Barely Significant
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“practically significant”

1,559 sentences · 1,559 papers · 1,897 search hits before verification · confirmed specimen

Sighted at

p=0.06

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Based on power of 0.80 and alpha set at 0.05 (two-tailed), this sample size was adequately powered to detect a small effect size (Cohen’s d > 0.38) corresponding with what Ferguson (2009) classified as ‘minimal effect size representing a practically significant effect for social science data.’ Participants ( n = 175) were aged between 21 and 80 years old ( M = 37.13, SD = 12.69), and tended to be GPs/physicians (48.5%), clinical dieticians (21.7%), or medical students (9.7%), with small numbers of registrars, nurses, psychologists, and psychiatrists.
For each bioactivity end point ( xC 50 and K x ) and each split type (stratified and scaffold cluster), we conducted tests separately across models and across the selected performance and uncertainty metrics (RMSE, miscalibration area, NLL, CRPS, interval, sharpness). This dual-testing strategy ensured that conclusions did not depend on a single assumption about distributional form, and aligns with recent recommendations for practically significant model comparisons in molecular machine learning.