Additionally, STR showed a trend toward poorer OS in patients with IC tumors (HR = 7.60, p = 0.070) ( Fig. 3 c) and in the LPFS, PFS, and OS of the overall population (HR = 2.49, p = 0.063, for LPFS; HR = 2.22, p = 0.097, for PFS; HR = 7.18, p = 0.079, for OS) ( Fig. 3 d–f).
Depression and belongingness showed a trend (depression: β=−0.28, t (485)=−1.85, P =0.07; d=0.10; belongingness: β=0.56, t (506)=1.72, P =0.09; d=0.06).
PHQ-9 scores, which were available for 20 patients, showed a trend toward lower mean scores in the transgender patient group (4.091 vs. 7.091, p = 0.07), although this was not statistically significant (Table 1 ).
In contrast, posterior (and middle) hippocampal encoding engagement showed a trend-level relationship with later true recognitions across age groups (effect of engagement: β=0.05, SE=0.03, Z = 1.81, p = 0.07) in a way that reliably varied by encoding condition (engagement × encoding condition interaction: β=0.06, SE=0.03, Z = 2.27, p = 0.02; no interactions with age group: both p > 0.77; Fig. 3 A ).
Higher EDSS_c showed a trend toward greater gains in 6MWT distance (β =+11.0 m per EDSS point; SE = 5.71; robust t = 1.93; p = 0.070; conventional p = 0.091).
It also showed a trend toward increasing the proportion of type I muscle fibers (+32 ± 17%, p = 0.07), suggesting that antioxidant supplementation (including vitamins C and E, zinc, and selenium) may benefit COPD patients during pulmonary rehabilitation.
Hospital characteristics Hospital-level data showed a trend toward more obese patients being treated in large-bed (bariatric) hospitals (34.8% vs. 21.2%, p = 0.07), though this did not reach statistical significance.
For epithelial barrier function, occludin showed a trend toward statistical significance ( p = 0.07), with highest expression in the BD group; it appeared lower in the HF group (trend p = 0.09), showing a possible disruption of barrier integrity in HF-fed mice.
Potential confounding factors Although iron deficiency’s potential impact on PROs was not analyzed due to the low prevalence of abnormal hemoglobin levels (4.5% of the cohort), patients receiving iron supplementation ( n = 53) showed a trend toward lower SF-36 mental scores (mean MCS, 42) than untreated patients ( n = 133; mean MCS, 45; P = .07).
While there was no significant difference in reducing overall disability compared to no thrombolysis, the effect estimate showed a trend favoring Tenecteplase (gOR 1.28, CI 0.98–1.67; p = 0.07; I 2 = 0%) ( Figure 3 ). 4.
Indeed, we saw that anti-β7 treated mice showed a trend towards decreased disease scores compared to anti-α4β7 treated mice ( p = 0.07) ( Figure 3 A), as well as improved weight gain compared to anti-α4β7 treated mice ( p = 0.18) ( Figure 3 B).
0.5%; p < 0.001) [ 80 ] A follow-up analysis of alendronate trials also showed a trend toward increased AF (1.5% vs. 1.0%; p = 0.07) [ 80 ].
The mOS was similar for all genotypes in the PANGEA cohort, while the non-PANGEA cohort showed a trend towards prolonged survival in the non-F/F subgroup (mOS 43.4 versus 23.1 months, P = 0.07; Figure 2 A-C; Table 2 ).
Analyses 14 days after reinfusion showed a trend (p=0.07) for higher total CD3+ counts with a median of 724x10 6 /L in responders compared to 182x10 6 /L in non-responders, count of CD3+ CAR cells with 105x10 6 /L and 14x10 6 /L (p=0.07) as well as CD3+/CD4+ cells with 291x10 6 /L and 70x10 6 /L, respectively, (p=0.10).
Non-compliance with follow-up showed a trend toward decreased survival ( P = 0.07).
Similarly, milk 3′SL showed a trend towards higher concentration in PDM-HF compared to PDM-LF ( p = 0.07).
Neutrophils showed a trend to increase in ELA groups (P < 0.07) ( Figure 10C ).
Among infection subtypes, bacteremia showed a trend toward association with DCI in univariate analysis (OR, 11.67; 95% CI, 0.79-171.71; P = 0.07), whereas pneumonia and urinary tract infection were not significantly associated with DCI.
Mean data calculated from the STED images showed a trend towards decreased TOM20 cluster size in MCT RV myocytes (0.027 ± 0.01 μm 2 ) relative to CON RV myocytes (0.034 ± 0.01 μm 2 , p = 0.07).
Long-term guselkumab use showed a trend toward reduced relapse risk (HR 0.55, 95% CI 0.28–1.06, p = 0.07), whereas no significant difference was observed for secukinumab.
MiR-204 expression showed a trend toward higher expression in the interstitium compared to that in the glomeruli in IgAN cases with stable disease (IgANnp) and in TMN ( P = 0.07 for both) ( Figure 6 ).
FNDC5 z-scores also showed a trend of inverse association with pThr181-tau immunoreactivity in the hippocampus (Pearson r = −0.30; p = 0.07) ( Figure 2G ).
Meta-analysis showed a trend for probiotic use to prolong PFS (HR: 0.585, 95% CI: 0.328–1.045, p = 0.070) and increase DCR (HR: 1.868, 95% CI: 0.890–3.922, p = 0.099), although it was of borderline statistical significance.
Length of VEM showed a trend to be shorter in patients experiencing complications compared to patients with no complications (8.8 ± 3.9 days vs 10.6 ± 4.9 days, p = 0.07).
At baseline in room air, Hcrt–SAP lesioned SHRs showed a trend for reduced MAP compared to IgG–SAP control SHRs in quiet wakefulness (Hcrt = 107.9 ± 1.9; IgG = 121.4 ± 11.1; p = 0.07) and a significant reduction in NREM sleep (Hcrt = 96.6 ± 4.5; IgG = 112.1 ± 12.3; p = 0.02).