Among older patients (50 years or more), those with highest level of education had higher rates of inappropriate use, although the p-value was of borderline significance.
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Furthermore, we observed a strong positive enrichment trend for pathways related to DNA synthesis and metabolism, including “Regulation of DNA Replication” (NES = 2.64), “Glycine, Serine and Threonine Metabolism” (NES = 2.64), and “Carbon Metabolism” (NES = 2.92), although the adjusted P -values for these pathways were of borderline significance (Fig. 7 G–I).
Results The association of NFRP classes with event-free survival (EFS) is of borderline significance in our adult T-ALL patients A total of 86 newly diagnosed adult T-cell acute lymphoblastic leukemia (T-ALL) were included in the present study (Table 1 and supp.
An association of borderline significance was observed for eye cancer (4.7, 1.0–25.0), and one of four patients with anal cancers were HIV positive (OR: 7.7, 0.6–93.0) (Table 2 ).
Results showed that the effect of telmisartan on the primary outcome was of borderline significance, probably because of an unexpectedly lower number of outcome events [5] .
The lower success rate in prior tobacco users could theoretically relate to wound healing or perfusion; this finding was of borderline significance and could have been related to the multitude of comparisons.
A trial of predischarge intravenous ferric carboxymaltose to patients who had been hospitalised with acute heart failure (AFFIRM-AHF)) suggested that treatment to 6 months might reduce the risk of recurrent hospitalisations for heart failure but not cardiovascular mortality when assessed at 52 weeks, although the effect on its primary endpoint, a composite of recurrent hospitalisations for heart failure and cardiovascular death, was of borderline significance. 6 A meta-analysis of seven randomised trials of patients with HFrEF and iron deficiency found that intravenous iron reduced the risk of hospitalisation for heart failure but was unable to demonstrate a reduction in cardiovascular mortality. 7 Major gaps in our knowledge remain, including the long-term benefits and safety of repeated administration of intravenous iron.
However, no significant association was observed between MAR score and low CC and only the NAR for magnesium was significant in the fully adjusted model for low CC; protein in g/kg body weight was of borderline significance.
For example, Berkey and colleagues report that every hour of self-reported daily PA in girls aged 9–14 is associated with a −0.0284 kg/m 2 smaller increase in BMI over a one-year period (the relationship was of borderline significance in boys) [ 21 ].
Fascin expression contributes to progression of human PDAC, but is only of borderline significance as a prognostic indicator, indicating that other factors contribute to recurrence and spread.
Although the difference between early and late recrudescence groups was not significant ( P = 0.06), the comparison was based on very small sample sizes ( n = 3 and n = 2), so the P value of borderline significance should not be interpreted as no difference in recrudescence time.
Of note, in the Caucasian population, the association was of borderline significance, which might be attributable to limited sample size of participants.
Other studies have examined associations between MPM risk and the pigmentation pathway by assessing variations in MC1R 18 – 20 and MITF 21 , as well as vitamin D synthesis among individuals exposed to high levels of sunlight in recreational activities 22 , although these results were of borderline significance.
Compared with luminal A cases, premenopausal luminal B cases were likely to be underweight (OR, 3.27; 95% CI, 0.88–11.39) or obese (≥25 kg/m 2 ; OR, 3.32; 95% CI, 0.98–10.81), yet this association was of borderline significance.
These associations remained significant after further adjustment for BMLs, except that the longitudinal association at the patellar site decreased in magnitude and became of borderline significance (Table 2 ).
assessing RT in the setting of oligometastatic brain metastasis found that the cumulative brain metastases volume was of borderline significance when examining intracranial control [ 8 ].
Clinical tumor size and invasive lobular carcinoma were of borderline significance.
Morbidity in the exposed cohort in relation to the unexposed cohort (external analysis) In the external analysis ( table 2 ), we observed a very small increase of borderline significance in all-disease risk among Chernobyl cleanup workers (RR=1.01; 95% CI 1.00 to 1.03).
In contrast, the change in D 3 Cr muscle mass/weight was moderately correlated with change in walking speed ( r = 0.33); the correlation between the change in D 3 Cr muscle mass and change in walking speed was of borderline significance ( r = 0.29) ( Table 4 ).
In the high IRI subgroup, there was still a slightly higher risk of diarrhoea in UGT1A1*1/*28 patients (OR=1.39, 95% CI: 0.97–1.98; P =0.07), of borderline significance.
There were also negative correlations of borderline significance between APOE-ε4 and APOE-ε2 for blood biochemistry, and between APOE-ε4 and familial risk for metabolic health traits.
The risk was of borderline significance for colorectal cancers (1.37, 95% CI 0.99–1.87) among siblings.
(1999) that mapped WSS at the rabbit aorta-coeliac junction.) In a subsequent statistical comparison ( Peiffer et al., 2013b ) of the WSS distributions with lesion patterns obtained in cholesterol-fed rabbits ( Cremers et al., 2011 ), the correlation was of borderline significance for immature animals and not significant for mature ones.
In ELSA, the overall association was of borderline significance ( P for overall = 0.058), and no significant non-linearity was observed ( P for non-linearity = 0.785).
On comparing the PAPR systems pairwise, the difference between PAPR B and PAPR C was of borderline significance, with PAPR C producing higher log reductions than PAPR B, and PAPR A between the other two.