showed a trendP = 0.107
L-centres showed a trend towards superior R1 rate (CRM+ and/or DRM+) with 4.4% versus 8.7% in R-centres and 8.4% in Ta-centres, P = 0.107.
L-centres showed a trend towards superior R1 rate (CRM+ and/or DRM+) with 4.4% versus 8.7% in R-centres and 8.4% in Ta-centres, P = 0.107.
The overall baseline microbial community composition, adjusted for age of sampling, age at RSV infection, gender, season of birth, and study site (permutation block), showed a trend toward a significant correlation with severity of disease (medically attended RSV infection, yes/no; PERMANOVA; R 2 = 0.8%, p value = 0.107).
Carrier children showed a trend ( p = 0.107, two-tailed Mann-Whitney test) towards carrying a higher number of minor eQTLs alleles (average = 4.3/person) than their carrier parents (average = 3.2/person) (Additional file 1 : Fig.
Analysis of overall survival (OS) showed a trend towards shorter OS in the HR patient cohort (HR vs LR days, p = .107; Supplementary Fig.
CXCR4 expression significantly increased at recurrence ( p = 0.029), and expression of its ligand CXCL12 showed a trend toward an increase ( p = 0.107).
Of note, glioblastoma individuals with SAO without surgery delay showed a trend to longer OS than the above-mentioned 14 cases with delayed surgery after SAO (13.0 vs 7.7 months, P = .1073).
HR for all cardiac events showed a trend in women with an HR of 1.021 (per 1‐ms increment in SD‐TPS, P =0.108) but no relation in men ( P =0.191).
These 9 negative results showed a trend toward longer time from symptom onset compared to the 29 rt-PCR assay–positive/antigen test–positive specimens (average, 4.4 vs 2.9 days, P = .108) [ 16 ].
After a median follow up duration of nine months, this study showed a trend for improved PFS (HR, 0.86; 97.58% CI: 0.69–1.06, P = 0.108) and OS (HR, 0.86; 97.54% CI: 0.65–1.13; P = 0.219); however, these results were not statistically significant.
In addition, 26% of patients in this study underwent reduced intensity conditioning (RIC) allogeneic stem cell transplantation, and they showed a trend of longer event-free survival and less transplant-related mortality in univariate analysis ( P = .108 and .107 resp.).
Assay trees at a 7‐m distance showed a trend (Table 2 ; p = .1080).
Unadjusted revision-free survival showed a trend favoring osteoarthritis compared to osteonecrosis (Fig. 1 ; p = 0.108).
In further exploring its relevance to the clinical diagnoses of dementia, Fisher’s exact tests revealed that clusters have a statistically significant association with the Braak staging of dementia ( P = 0.0025) and showed a trend of association with diagnoses of dementia by the NINCDS-ADRDA Alzheimer’s criteria ( P = 0.108), one of the most widely used criteria in the diagnosis of Alzheimer’s disease.
Hypomethylating agents are the most frequently used agents in the therapy of elderly AML in the US and Europe.[ 12 ] The DACO-016 study compared the efficacy and safety of decitabine (20 mg/m 2 /day for 5 days every 4-week) versus investigators choice (including LDAC 20 mg/m 2 /day for 10 days every 4-week or best supportive care) in 485 AML patients (median age 73 years) ineligible for cytotoxic chemotherapy.[ 12 , 13 ] The initial analysis showed a trend toward improved survival with decitabine (7.7 vs. 5.0 months; P = 0.108) that became significant ( P = 0.037) with further follow-up.
The effect of BR297 (2.5 mg/kg) showed a trend to lower potency in the early SI mice [+235%, t (26) = 1.66, p = 0.108].
Achieving pCR was associated with improved DFS, with a statistically significant difference in DFS curves between PCR and nonPCR cases ( p =0.008) ( Figure 2A ), and PCR patients also showed a trend toward better OS, but not statistically different ( p =0.108) ( Figure 3A ).
When adjusted by tumor size, NLR ≥ 2.49 just showed a trend to decrease CR rate (adjusted OR = 1.547; 95% CI, 0.909–2.631; P = 0.108).
The comparative analysis of foetal survival curves between infected groups showed a trend towards statistical significance ( P = 0.108) with a higher foetal median survival time in G2.
Overexpression of the PI3K/AKT/MTOR signature showed a trend toward improved response to everolimus (interaction P = 0.1085).
Although the AZA group showed a trend toward prolonged median OS (10.4 vs. 6.5 months; HR 0.85, P = 0.1087) without reaching the threshold for statistical significance, Europe and Japan granted approval based on survival benefits observed in sensitivity and domestic analyses [ 44 ].
This was not due to alterations in food intake as while SFN showed a trend towards decreasing food intake in C57BL/10 mice ( p = 0.1087), it had no impact on food intake in mdx mice ( Figure S2 ).
Effects of PTZ treatment on mRNA expression of epilepsy-related genes in the hippocampus, neocortex and prefrontal cortex PTZ treatment significantly upregulated Fos mRNA expression in neocortex ( P = 0.0001) and prefrontal cortex ( P = 0.0003; Table 1 ) whilst hippocampal Fos mRNA expression only showed a trend to increase ( P = 0.1089).
Finally, NLR showed a trend toward association with cfDNA levels (Fig. 5 C) ( r = 0.2360, p = 0.1089 ).
Furthermore, CAR showed a trend towards significant associations with 8MWT (adjusted R 2 = .226, R 2 change = .174 F = 2.312, P = .109, β = .452, P = .064) and 6MWT (adjusted R 2 = .236, R 2 change = .182 F = 2.387, P = .101, β =−.472, P = .058).
A model with Treatment, Age, and Sex as main effects showed a trend toward smaller infarcts with neutrophil depletion (β = − 8.0% hemisphere, p = 0.109), but this was not significant (model p = 0.096, R2 = 0.164).