Ex vivo drug treatment results for the anti-CD38 antibody that were obtained clinically showed a trend toward a significant correlation with the re-treatment clinical response ( R = 0.59; P = .09; Figure 4 B) despite cell number limitations preventing analysis of the other drugs the patients received in their treatment combinations.
Positive cases for p-STAT1, however, showed a trend toward a worse OS compared to the negative ones (26.4 vs. 45.1 months, HR 1.5, [95%CI 0.9–2.4], p = 0.09).
Additionally, the Shannon index showed a trend toward increase ( p = 0.09), suggesting a potential shift in both richness and evenness.
reported that in patients with less than three distant metastases, TRT significantly improved the PFS (HR 2.02, P=0.003) and also showed a trend of improving OS (HR 1.55, P=0.09).
Nevertheless, patients that received a total absolute number of MNCs above the median (64x108 cells) showed a trend towards a higher response rate (75% vs 61%, p=0.09).
In addition to assessing statin-induced improvements in AA outcome after surgery, Randall et al [ 10 ] analyzed the impact of statins and antiplatelet therapy in patients who received AAA repair, elective carotid endarterectomy, carotid stenting, and suprainguinal and infrainguinal bypass from 2005 to 2012 in New England and found that patients who used antiplatelet and statin therapy preoperatively showed a trend towards lower 30-day mortality (odds ratio, 0.75; 95% CI, 0.5–1.05; P = .09).
WB inoculum recipients showed a trend of greater distance in microbial community structure to Sow ( P = 0.09) and Control ( P = 0.09) piglets than to the Mix group ( P = 0.73).
The dorsal attention network showed a trend toward greater value for reappraisal relative to passive observation of negative images ( d = 0.15, P = .09).
When mice reached the end of the open arm in the EPM, the GCaMP7s signal in the NaCl-C57-SI group showed a trend toward a higher AUC compared to the OXT-C57-SI group ( P = 0.09, Fig. 6C ).
While the expression of COL2A1 only showed a trend towards lower expression (FD = −17.2, P = 9.0 × 10 −2 ), significantly lower levels of matrix gene ACAN (FD = −21.8, P = 1.1 × 10 −2 ) and chondrogenic transcription factor SOX9 (FD = −3.9, P = 2.6 × 10 −2 ) were expressed in hiMSC-derived neo-cartilage compared to that from hBMSCs.
Compared with the FLO group, the FLOT group showed a trend towards an improved median PFS (21.1 vs 12.0 months; P = 0.09).
The KOOS showed a trend toward improved scores in group NS at year 1 ( P = .09) compared with group PS, but no further difference was seen between the groups.
The only treatment effect detected in the current trial was in systolic blood pressure, although the results showed a trend towards an improvement in SF‐36 bodily pain scores ( p = 0.09, ƞ 2 = 0.05) in the DHA group.
Although this group showed a trend for decreased fecal water content ( P = 0.09; Fig. 1C ), and slightly increased total bacterial load in the jejunum ( P = 0.09; Fig. 1D ) and ileum ( P < 0.05; Fig. 1E ), overall GI function seemed to be improved due to the strength of the effect on GI transit.
Here, male DG piglets showed significantly lower MR mRNA expression ( p < 0.01) and male DA piglets showed a trend towards lower MR mRNA expression ( p = 0.09) compared to male C piglets.
The MCV levels showed a trend toward statistical significance (P = 0.09), although other markers of hemolysis were not significant.
Other Th2-associated cytokines, notably IL-13, showed a trend toward elevation in allergic patients (10.52 pg/mL vs. 4.37 pg/mL, p = 0.09), though did not reach statistical significance.
While high TGFBR2 expression showed a trend towards poorer overall survival ( p = 0.09), it was a significant predictor of worse disease-free survival ( p = 0.0063) (Supplemental Figure S4A, B).
Self-reported alcohol craving Self-reported DAQ alcohol craving showed a trend for a main effect of time (F 2,58 = 2.5, p = 0.09, η 2 = 0.08), which was largely due to reductions in DAQ scores in the KD group (F 2,32 = 3.2, p = 0.056, η 2 = 0.17), but not the SA group (F 2,26 = 0.45, p = 0.64, η 2 = 0.03).
None of the differences between these groups reached statistical significance, although patients who underwent labral debridement alone showed a trend toward increased OA progression ( P = .09).
75.0 ± 6.7 mg/d l , P <0.05) and the ALB level showed a trend to be lower after treatment (2.63 ± 0.11 vs. 2.79 ± 0.09 g/d l , P =0.09) than before treatment ( Fig. 1 ).
The analysis also showed a trend toward a possible association between persistent headache and depressive symptoms (univariate analysis with an OR of 8.000 [range: 0.725–88.226]; p = 0.090).
RBM3 overexpression showed a trend toward the absence of lymphovascular invasion ( P = 0.09).
The exposure 2 group showed a trend to higher total PTB < 37 weeks compared with the pre-pandemic group (70.3% vs 67.1%; aRR 1.05 95% CI 0.98–1.10, p = 0.09) (Supplementary Table 3 ).
Targeted therapy before the presence of BM showed a trend towards significantly worse IPFS in univariate analysis but had a very wide confidence interval (HR 3.15; 95% CI: 0.81–15.23; p = 0.09).