of platinum-resistant OC.
At 4 weeks, SCC implants showed a trend toward increased PCNA positive cells compared to fresh SCC cells/mm 2 tissue) supporting continued proliferation throughout engraftment.
The count of doxorubicin-specific fluorescence spot among the four groups showed a trend of change similar to the trend seen in doxorubicin penetration distance ( Table 1 ).
In addition, using the highest effective dose (20ng/ml), we found that SCF alone or SCF+G-CSF induced significant enhancement of neurite outgrowth, whereas G-CSF alone only showed a trend toward increased neurite extension but did not reach a significant level ( Figure 2G-K ).
Also, schooling showed a trend for non-statistically significant difference between SMC and MCI.
In the present study, the plasma ACTH level only showed a trend of an increase after combined corticosterone and EFs treatment without statistical significance.
Median PFS showed a trend for improvement in the combination treatment at 5.2 months compared with 3.7 months in the panitumumab-placebo arm [ 100 ].
PET/CT showed a trend towards higher diagnostic accuracy than WB-MRI in detecting residual/recurrent tumours or second primary tumours.
Regardless, forager honey bees infected with IAPV at day 2 post-injection showed a trend of foraging earlier in the morning compared to that of the control group.
We showed a trend of significant difference in the overall survival of patients with a methylated MGMT promoter, compared to those with an unmethylated promoter.
The data from stroke participants also showed a trend similar to neurologically intact participants.
Although insectivores showed a trend toward being disproportionately affected in our study, it was not significant.
4 , lane 4) mutant strain showed a trend towards lower levels of activated Cek1p, although this result was not statistically significant.
Nevertheless, on evaluation of the percentage of fibers involved in a specific network, the cases showed a trend to present a lower ratio of fibers in both networks; being statistically significant in the left hemisphere for both networks ( Figure 5 and 6 ).
While large ICH volume and presence of IVH showed a trend toward association with remaining comatose, in the end only GCS score emerged as an independent predictor of awakening.
Our results showed a trend towards decreased Th17 frequency in ART-naïve subjects compared to all other groups, (ART-naïve: 0.337±0.406% vs.
As for T cells, in all myeloid cell subsets examined, Hap 2 homozygotes showed a trend for reduced splicing of exon 6 compared to the other haplotypes, significantly so in most conditions.
In comparing 0N3R tau to the other five brain tau isoforms, most showed a trend toward less MAPK activation, with only 2N4R tau showing significantly less activation.
The findings showed a trend towards loyalty to a particular pharmacy by older consumers.
The use of the CB 2 agonist JWH015 also showed a trend toward a dose dependent protective effect as well ( Figure 2B ), suggesting the importance of the CB 2 receptor.
116 In ZSF1 rats, an animal model of obesity, hypertension, and metabolic syndrome, chronic caffeine consumption showed a trend toward increasing plasma NE levels. 117 In human subjects, clonidine reduced alertness, impaired cognitive performance, and slowed saccadic eye movements; caffeine antagonized these impairments and opposed the blood pressure lowering effect of clonidine. 118 One interpretation of this study is that caffeine boosts noradrenergic signaling.
Although g s showed a trend towards a decrease, there was no significant difference between the low and high light under the low soil moisture.
19 The analysis of 134 incident cases showed a trend toward an increased hazard ratio of 1.50 (95% CI, 0.76–2.96) in the high BMI (BMI >27.5 kg/m 2 ) group.
Patients with EPHA2-positive tumours showed a trend toward inferior overall survival.