An analysis comparing PFS by first-line therapy choice across KRAS variants showed a trend toward improved PFS with first-line fluorouracil-based therapy versus gemcitabine-based therapy for G12R (12.17 v 9.9 months; HR, 1.73 [95% CI, 1.05 to 2.84]; P = .0305) and the opposite trend with reduced PFS with first-line fluorouracil-based therapy for Q61 (3.13 v 5.6 months; HR, 0.46 [95% CI, 0.21 to 0.99]; P = .0479; Data Supplement, Table S2).
2.28), which had a lower mutational burden, and the PR patient showed a trend toward increased mutations during therapies ( Figure 3C and Supplemental Figure 3B , Kruskal-Wallis rank-sum test, P = 0.031).
Adjusted linear regression showed a trend for an association between longer DD and a greater sNfL z -score ( B = 0.35; p = 0.031; adjusted p [5] = 0.16); however, Spearman’s correlation was not significant (rho = 0.18; p = 0.078; n = 98) ( Figures 2 – 4 ).
That is, RTs for T2 with angry face distractors were significantly slower than those of T-baseline [MD = 19.6 ms, t (30) = 3.75, P = 0.001], and RTs for T3 with angry face distractor showed a trend level to significant when compared to those of T-baseline [MD = 8.9 ms, t (30) = 2.26, P = 0.031], suggesting significant attentional dwelling effects to the task-irrelevant angry face distractor in the SAD group ( Figure 1B ).
Neutrophils from treatment naïve AQP4 + NMOSD patients also showed a trend towards impaired cell death in response to PMA compared to their corresponding HC (Fig. 1 D; Live; p = 0.031; L.A./NETosis; n = 6 ; p = 0.062), possibly excluding a potential effect of therapies on the observed impaired response of neutrophils to PMA.
Variants in genes that cause EDS or EDS‐like phenotypes such as SLC39A13 , B4GALT7 , COL3A1 , COL5A1 , and COL5A2 showed a trend of approximately twofold increased frequency in cases compared with controls ( p = 0.031) (Table 2 ).
Finally, the Univariate Hazard Cox regression analysis showed a trend that impact of CXCR4 tumor expression (HR 0.49; 95CI 0.25 - 0.93; p = 0.031), the presence of residual disease >2cm (HR 3.67; 95CI 1.62 - 8.31; p = 0.002) as well as the number of chemotherapy cycles (HR 1.28; 95CI 1.05 - 1.55; p = 0.013) on RFS (Table 5 ).
Model 5 showed a trend of a significantly weaker association (p=0.031) for men.
Analysis of a subset of pts with cytogenetic data showed a trend towards lower baseline sBCMA levels in the standard-risk group (n=18) vs the high-risk group (n=42; p=0.032).
Correlations Correlation analysis showed a trend for an inverse correlation between map area asymmetry index and NHPT asymmetry index (ρ = -0.44; p = 0.032) ( Fig 6A , Table 4 ).
In the current study, we found that the rs3745453 showed a trend association with T2DM ( p = .032, OR = 0.837; 95% CI: 0.711–0.985); however, the rs3745453 showed no associated with T2DM after Bonferroni correction.
The left amygdala showed a trend for an interaction effect between Target Gender × Perceiver Gender, b = 0.268, SE = 0.124, CI 95% = [0.026, 0.510], t (189) = 2.167, p = 0.032.
PP 1 scores showed a trend for an effect of both sex [ F (1,20) = 5.30, p = 0.032, partial η 2 = 0.210] and speed [ F (1,20) = 4.80, p = 0.041, partial η 2 = 0.193] but did not reach the adjusted significance level.
The A allele of rs16944 also showed a trend towards association with schizophrenia in female subjects (odds ratio 1.26, 95% CI 1.02 to 1.56, P = 0.032).
13.5% in Q1, p < 0.001), and alcohol consumption patterns showed a trend towards higher consumption in the lower LDL/HDL ratio groups ( p = 0.032).
Pediatric-infratentorial group showed a trend of poor prognosis compared to adult-spinal cord group in terms of PFS ( p =0.032) ( Fig. 1B ).
Chemotherapy in addition to RT showed a trend for better DSS ( p = 0.032) but was not significant following Bonferroni correction.
Patients treated with primary (chemo)radiation showed a trend towards reduced skeletal muscle mass as compared to those treated postoperatively with 60.1% vs. 46.4% of sarcopenic patients for L3MA ( p = 0.032) and 55.7% vs. 43.3% for L3MI ( p = 0.059) ( Table 1 ).
Infants of SCZ mothers showed a trend towards less attentiveness ( p = 0.032) compared to the infants of MDD mothers.
However, participants with GG genotypes showed a trend toward better performance in the visuospatial function compared with the AA + AG genotypes ( p = 0.032).
The inbreeding coefficient ( F IS ) also showed a trend of decreasing from south to north for the nuclear microsatellite markers: r = −0.3738, p = 0.0326.
For searching fixations, however, context showed a trend indicating an effect on duration, F (1, 16) = 5.46, p = 0.033, η G 2 = 0.13, and there was a significant effect of epoch, F (2.69, 43.02) = 5.73, ε GG = 0.896, p = 0.003, η G 2 = 0.022, but no interaction, F (1.91, 30.58) = 5.73, ε GG = 0.896, p = 0.307.
The DMN and VAN also showed a trend of increased IntraNC (DMN: p = .033; VAN: p = .011), but these results failed to reach significance once corrected for multiple comparisons.
Conversely, in the thalamus, while preclinical scrapie-affected animals showed a trend towards upregulation of SPP1 , a significant upregulation ( p -value = 0.033) was evident in the clinical stage of the disease, compared to healthy controls.
Participants with hypoxic burden ≥42%min·h −1 showed a trend towards higher likelihood of significant decline in phonemic fluency (OR 2.26, p=0.033, according to Model 3) ( supplementary tables S10 and S11 ).