Mutations in TGFbIIR, which are nearly always found in microsatellite unstable tumours because of a coding mononucleotide repeat in the TGFbIIR gene ( Markowitz et al , 1995 ; Samowitz et al , 2002 ), are on the margin of significance, with P =0.035.
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There was no difference in average peak intensity in 22 positions, which included three peaks in which the differences were on the margin of significance (0.1 > p > 0.05).
When we compared the postprandial leptin levels between the HC and HF-meals, we found that men with normal body weight showed a tendency, which was on the margin of significance ( p = 0.05), to higher leptin concentrations 240 min after the HC-meal intake ( Figure 2 B).
The wild and transplanted diploids comparison was on the margin of significance ( p = 0.053).
The effect of niche was on the margin of significance in the linear model ( P = 0.056); a post hoc Tukey’s Honestly Significant Difference test found fermentation to be higher than the other categories (mean filamentous index of 14.29 compared to 13.01, 12.83, and 12.52 for lab, clinical, and plant, respectively).
A second measure in which participants sorted 20 emotion words into piles also showed that participants made fewer piles than controls—suggesting less differentiation—though the result was on the margin of significance ( p = 0.06).
One-way ANOVA demonstrates differences in the mean MoCA scores among genotypes on the margin of significance for both genetic variants ( p = 0.065 for LUZP2 and p = 0.069 for FBXO40).
The results were on the margin of significance: using Fisher's test (a test that supposes an affine relationship between variables), the value was 0.07 and the correlation coefficient, , was −0.185.
Concentrations of 7-DHC above the 95 th percentile (5.4 ng/mL, OR 2.4, 95% CI 1.6–3.6, adjusted- p <0.001) and desmosterol concentrations below the 5 th percentile (1.9 ng/mL, OR 1.9, 95% CI 1.2–2.9, adjusted- p 0.053) were associated with depressive symptoms of at least moderate severity, albeit the multiple hypothesis testing corrected p value for desmosterol was on the margin of significance.
The same effect on the margin of significance was revealed under disturbances before the morning fluctuations of diurnal geomagnetic variation on 14 September 2020 ( Table 1 ).
27.4 ± 6.0, p = 0.051) that remained on the margin of significance, reflecting the beneficial effect that group sessions may have not only in reducing depressive symptoms but also in improving self-esteem in this type of patients.
Increased conflict with parents (ARR = 1.84; 95% CI 1.14 to 2.98) and intimate partners (ARR = 2.68; 95% CI 1.35 to 5.31) remained significant after adjusting for sex, ethnicity and household income, and conflict with siblings was on the margin of significance (ARR = 1.63; 95% CI 0.95 to 2.81).
In the study by Goetzl et al., uterine rupture was more often preceded by an episode of hyperstimulation (defined as >5 contractions per 10 min, that resulted in reduced administration of oxytocin) compared with controls: 37.5 and 20.8 %, p = 0.05, which is on the margin of significance [ 23 ].
Those participants receiving counseling were on the margin of significance for being 29% less likely to experience monthly adherence <80% over 18 mo follow-up compared to those who received no counseling (hazard ratio [HR] 0.71; 95% CI 0.49–1.01; p = 0.055) ( Figure 3A ; K-M log-rank p = 0.053).
The differences are not powerful and on the margin of significance but might be due to subtle weakness.
ALDEx2 contains built‐in functions to allow researchers to identify features that are particularly sensitive to increasing values of gamma (i.e., those that were already on the margin of significance without accounting for even small amounts of scale uncertainty).
Secondly, some positive statistical findings were on the margin of significance, and they were also validated post hoc by logistic regression, but the efficacy was found to be weak.