A LEAD-2 sub-study followed up the LEAD trial in the same patient population in which liraglutide 1.8 mg showed a trend toward improving hepatic steatosis versus placebo (liver-to-spleen attenuation ratio: +0.10 vs. 0.00; p = 0.07) [ 26 ].
A proteasomal subunit in close proximity to the Rpn8-Rpn11 heterodimer is PSMD13 (Rpn9), which showed a trend towards upregulation (fold change = 4.2; p = 0.07).
The GWI + VNS sham group showed a trend ( P = .07, NS ) toward a reduced frequency of visits to the novel place object.
Interestingly, 4-months-old Fus ΔNLS/+ mice showed a trend towards longer interaction with the intruder mouse as compared with Fus +/+ mice ( p = 0.07) (Fig. 2a ), that was significant at 10 months of age (Fig. 2b ) and persisted until 22 months of age (Fig. 2c ).
IFITM3 rs34481144 A-allele showed a trend ( P = 0.07) for an increased risk of severity of COVID-19 (OR: 1.81, 95% CI: 0.95–3.43). 4.
Modified O’Driscoll scores at 4 weeks post-operatively showed a trend toward improvement in cartilage repair quality in the SDF-1 group relative to the empty control group (13 ± 8 vs . 3 ± 1; P = 0.07); however, the difference was not statistically significant.
The quantitative analysis of collagen protein using ELISA showed a trend ( p = 0.07, ANOVA) for an increased collagen I content in the NF‐treated diabetic wounds (Figure 2H ).
Further analysis on adequate occlusion post-procedure and on follow-up revealed that BAC treatment showed a trend towards better adequate occlusion rates post-procedure(76.5%) with p = 0.07 compared to 60.3, 54.2 and 16.7% for primary coiling, SAC and flow diversion, respectively ( Table 4 ).
In contrast, schizophrenia patients showed a trend toward reduced mean total power from Baseline to post-VHFS blocks (Post-1: p = 0.070; Post-2: p = 0.10; Post-3: p = 0.050).
The comparison of the two groups showed a trend towards an earlier occurrence of infection in patients with biliary complications (p=0.07, Table 2 ).
However, when very preterm adolescents with moderate-severe BPD were compared to very preterm ones without BPD, the first group showed a trend towards worse left ventricle function: less shortening fraction (37.5 ± 3.2% vs. 40.7 ± 4.9%, p = 0.07), less ejection fraction (68 ± 4.4% vs. 71.2 ± 5.4%, p = 0.06) and a greater E/E’ ratio (6.4 ± 0.8 vs. 4.9 ± 1.04, p = 0.01).
However, compared to high-RFI steers, low-RFI steers showed a trend towards reduced DMI (12.9 vs. 13.6 kg/d; P = 0.07) but ADG was similar for the two RFI groups.
Low TB was statistically significantly associated with a greater reduction in SALT at 6 and 9 months of treatment ( p < 0.05) and showed a trend towards statistical significance at 12 months ( p = 0.07).
In patients with ICDs, a non-negative TWA showed a trend toward higher risk for appropriate ICD shocks (HR=3.79, p=0.07).
Analysis demonstrated that participants classified as high iron consumers showed a trend of higher Hb levels (12.75 mg/dL ± 2.8 vs. 10.73 ± 3.5 mg/dL) when compared to their lower iron intake counterparts ( p = 0.07). 4.
Moreover, the presence of >30% TIL was seen only in patients who experienced a clinical benefit (25% vs 0%, p=0.22) and the tumors of patients who experienced a clinical benefit from therapy showed a trend towards greater TIL compared with those who lacked clinical benefit (27% vs 11%, p=0.07), suggesting TIL levels may serve as both a prognostic and possibly predictive biomarker, requiring further validation ( online supplemental figure 2 ).
The subgroup of non‐T2D patients showed a trend for a higher proportion of GLP‐1 expressing cells ( p = 0.07).
Results showed a trend that the BrainCheck composite score was positively correlated to subjective hearing [F (1, 294) =3.29, p =0.07], after adjusting for age at implantation, a demographic factor that negatively affected the subjective hearing [F (1, 294) =44.93, p <0.01].
In support of this, Pol II signals showed a trend of increase at two of these enhancers ( p = 0.07–0.08) in response to FC (Supplementary Fig. 7a-c ), which are consistent with the earlier findings 16 ; although the Pol II difference between WT and Top3β-KO mice was not significant.
In this present study, median values of IL-8 showed a trend of difference between baseline/control site and the nasal bridge after NIV-therapy (p = 0.07).
SP‐11 showed a trend toward attenuating the colonic hyperpermeability induced by PRS (0.95 ± 0.05 vs 0.71 ± 0.11 nmol/cm 2 /h, respectively, P = .07; Figure 3 ). 3.3 Gut transit After stress induction, colonic mean retention time significantly decreased in comparison with non‐stressed animals treated with saline (9.85 ± 0.65 vs 3.75 ± 0.52 hours, respectively, P < .01).
In the U-CARE Heart study that enrolled 239 patients with depression following ACS, internet-based CBT was comparable with the usual treatment in reducing depressive symptoms, but showed a trend for increased risk of CVD [HR, 1.8; 95% CI, 0.96–3.4; p = 0.07] [ 165 ].
In the Ang2 group, treatment with a combination of Ang2 siRNA + CS showed a trend toward decreased lung compliance ( p = 0.07) ( Figure 4B ) while in the CHOP group, treatment with CHOP siRNA + CS resulted in increased lung compliance than treatment with CHOP siRNA alone ( p = 0.05) ( Figure 4A ). miR34a Inh showed the best compliance with no significant difference in all the three groups (CS with ventilation, miR34a Inh with ventilation and miR34a Inh + CS with ventilation) studied ( Figure 4C ).
DHEA levels showed a trend towards being significantly higher in boys with more environment-related childhood adversity ( p = 0.07).
Furthermore, cl‐OPN/FL‐OPN showed a trend ( P =0.07; N=28; Wilcoxon matched‐pairs signed rank test) to be higher in plasma from the coronary sinus versus plasma from the radial artery, indicating that osteopontin might be cleaved locally in the pressure‐overloaded human heart.