In ALL risk genotypes were defined as ETV6 _rs1573613 CC, PML _rs9479 GG, TLX1 _rs2742038 TT, ATM _rs227091 CC and CT, and IRF8 _rs10514611 TT (the latter two reached borderline significance in the analysis of individual SNPs).
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p=0.0509
In the literature
Finally, we tested whether age at diagnosis affected the slope of decline of C-peptide by adding an interaction term (model 4), and this effect reached borderline significance, indicating that older children had a less steep decline in C-peptide over time.
When analysis was performed on both shaved and unshaved mice ( n = 10) with the fur effect blocked, only two genes (Cd276 and Daglb) reached borderline significance at FDR = 0.049.
Among the IBD patients included in our study, the UC patients had a higher age (on average almost 10 years older), compared to the control group and CD patients, although the statistical significance of this difference reached borderline significance.
Even if the difference reached borderline significance only, application of a quantification tool might facilitate objective differentiation.
Although LD score regression analysis showed no statistically significant association between adiponectin and RA, it suggested a potential association as the p -value reached borderline significance.
For the first time, we found a possible association of FCN1 polymorphism with multiple myeloma: the genotype G/A-C/C-G/G (at positions −542, −144, and +6658, respectively) was more common among patients than among controls, although the difference only reached borderline significance.
The p ‐value for a treatment‐by‐sex interaction reached borderline significance for two of the three primary endpoints ( p for interaction 0.13, 0.30, and 0.104, respectively).
The results on COVID-19 related hospitalization and mortality upon hospitalization for COVID-19 infection also reached borderline significance.
This analysis of a patient collective, having undergone resection of brain metastases, did not confirm the relevance of hemodynamic parameters, as the mean intraoperative diastolic blood pressure only reached borderline significance.
After adjusting for multiple testing using the Benjamini and Hochberg FDR, 25 IgG Abs at the 3-month postinfusion time point reached borderline significance (FDR = 0.058).
CDC was independently predicted by child age at follow-up, and for CBSI, age reached borderline significance as a predictor.
Although this association only reached borderline significance, we suspect that it might be of importance given the relatively large effect size.
EVT + 0.0625 mg/kg TNK reached borderline significance, likely reflecting increased statistical power from pooling three underpowered direct-comparison studies ( Huang et al., 2025 ; Hu et al., 2025 ; Hou et al., 2025 ).
Two SNPs reached borderline significance (rs10832417-T, β = 0.547, FDR < 0.1; rs7103496, β = 0.676, FDR < 0.1).
In the univariate analysis, Mayo risk score (p = 0.02) and biliary candidiasis (p = 0.006) were associated with reduced survival, whereas presence of dominant stenosis and IBD reached borderline significance.
Mean intake of protein from dairy products was also higher among LCT heterozygotes and TT homozygotes, respectively, although this association only reached borderline significance.
For early treatment versus none, highly consistent, protective point estimates were also generated for most comparisons in adults and children, but failed to reach a statistical significance for IRP [possibly due to type II errors (sample size) although they reached borderline significance for ‘any pneumonia’ (all cases)].
A low PaO 2 /FiO 2 ratio was a significant mortality predictor in both groups, while HF was a significant mortality predictor in non-CCS patients and reached borderline significance only in CCS patients.
Although the 8q24 rs10090154T allele confers a 1.7-fold increase in PCA risk in a small case-control study set involving African Americans (85 cases and 149 disease-free men), this locus only reached borderline significance (OR = 1.69; 0.92-3.11).
In addition, other female genital cancer reached borderline significance (95%CI 0.98–1.96).