Although DSS animals given only CNO showed a trend for upregulated MCC activity compared to home cage DSS animals, this did not reach significance (DSS + CNO: 1243 ± 249 vs DSS only: 374 ± 101 counts/mm 3 , p = 0.49; Fig. 3 B, examples in Fig. 3 D).
In this study, there was no significant difference in postoperative complications between the intervention and untreated groups, although the intervention group showed a trend toward fewer complications (32.8% vs. 41.9%, P=0.49).
The study comparing the combination therapy of carboplatin and gemcitabine with gemcitabine monotherapy showed a trend toward longer overall survival (OS) (6.7 months vs. 4.8 months, p = 0.49) and progression free survival (PFS) (4.1 months vs. 3.0 months, p = 0.36) in the combination therapy group, although the results were not statistically significant [ 13 ].
Only anti-CarP isotypes showed a trend that was no longer present after correction for multiple testing: one isotype versus two isotypes and three isotypes, respectively: 20% vs 12% ( p = 0.49) and 5% ( p = 0.02).
Compared to EGFR -TKIs, both CRT and RT combined with TKIs significantly improved PFS (P=0.02, 0.04, respectively), and showed a trend toward superior OS compared to EGFR -TKIs (P=0.49, 0.06, respectively).
Interestingly, patients in the en bloc resection group showed a trend to initiate radiotherapy more rapidly, thus without statistical significance (mean time to therapy: 28 days, vs. 40 days in the EI group), p = 0.49.
The anti-inflammatory miRNA-126-3p showed a trend towards downregulation in cytokine-sEVs (0.75 ± 0.56-fold change, p = 0.49), but this was not statistically significant ( Figure 5 a).
In the outer ring, the crystal area showed a trend toward reduction from baseline (0.247 ± 0.051 mm2) to one year (0.216 ± 0.046 mm2, P = 0.492) and two years (0.176 ± 0.050 mm2, P = 0.151), though these changes did not achieve statistical significance.
Patients with EBV-HLH showed a trend toward lower levels of IFN-γ in CD8 + T cells (28.23% vs. 20.10%, p = 0.494) and a higher granzyme B expression (9.94% vs . 15.60%, p = 0.418) ( Figure 3D ).
Expectedly, GABA (p=0.0517) showed a trend of decrease in AD post-mortem tissue ( Fig. 8 ) but glutamate levels were similar in AD and CN tissues (p=0.4986).
The size of PSDs in P20 boutons without mitochondria measured 0.012 ± 0.015 μm 3 , while P20 boutons with mitochondria showed a trend toward larger PSDs (0.011 ± 0.007 μm 3 ; p = 0.4994) compared to P20 boutons without mitochondria ( Figure 2 E).
We found that U-CLL cases showed a significantly more prominent proliferative response (48 ± 27% vs 17 ± 14% for M-CLL; p < 0.001); however, no significant differences were evident in terms of apoptosis, although U-CLL cases showed a trend for more homogeneous protection (25 ± 19 vs 38 ± 19 in U-CLL vs M-CLL cases; p = 0.5).
Results In a Spearman rank-order correlation hemi-matrix, of 55 paired combinations of the 11 biomarkers, 28 (51%) were significantly correlated among each other (p≤ 0.05), with the strongest association being retinol and tocopherols (r = 0.697, p<0.001), and 4 associations (9%) showed a trend (p> 0.5 to ≤ 0.10).
Results from 30,813 patients showed that, compared with aspirin, LMWH [odd ratio (OR) = 0.47, 95%CI: 0.29, 0.83], factor Xa inhibitors (OR = 0.50, 95%CI: 0.30, 0.89), and fondaparinux (OR = 0.32, 95%CI: 0.16, 0.64) significantly reduced the risk of VTE, but warfarin showed a trend towards a decreased risk (OR = 0.59, 95%CI: 0.36, 1.04; P = .50).
The SI of T1w, T2 w, and contrast-enhanced T1w images only showed a trend toward higher values for the treatment group ( p > 0.5, p > 0.3, and p > 0.4, respectively).
While the Kaplan–Meier survival analysis showed a trend toward poorer overall survival in F. nucleatum -high patients, the difference was not statistically significant ( p = 0.5).
After 3 days of storage, PPO activity in mung bean sprouts showed a trend of decreasing and then increasing with naringin concentration, which were all significantly lower compared to the control group ( p < 0.5).
On the whole, three cohorts of parents showed a trend ( P =0.5).
12 (52%); p = 0.27] and showed a trend toward more frequent use of the stent retriever alone [13 (42%) vs. 6 (26%); p = 0.51].
A subgroup analyses of BMI showed a trend in favor of inotersen to slow weight loss (least-squares mean difference, 0.50 points; P = 0.51) [ 14 ].
A comparison of grouped cases showed a trend emerging with borderline results (negative to weakly positive, P = 0.51; negative to strongly positive, P = 0.054; weakly positive to strongly positive, P = 0.17).
A comparison of the 2 strategies showed a trend in favor of the combined treatment in terms of mean symptom score reduction (P = 0.51) ( Fig. 2 ).
Patients with BRCA1/2 mutations also showed a trend towards worse survival outcomes compared to non-carriers after adjustment for systemic therapy (HR =1.49; 95% CI: 0.45–4.97; P=0.51) and surgical management of the breast (HR =1.63; 95% CI: 0.48–5.54; P=0.43), although this did not reach the level of significance.
PC1 scores from right V1 to V3 showed a trend towards predicting eye-looking PC2 scores (model uncorrected p = .51), motivating future study of this region in larger samples.
The Kaplan-Meier curve showed a trend toward lower outcome-free survival in patients with fQRS (71.3 vs. 82.6%; p=0.515, Figure 1A ).