In their preceding study on 109 patients that were part of the mixed-race cohort, the same group had reported that carriers of a CYP2C8 *3 variant (defined as a c.1196 G-allele and/or c.416 A-allele) showed a trend towards a higher risk of grade ⩾3 peripheral neuropathy ( P =0.075) ( Hertz et al , 2012 ).
Surgical delay also showed a trend toward statistical significance as a predictive factor (adjusted OR = 1.04, 95%CI = 0.99–1.08, p = 0.075) ( Table 3 ). 3.4.
After accounting for patient demographic and clinical characteristics, the multivariable CPH model showed that increased clonality showed a trend toward decreased OS (HR = 2.79 with 95% CI [0.90, 8.66], p = 0.075), though not statistically significant.
( 34 ), in the study including 55% squamous cell lung cancers, showed a trend for poorer OS in subjects with larger volume reduction ratio (VRR) (HR =1.89; P=0.075).
Among patients with complete NOTCH1 and IGHV data (n=225), NOTCH1 m showed a trend toward worse survival in IGHV-mutated patients (HR=3.26, 95% CI: 0.89–11.94, p=0.075) but not in IGHV-unmutated patients (HR=1.29, 95% CI: 0.63–2.65, p=0.49).
Although not significant, WSLV NS1 IHC staining in the rSA999 group showed a trend to be higher than in the SAH177 group ( p = 0.075, Figure 5 B). 3.7.
However, sarcopenia patients showed a trend towards a lower OS than non-sarcopenia patients, with borderline significance (median 38.7 vs 57.3 months, p = 0.075).
Across participants in the Vertex group, mean pre-intrusion activation predicted the total number of intrusions recorded over the subsequent week for MFG ( r = 0.614, p = 0.004; Figure 4c ) and showed a trend for OVC ( r = 0.407, p = 0.075).
Analgesic medication use was not significantly associated with any caregiver burden dimension (all p > 0.40), but showed a trend toward higher PDQ-39 bodily discomfort scores (median 79.17 vs. 50.00, p = 0.075). 3.4.
Analysis of the Effect of ITG on Hearing Regarding hearing as shown in Table 4 , at the time of inclusion, PTA was slightly lower in patients in group 0 than in those in group 1 and showed a trend toward significance when compared with group 2 ( p = 0.075; Cohen's D = 0,33).
Time contrasts showed a trend decrease overall between baseline and end of ECT ( p = 0.075) and a significant increase between the end of ECT and 4-month follow-up ( p = 0.002).
Our study revealed HER2 CN-high patients showed a trend of intestinal-type GA predominant ( p = 0.075) and older age ( p = 0.07).
The analysis showed a trend towards significantly positive correlation between the two variables ( r = 0.430, p = 0.075).
Additionally, baseline carcinoembryonic antigen (CEA) levels were significantly associated with CCCA at T1 (Figure 3F ), and histological grade showed a trend toward association ( p = 0.075; Figure 3E ).
This gene is moderately expressed in the bovine mammary gland and also showed a trend (p = 0.075) to correlate to CHL_milk concentration (Table S4c ).
Furthermore, while Q14 and Q15 showed a trend to mediate higher calcium influx ( p = 0.075 and p = 0.085, respectively), Q16 exhibited a significant ( p ≤ 0.001) higher calcium mobilization when compared to MK-0677 (see Figure 4 A).
3.7 Clinical confounders DMN deactivation showed a trend association with medication dosage in ToL ( t = 1.9, p = 0.075, η p 2 = 0.12), but not in SWM ( t = 0.1, p = 0.910), indicating a tendency for decreased activation with increased medication use in ToL.
However, a further analysis that examined total recall across set lengths 3 to 5 revealed a main effect of list length that remained significant, F (2, 196) = 4.266, p = .015, MSE = 0.152, η p 2 = .042, and which still showed a trend toward a reliable interaction with group, F (2, 196) = 2.622, p = .075, MSE = 0.152, η p 2 = .026.
The primary endpoint was the ARR which did not reach statistical significance, but showed a trend to reduction with laquinimod [Risk ratio (RR) = 0.823, 95% CI 0.664–1.020; P = 0.075].
Although higher tacrolimus levels showed a trend toward increased PTDM incidence (Fig. 4 ), the difference was not statistically significant when comparing levels of 5–7 ng/mL, 7–10 ng/mL, and > 10 ng/mL ( p = 0.075).
As for race, the prevalence of anemia was higher in Blacks and mulattos than in white individuals (p-value = 0.002).When public sanitation was analyzed, the elderly who did not have basic sanitation in their homes showed a trend towards an increased prevalence of anemia (p-value = 0.075).
Neurofilament H expression was slightly reduced on day 2 after footshock ( Figure 3C: t (10) = 2.422, p = 0.035), remained unchanged on day 28 but showed a trend towards a reduction on day 60 after footshock ( Figure 3C: t (21) = 1.873, p = 0.075), while both MAP-2 and GFAP expression levels were not significantly altered at any of the three time points analyzed ( Figure 3D, E , see Table 1 for summary of all tested proteins).
Histopathological aggressiveness features—perineural invasion (PNI; 73.0% in the entire cohort) and vascular invasion (VI; 62.6%)—were relatively evenly distributed, although PNI showed a trend toward a higher incidence in PB (81.8% vs. 63.5% in the PN; p = 0.075), which, however, did not reach significance after adjustment.
In men, repeated-measures analysis showed a trend toward a positive association between average Z and CBF ( r rm = 0.509, P = 0.075), but this association was not evident in the Δ-based Pearson correlations (Δ Z vs ΔCBF: r = 0.269, P = 0.158).
PPAR-α and Gro-α also showed a trend of overexpression in CRC, with p -values slightly above 0.05 ( p = 0.075 and 0.068, respectively).