Using multiple meta-regression, the mean duration of illness showed a trend towards explaining this residual heterogeneity ( p = 0.0799, I 2 = 30.6%), whereas CPZ scores did not ( p = 0.2035) (see Supplementary Fig. 22 for bubble plot; Supplementary Table 13A, B for results).
The cardiac expression of CD68, a valuable macrophage marker in the histochemical analysis of inflamed tissues, 16 showed a trend toward an increase in HFD-fed mice in comparison to NFD-fed mice (p = 0.08), although dotinurad did not reduce it ( Figure S1 A).
The EUK-189 treatment improved performance on a rotarod and showed a trend towards prolonged life span (p = 0.08) ( Browne et al. 2004 ).
In contrast, PCB-treated Ahr d _Cyp1a2 (+/+) mice showed a trend ( p = 0.08) toward increased ASR.
Pro-apoptotic BCL2 associated X protein ( Bax ) had significantly increased expression in ovaries from offspring originating from PCEtOH-exposed pregnancies, while the pro-survival B cell leukemia/lymphoma 2 ( Bcl2 ) gene showed a trend ( p < 0.08) for increased expression.
Although the association was not replicated in two additional samples, it showed a trend ( P =0.08) with a related sensation-seeking scale.
Patients with ESR1 PvuII wt/wt genotype and at least one UGT2B15 wt allele had a worse DFS ( P =0.03) and showed a trend towards decreased Os ( P =0.08) in comparison to patients with ESR1 PvuII wt/vt or vt/vt genotype and UGT2B15 *2/*2 genotype.
Longer duration of sleep on actigraphy showed a trend for a correlation with higher scores on the Pittsburgh Sleep Quality (p = .08) but not on the Epworth Sleepiness Scale.
Hypoperfusion and organ dysfunction Significant differences were found in SjvO 2 , where post hoc analyses showed that group Prot-5h decreased more than the control group (p<0.05), whereas the Prot-7h group and the control group only showed a trend towards a difference (p=0.08) ( Table 4 ).
HER2+/HR− tumors showed a trend toward significantly higher TIL levels compared to HR+ tumors (mean 14.3 vs 11.9, p = 0.08).
In our meta-analysis, MPR was found to be significantly higher in females than in males, with an odds ratio (OR) of 1.82 (95% CI 1.13–2.93; p = 0.01), while pCR showed a trend to be more favorable in females than in males, but the OR of 1.62 was not statistically significant (95% CI 0.97–2.75; p = 0.08).
On the contrary, this parameter showed a trend to increase in the control group, with a median increment of 3.7% ( P = 0.08). 3.2.
Also, a significant difference in food intake was observed between the AG and UAG treated groups, while UAG noticeably reduced the appetitive response to AG when given in combination, although this effect only showed a trend ( Fig. 1 ; AG+UAG treatment, 4.1 g±0.56, p = 0.08).
Spectral analysis showed a trend toward an increased low-frequency to high-frequency ratio in patients (p = 0.08) suggesting sympathetic predominance.
Despite this fairly similar frequency in tumorigenesis in the spleen, a detailed analysis of abdominal non-lymphoid organs revealed that ZKO EBV infected animals showed a trend to reduced numbers of lymphomas in the liver (p = 0.08, Figure 2E ).
84.3% ( P = 0.61)], pooled graft stenosis and occlusion rates showed a trend to be higher in the MIDCAB group (10.5% vs. 6.4%, P = 0.08).
Findings were confirmed by the MADRS suicide item (r = .55, P = .02) and showed a trend on the SSI-5 (r = .41, P = .08).
Animals treated with RGB+KA also had steady GluR1 levels at this time; however, the ventral granule cell layer (VGCL) showed a trend of decline at 87.9 ± 7.2% of the control ( p =0.08).
5a ), and these participants also showed a trend towards shorter OS (median 15 versus 28 months; HR 2.0, 95% CI 0.88–4.64, P = 0.08) (Supplementary Fig. 5b ).
Additionally, the activity of ALAT showed a trend to be increased in DOX compared to MTX ( p = 0.08), despite no significant differences were found when comparing both groups with CTRL.
(3) Comparison of BD patients during their acute phase with controls showed a trend ( p = 0.08) towards lower dorsolateral prefrontal cortex (dlPFC) activation.
IFN-γ-concentrations showed a trend (combination vs. mNOX-E36, p = 0.08; combination vs.
1.9 ± 1.0, p = 0.302); however, a sub-analysis including only 16 patients with moderate to severe tricuspid regurgitation (TR ≥ 2), showed a trend in reduction of TR grade after MitraClip (2.9 ± 0.9 vs. 2.4 ± 1.0, p = 0.08).
As expected, DSS performance decreased from early to late adulthood ( t = -3.99, p < .01), whereas performance on the Spot-a-Word showed a trend for an increase with age ( Z = 1.72, p = .08).
Moreover, in GDM-HBC a higher percentage of cells was positive for M1 markers CD80 and CD40, but these increases did not reach significance (Table 3 ); however, the M1 marker CD86 (Figures 4 D,H) showed a trend toward increased levels in GDM ( p = 0.08; Table 3 ).