However, Weighted Unifrac distance (panel C) showed a trend toward distinct clusters between HC and TSD (raw p -value = 0.035, adj p -value = 0.105) and to a lesser extent between HC and EPI (raw p -value = 0.074, adj p -value = 0.111).
Only endometrioid histology compared with non-endometrioid histology showed a trend to better OS (HR = 0.09, P = 0.035) (Table 2 ).
DRGs treated with human bevacizumab + FUS (nDRGs = 12; voxel: 98.2 ± 43.7; diameter: 0.86 ± 0.14 mm) showed a trend to being smaller ( p = 0.035) than those receiving human bevacizumab alone (nDRGs = 24; voxel: 144.8 ± 72.1; diameter: 1.02 ± 0.17 mm).
Of note, although rs10484561 showed a trend towards association in DLBCL in SF1 (trend p -value=3.58×10 -2 ), we did not observe markedly significant associations between the MHC region with risk of CLL/SLL or DLBCL ( Supplementary Fig. 5 ), which suggests that the influence of MHC genetic variation differs by NHL subtype.
Dunn’s post hoc test revealed that the Shannon diversity was significantly higher, and Chao1 species richness indices showed a trend toward higher in PN samples than in PD samples (adjusted p = 0.0358 and 0.0598, respectively).
Atp1a3 +/D801Y males showed a trend to lower weights only above 4 months of age; linear regression analysis found a significant difference ( p = 0.036; Fig. 1 B ).
In figure 4 c , co-registered measurements from the region of the fibrous cap ( n = 24) within diseased tissue sections were added to the dataset of the healthy group ( figure 3 ) which showed a trend towards a positive correlation between Young's modulus and collagen fibre density (Pearson's ρ = 0.53, p = 0.036).
Within the opioid-FM group, higher pain sensitivity to heat (i.e., lower sensitivity-adjusted temperatures) showed a trend relationship with higher opioid dosage ( r = −0.45, p = 0.036), potentially reflective of opioid-related hyperalgesia.
Hence, the comparison between the PPMS and SPMS showed a trend similar to the differences observed between the controls and PPMS groups for Mg, Cu, and Pb ( p = 0.036, 0.03, and 0.34, respectively).
In multivariate Cox regression analysis, including age, histological grade, tumor size and lymph node status, the macroH2A1.1/macroH2A1 mRNA ratio showed a trend as an independent predictor (HR 3.457, 95%CI 1.087 to 10.990, p = 0.036 ) ( Fig.5B ).
Runners with the D polymorphism (I/D and D/D) showed a trend of better performance in the 100-km ultra-marathon (measured by completion time in minutes, P = .036).
At day 37, only body length significantly differed across canopy types ( p < .001), although tail depth also showed a trend for differences across canopy type ( p < .036; Table S2 ).
The patients in the experimental group also showed a trend of decreasing TBil levels when compared with patients in the control group ( p = 0.036).
Treatment with carboplatin and paclitaxel showed a trend towards increasing the risk of complications (OR=1.926, 95% CI: 1.045–3.551, P=0.036).
In the advanced-stage diseases, low cytoplasmic phospho-p38 was significantly associated with present residual tumor and showed a trend toward stage IV disease ( p =0.036 and 0.073, respectively; Table 4 ).
Notably, the posterior group showed a trend of lateral foot pressure surpassing the ACDF group at 2 years (59.47% vs. 58.15%, P = 0.036).
At age 3 months, microglia of rTg4510 mice showed a trend toward decreases in Mmp2 (p = 0.0363) and Mmp9 (p = 0.0124) mRNA levels and an increase in Mmp14 mRNA level (p = 0.0341) compared to non-Tg mice as examined by Student’s t test with Bonferroni’s correction (N = three mice in each genotype; Figure 5 E).
The ANOVA for ESR1 test showed a significant difference between age/sex groups (F 5,23 = 2.882; p = 0.036) while the post hoc Tukey tests only showed a trend of slightly higher expression in the oldest males compared to the youngest males (adjusted p = 0.037; Figure 2 ) while its expression was comparable among other comparisons (adjusted p > 0.128; Figure 2 ).
The Jonckheere–Terpstra test showed a trend toward decreasing OT with calendar year on the left side ( p = 0.037) (surgeon’s non-dominant side), but not on the right ( p = 0.795).
Compared with healthy controls (median 5.99 AU), AGEs showed a trend in impaired glucose tolerance (7.22 AU; Cohen’s d = 0.425; uncorrected p = .037, corrected p = .094), significant increases in uncomplicated diabetes (9.81 AU; d = 1.027, p < .001) and complicated diabetes (13.35 AU; d = 1.540, p < .001), with no elevation in isolated hyperlipidaemia (5.86 AU; p = .987).
Additionally, hormone replacement therapy use showed a trend toward better delayed recall performance ( β = .58, SE = .27, p = .037, FDR-corrected p = .495), suggesting potential cognitive benefits.
Before PSM, radiotherapy showed a trend toward white race ( p = 0.037), high grade ( p = 0.017), large tumor size ( p = 0.010), positive nodal metastasis ( p = 0.021), advanced stage ( p < 0.001) and chemotherapy ( p = 0.008) ( Table 3 ).
Participants in the Q3 also showed a trend toward risk reduction (OR 0.57, 95% CI 0.34–0.97, p = 0.037).
ARHGEF18 showed a nominally significant downregulation (i.e., higher Ct values) in cases ( p = 0.037), and SRXN1 showed a trend towards downregulation in cases ( p = 0.056) compared with the combined control group.
Furthermore, MK-7 supplementation showed a trend regarding distensibility (pre/peri −4.9 ± 21.8; post +2.8 ± 30.8; p = 0.037) and compliance (pre/peri −7.4 ± 21.4; post +2.2 ± 30.8, p = 0.020).