“of borderline significance”

Indeed, the increased risk of MI in the VTE cohort compared with the control cohort in the first year was of borderline significance (adjusted RR: 1.6; 95% CI: 1.0–2.5).

At the multivariate analysis, pons location was an independent factor of improved FLP [HR 0.202 (95%CI 0.048–0.845); p = 0.02], while concurrent targeted therapy was of borderline significance [0.058, HR 0.139 (95% CI 0.0182–1.064].

( 9 )—increase of borderline significance.

uPA/PAI-1 and tumor grade were of borderline significance for OS.

18 A fourth prospective study based on Australian participants (38% premenopausal), suggested a positive association with fT4 of borderline significance (OR per unit increase = 1.07 (0.99–1.17)), but included a more limited number of cases (n = 100). 15 Although one prospective study (n = 61 cases) reported higher breast cancer risk among postmenopausal women with low fT4 concentrations, 19 a recent, large Mendelian Randomisation analysis combining

9.45 ± 6.2 ng/mL; p = 0.046) were elevated in the plaque group, although the difference in BMP-2 was of borderline significance ( Table 2 ).

Linear regression modelling identified all the same predictor variables, and in addition an association (of borderline significance) was observed between prior antibiotic and prednisone use and improved QoL [ Supplementary Table 2 ].

In non-surgically managed patients, waist circumference remained of borderline significance (HR 0.54, 95% CI 0.30–1.01).

Increased tumor size ( p = 0.01), presence of metastasis ( p < 0.001), presence of epithelioid cell morphology ( p = 0.008), involvement of iris ( p = 0.02), ciliary body involvement ( p = 0.02), absence of intrascleral location ( p = 0.02) and presence of extrascleral location ( p = 0.09) adversely affected OS, the latter association of borderline significance.

In addition, lesions of borderline significance may be up or down graded depending on the observer as shown in figure 5 .

The Hoorn study, conducted in an older Caucasian population, found that known diabetes was associated with PAD, while newly diagnosed diabetes was of borderline significance. 6 , 20 Unlike other studies, 5 , 6 we did not demonstrate an association between systolic BP and PAD or a protective association between HDL and PAD, but this might have been due to the sample size not being large enough.

In the adjusted analysis, both gender and ethnicity were of borderline significance while increasing age at time of infection was associated with a significantly greater risk of disease progression.

[ 29 ] reported higher serum IL-17A levels in patients with active AA, and IL-17A levels were also found to be varied among AA phenotypes, but the difference was of borderline significance.

When they examined more specifically a subset of 56 participants with early onset MDD and current depression, they did report some associations of borderline significance with Δ502–505 in women (4/8 neuropsychological features examined), and with a MDD family history in men.

There was no association between moderate PA and periosteal circumference (β = 0.015), a weak inverse association of borderline significance with endosteal circumference adjusted for periosteal circumference (β = −0.019), and a weak inverse association with BMD C (β = −0.025).

The decreased mRNA expression of Chmp3 and Fubp3 in mouse duodenum, presented a large effect size matching the direction of change observed in the orthologous human proteins, in spite of borderline significance.

When analyzed in quartiles, participants in the highest quartile (Q4) had 59% higher odds of stroke compared to those in the lowest quartile (Q1) (OR = 1.59, 95% CI: 0.98–2.57; P = 0.060), although this result was of borderline significance.

While there were some results of borderline significance, they were neither strong nor consistent across the different analyses.

Of borderline significance was increased sexual activity, measured as number of sexual partners in the last 6 months (OR [95%CI]: 1.82 [0.99, 3.32] increase per sexual partner).

Two-sided P values less than 5% were considered statistically significant and P values less than 10% were considered of borderline significance.

In the current study, BRCA1 methylation and survival association was of borderline significance ( P log-rank = .065).

A history of radiotherapy (P = 0.093) and WIC (P = 0.086) were of borderline significance in the univariate analysis.

Proportionally, more women who became pregnant consumed 14 units or less of alcohol a week compared with those who did not become pregnant (85% v 80%), and this difference was of borderline significance.

As a result, treatment effects that could not be detected or treatment effects of borderline significance in direct meta-analysis could be identified.

The positive association between PCB and SHBG levels among the Faroese young men is consistent with a previous study of Faroese 14-years old boys where increased SHBG levels were observed at higher PCB exposure levels [ 38 ] and, albeit only of borderline significance, in the Faroese fertile men [ 24 ].