In addition, the analysis of the prospectively documented values at study entry and after 1 year of observation showed a trend for higher CRP levels in B-cell low the group (median, 24.4 mg/l versus 9.2 mg/l [ P = 0.09], and 10.6 mg/l versus 5.0 mg/l [ P = 0.06], respectively) that reached significance after 2 and 4 years of observation (median, 16.4 mg/l versus 5.0 mg/l [ P = 0.01], and 14.0 mg/l versus 5.4 mg/l [ P = 0.01], respectively) (see Fig. 3a ).
Secondary analysis of country cohorts showed a trend toward benefit for the US cohort (hazard ratio, 0.36; 95% CI, .11–1.15; P = .09), which also had the highest risk of treatment failure.
When segmented according to IWRF classification, the highest functional capacity, H group (>1.5 points; n = 11) increased its [H 2 O 2 ] EBC per exercise ( p = 0.0029) and showed a trend for [NO 2 − ] EBC ( p = 0.09), while the lowest classification, L group (≤1.5 points; n = 5) showed a higher baseline concentration in both EBC markers with no changes per exercise.
Pairwise comparison between left and right ATR groups showed a trend for pleasant odors ( p = 0.09) but not for unpleasant odors ( p = 0.21).
The bolus samples showed similar patterns with increases in gene copies of enzymes such as sulfate reductase, fumarate reductase, nitrate reductase, and ammonia-forming nitrite reductase in HR cows, which showed a trend ( P < 0.09) compared to LR cows.
Additionally, translational evidence from fetal plasma showed a trend toward lower PlGF ( P =0.09) but no changes in VEGF circulating levels ( Figure 4D and 4F ).
In addition, Qanadli score, NT-proBNP, and troponin T showed a trend of being higher in the CDT plus anticoagulation group than in the anticoagulation group [42.50% (IQR, 35.00%, 50.00%) vs. 36.25% (IQR, 24.38%, 48.12%), P=0.09; 2,036.30 (IQR, 802.50, 3,984.00) vs. 1,033.45 (IQR, 379.75, 2,459.80) ng/L, P=0.07; 42.40 (IQR, 19.00, 68.00) vs. 23.31 (IQR, 9.28, 67.25) ng/L, P=0.07, respectively].
After adjustment mRS at day 90 still showed a trend for lower disability scores in the overlap group (3 IQR 1-5 vs. 3 IQR 1-6, p = 0.09).
Muscle from mitoquinone mesylate-treated old mice showed a trend toward a reduction ( P = 0.09) in OGG1 protein levels ( Fig. 3 C , right and lower), with no change in the levels of 8-OHdG ( Fig. 3 C , left).
Nevertheless, patients showed a trend for greater expression (t = 1.4, p = .09) of a brain signature of adult fibromyalgia pain (Lopez-Sola M et al., 2017).
Age showed a trend (F [1, 32] = 3.002; p = 0.09), but the other factors did not contribute to the model: Time since onset ( p = 0.95), sex ( p = 0.16), G1178A mutation ( p = 0.12).
Pyridoxine supplementation also showed a trend ( p < 0.09) towards a reduction in post-methionine load ΔtHcy.
Of the variants screened by TaqMan assay, only GSTP1 p.Val105Ile showed a trend toward a statistically significant frequency difference between cases and controls (p=0.09), suggesting it could be a possible modifier, but not a causal gene for MacTel.
Symptom Burden and Physical Functioning Pain scores (EORTC QLQ-C30) showed a trend toward improvement (mean: 30.00 ± 28.52 to 22.00 ± 23.12, p = 0.090), but the change was not statistically significant.
The K-ODI decreased from 27±5 to 21±7 and showed a trend toward improvement ( p =0.09).
Interestingly, activated T cells, defined by co-expression of CD38 and HLA-DR, showed a trend toward an increase in ICAHT patients compared to healthy controls (18% vs. 1.5%, p = 0.09) (Fig. 2 D).
The most hypermethylated tumors ( n = 29, subgroup of the CIMP-like tumors) showed a trend of worse patient survival ( P = 0.09) compared with the least hypermethylated ( n = 29, subgroup of the non-CIMP tumors) ( Figure 3C ).
Pearson regression showed that, across subjects, the effect size was positively correlated to SSRT (p = 0.04, r = 0.28) in PCD but not HC (p = 0.60), and the slopes of the regression lines showed a trend difference between PCD and HC (p = 0.09; Zar, 1999 ).
Individual components of the NAS score showed a trend to greater steatosis (2.7 versus 2.2, p = 0.09), no difference in hepatocyte ballooning (1.1 versus 0.7, p>0.2) and a significant increase in lobular inflammation (0.9±0.3 versus 0.3±0.2, p<0.05, Fig 2C ).
Overall sham mouse transitions showed a trend toward varying with dpo ( F (1.5,8.8) = 3.5, p = 0.09, one-way RM ANOVA).
Univariate analysis showed a trend towards increased risk of e-irAEs for women (OR, 1.39; 95% CI, 0.95–2.02; p = 0.09), although it was not statistically significant in multivariate analysis ( p = 0.8).
In the ICI plus chemotherapy group, the high PNI group showed a trend toward longer PFS than the low PNI group [median 7.9 months (95% CI 4.2-9.5 months) versus 3.9 months (95% CI 2.7-8.1 months), P = 0.09; Figure 3 A], though not statistically significant.
Notably, frontline treatment with CPX-351 showed a trend toward inferior OS compared with Ven-HMA (HR 1.3 95% CI 0.9–1.8, p = 0.09, Supplemental Fig. 4).
Survivors showed a trend toward lower initial lactate levels in comparison to non-survivors (4.0 [2.6–6.3] mmol/L vs. 7.5 [2.8–12] mmol/L; P = 0.09).
Self-reported alcohol craving Self-reported DAQ alcohol craving showed a trend for a main effect of time (F 2,58 = 2.5, p = 0.09, η 2 = 0.08), which was largely due to reductions in DAQ scores in the KD group (F 2,32 = 3.2, p = 0.056, η 2 = 0.17), but not the SA group (F 2,26 = 0.45, p = 0.64, η 2 = 0.03).