showed a trendp = 0.0665
The combined total histopathology score also showed a trend towards being lower in the treated group ( p = 0.0665; Fig. 7D ).
The combined total histopathology score also showed a trend towards being lower in the treated group ( p = 0.0665; Fig. 7D ).
Monocytes also showed a trend toward a sex effect (p = 0.0666), with females tending to exhibit higher counts than males at 24 hpi (p = 0.1346) ( Supplementary Figure 4E ).
Plasma from AH-exposed mice showed a trend of reduced antioxidant reductive capacity relative to plasma from AC mice (Figure 4A ; P = 0.0667).
However, both TPC and TPcC showed a trend towards variation ( p = 0.0667), whereas DPPH radical scavenging activity did not show statistically significant variation ( p = 0.3333).
The expression of miR-132 showed a trend towards a negative correlation with MAG1 antibody level (r = -0.61, p = 0.0667, Fig 7B ) Discussion To provide insights into virulent strain-related severity of human toxoplasmosis, we established a chronic model of the virulent type I strain using outbred mice.
SV breakpoints were detected at a median of 0.5 per sample (range, 0–13) and showed a trend toward increased frequency in recurrent samples ( P = 0.0668, Mann–Whitney U test; Fig. 1D ), further supporting qualitative differences in genomic alteration patterns.
Female offspring from the SL group also showed a trend to higher glutaminase C protein levels ( p = 0.0669) in the hippocampus, although without alterations in vGLUT1 and PSD95 protein levels ( Figure 5 G–I).
Patients harbouring at least one TA ‐allele had a lower MELD (9 (8‐12) vs 10 (8‐13) points; P = .003) and showed a trend towards lower HVPG (16 ± 6 vs 17 ± 7 mmHg; P = .067).
Among patients with ALS or PDoed, those with EOL decision showed a trend toward a higher frequency of unconsciousness or limited consciousness than those without EOL decision ( p = 0.067).
Safety analysis of the trials showed a trend (p=0.067) toward more overall infections in the ETN-treated patients versus placebo in one of the trials, but not in the second one.
Patients with extranodal disease showed a trend for better PFS in the BV cohort with a HR of 0.65 (95% CI, 0.41-1.03; P = .067) but this was not significant.
Significant main effect differences between grads and non-grads were found for CK, Cl, DHEA-S and TCO2, while NE serum levels showed a trend by graduate status (p = 0.067) ( Table 2 ).
The relative expression of Gbp4 was significantly reduced (** P < 0.01), while Irgb6 and Gbp5 showed a trend toward reduction ( P = 0.067), but no change was observed in Ly6a or Zbp1 expression in infected IFN-γR −/− mice compared to wild-type (WT) controls ( Fig. 2A ).
Recipients of auto-HSCT with COVID-19 were older and showed a trend towards a higher incidence of arterial hypertension (28% vs 10%, p=0.067) without statistical differences in other comorbidities; active disease requiring treatment at COVID-19 diagnosis was more frequent in auto-HSCT recipients (65% vs. 21%, p<0.001).
Experiment 2: Adult morphology In adulthood, PA female pancreatic sections, compared to controls, showed a trend ( P = 0.067) towards reduced fraction of small islets, ranging from 100 to 1100 μm 2 in size (data not shown) and decreased islet counts ( P = 0.068; control 8.25 (±0.75); PA 6.11 (±0.74))/μm 2 ×10 −6 ) (data not shown).
Although not statistically significant, HXN-treated mice showed a trend toward a lower AUC ( Figure 2—figure supplement 1B , p=0.067).
Composite memory also showed a trend of reduction ( p = 0.067).
Consistently, ACE promoter methylation in vastus lateralis muscle was associated with habitual endurance exercise ( p < 0.001, η 2 = 0.059), being 0.220 points higher in the endurance exercising subjects, and showed a trend towards an interaction with the ACE I/D genotype ( p = 0.067, η 2 = 0.010).
CMV D+/R− serostatus showed a trend toward association with PjP (HR = 3.039, 95% CI: 0.927–9.964, p = 0.067).
After adjustment for age, sex, ABCD2 score, SBP, DBP, previous stroke, history of cardiovascular disease, eGFR, and hypercholesterolemia, an ACR greater than 1.5 mg/mmol predicted high‐risk patients (Cox proportional hazards: 3.5; 95% CI: 1.3–9.5; P = 0.01), significant ICA stenosis (Cox proportional hazard: 4.2; 95% CI: 1.14–15.7; P = 0.03), and showed a trend for the prediction of recurrent events (Cox proportional hazards: 4.1; 95% CI: .91–18.2; P = 0.067).
Renal function parameters showed a trend toward greater impairment in the concurrent amyloid deposition group, with higher creatinine (104 μmol/L (range, 41–133) vs. 77 μmol/L (range, 31–1037), p = 0.067) and lower eGFR (61.1 mL/min/1.73 m2 (range, 49.7–124.9) vs. 98.0 (range, 4.5–149.3), p = 0.054), although these differences did not reach statistical significance.
maenas showed a trend for avoidance of the male H. sanguineus treatment over the control (one-way ANOVA, F = 2.71, 2 d.f., p = 0.067, N = 721, Tukey post-hoc p = 0.068, p = 0.200, for H. sanguineus male and H. sanguineus female treatments, respectively).
Secondary analyses of the RT data showed a trend for a CI modality × timing condition interaction [ F (1,19) = 3.8, p = 0.067, η 2 = 0.17].
For OS, age (HR 1.66, 95% CI 1.098–2.524, P = 0.016), heart disease (HR 2.64, 95% CI 1.043–6.688, P = 0.040), and T-stage (HR 2.21, 95% CI 1.476–3.313, P < 0.001) were independent prognostic factors, while N-stage showed a trend ( P = 0.067) (Table 3 ).
Seizure frequency showed a trend toward reduction following ozone treatment (1.20 ± 0.20 vs. 0.70 ± 0.15; p = 0.067).