Compared to controls, non-activated and CD3+CD28-activated CD4 + T cells from patients showed a trend toward reduced respiration and glycolysis ( Figure 1 Ci), and the increase in OCR and ECAR levels upon CD3+CD46 activation—which was present in all HDs—was absent in CD46-deficient individuals ( Figure 1 Ci).
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Analysis of this dataset alone showed a trend towards an effect of age on the rise in Aβ levels in the first 6 hours.
However, when computing coherence across all trials and comparing the decision stage with baseline, we found a very similar pattern of results (with P2, P3, and P6 showing a significant enhancement of low-frequency coherence during the decision stage; P4 showed a trend for significance of 0.031).
In accordance with the AXIOM trial, the majority of trials with IM IFNb-1a showed a trend towards better quality of life, particularly in the physical domains, or at least a stable quality of life [ 19 , 20 , 21 ].
Mutations of STAG2 and TP53 showed a trend for co-occurrence with a synergistic negative effect on prognosis when both mutations were present.
Interestingly, Prostratin also showed a trend for enhancing effect of PEP005 on latent HIV reactivation.
The time from HIV diagnosis to ART initiation showed a trend of decrease from a median of 50 days initially versus 16 days post-POC testing.
LPS triggered IL-8 production and pre-incubation of LPS with GI-20 showed a trend toward reducing this response but this was not statistically significant.
In addition, the present study showed that lymphocytes in the non-survival group showed a trend towards lower levels as compared with the survival group, without reaching statistical significance.
There was no significant effect of the presence of the moth on RMS at any angle though in almost all cases RMS showed a trend towards higher values when the moth was present ( Figure 6—figure supplement 2 ).
RME showed a trend for slightly increased PPV and slightly decreased sensitivity.
Measurements of weight, blood pressure, and total cholesterol (Table 2 ) showed a trend toward improvement from baseline through 48 weeks that were greater following period 2 with ACTIVE treatment as compared to CONTROL treatment but these were not significant due to the small numbers of patients in each cohort and the large variability within each cohort.
The current study nevertheless showed a trend for a slightly raised vulnerability among women, which a population study in a neighboring country (Sweden) also indicated [ 23 ].
showed a trend towards slightly higher serum TSH levels in women with thyroid autoimmunity in the first trimester of pregnancy compared to women without thyroid autoimmunity and that women with asymptomatic autoimmune thyroid disease who were euthyroid in early pregnancy carried a significant risk of developing hypothyroidism progressively during gestation, despite a marked reduction in antibody titers [ 11 ].
Neither egg nor fecal pellet production showed a trend of increase or decrease depending on how long collembolans were fed on Bt-maize before the experiments.
Patients with Cord swelling showed a trend toward complete injury at presentation.
Moreover, modified Stoke Ankylosing Spondylitis Spine Score and Spondyloarthritis Research Consortium of Canada scores showed a trend of improvement during the study period.
Similarly, Williams and Cavanagh [ 91 ] showed a trend, although nonsignificant, towards less vertical oscillation and better RE.
The use of HAART showed a trend towards statistical significance for a better survival in patients with HIV-associated PBL [ 73 ].
Also, pitchers from warm weather areas underwent UCL reconstruction after having pitched significantly fewer seasons in MLB and showed a trend to undergo surgery at an earlier age than did pitchers from cold weather areas.
In the Phase II TOMORROW trial, treatment with 150 mg of nintedanib twice daily showed a trend to slow the decline in lung function and significantly decrease acute exacerbations in patients with IPF, while showing an acceptable safety profile.
In addition, DNMT1 and DNMT3A showed a trend to reversion of their decreased expression.
Unexpectedly, both mutants showed a trend of changes similar to WT mice for P21 up-regulated and down-regulated gene sets (Figure S7a, c in Additional file 9 ).
Due to safety concerns, there are few clinical trials involving smaller infants, Two recent trials involving 1200 infants with a birth weight of <1000 g showed a trend toward a decrease in the incidence of necrotizing enterocolitis (risk ratio 0.76 [95% CI 0.37 to 1.58]) ( 3 ).
Although CB 1 -KO mice showed a trend towards delayed transit, we did not observe a significant difference between groups (Figure 4 B).