“of borderline significance”

However, this is only of borderline significance due to a large TP53 mutant clone that spans 16 samples of donor SG1.

Our competing risk regression analysis also showed an association of borderline significance between high G-CSF responsiveness and non-relapse mortality.

Thus, the levels of IgG3 with specificity for MSP2 3D7, and of IgG1 with specificity for GLURP were both shown to be significantly higher in the AC versus UMA groups, while a similar trend, but of borderline significance, was found for IgG3 directed to the FC27 allele of MSP2.

Grade A erosive esophagitis with normal EAET was seen in additional 4/22 (18.1%) and was of borderline significance.

Our previous controlled evaluation of the intervention found statistically significant reductions in demand for CT scans and full blood counts, a reduction in demand for urea and electrolytes of borderline significance, and no change in demand for liver function tests [ 22 , 23 ].

The reactions directed toward unmethylated versions of Alu and LINE-1 sequences were of borderline significance when compared with global DNA methylation measurements ( Figure 5I and J ).

Contact with pandemic (H1N1) 2009–infected colleagues (aOR 2.5, 95% CI 0.9–6.6) and larger household size (aOR 1.2, 95% CI 1.0–1.4) were of borderline significance.

When all participants were included in the analysis as a total, we found that a 10 μg/m 3 increase in PM 10 was significantly associated at the nominal level with shortness of breath in the lag 1 whilst the association in the lags 2 and 0 to 6 was of borderline significance.

On the other hand, in receiver-operating characteristic (ROC) curve analysis, only target vessel was a significant predictor of the catheterization time but the area under the curve (AUC) value was only of borderline significance (AUC = 0.639, 95% CI: 0.501–0.762).

Presence of Candida -related, denture-related or tongue lesions was associated with a small increased hazard of total, non-fatal and fatal MI events, of borderline significance (Tables 2 – 4 ).

DBP decreased significantly in 9 of the 13 patients, 1 additional patient showing a small decrease of borderline significance, while the other 3 patients had no significant change in DBP.

The partial rescue by wnd 3 /Df mutations in hiw ΔN mutants is only of borderline significance (it was more significant when we used higher calcium bathing solution in our first submission).

Although AKT was of borderline significance, mTOR demonstrated no significant changes (Fig 3 A).

All factors that were of significance or of borderline significance on univariate analysis were considered for multivariate analysis.

Impact of sCAMS and Clinicopathological Characteristics on Overall Survival The univariable analysis showed that occurrence of liver and multiple organ metastasis was associated with a greater risk of progression, brain metastasis, higher grading, and sVCAM-1 levels above-median were of borderline significance.

Two variants, rs1805087 in methionine synthase, MTR and rs58225473 in voltage-dependent calcium channel protein encoding gene, CACNB2 are of particular interest, since associations of borderline significance were found in replication cohort and remain significant in combined discovery and replication groups (OR = 1.5, 95% CI, 1–2.3; p = 0.04 and; OR = 3.7, 95% CI, 1.25–11; p = 0.01, respectively).

Recently, the PanCancer TCGA consortium derived a DNA methylation and RNA expression stemness index, but their association with outcomes was of borderline significance [ 23 ].

The differences in serum uric acid and eGFR between the groups were of borderline significance ( Table 1 ).

4.7 Publication bias There was evidence of borderline significance for small study effect (p value 0.08, see Fig. 7 ). 5 Discussion Combining an iodinated contrast agent with FFDM (utilising a dual energy exposure undertaken during a single breast compression), CESM may improve diagnostic accuracy in the diagnosis and staging of primary breast cancer, particularly in women with dense breasts, due to its ability to identify breast cancer that might ordinarily be masked by the dense parenchymal background (DPB) patterns on a FFDM [ 13 , 19 , 20 , 27 , 41 , 42 ].

Work <50 h per week was associated with a higher scores, although this was of borderline significance.

However, using premenopausal non-cardia stomach cancer as the outcome, parity was associated with reduced OR of borderline significance (OR=0.82, 95% CI 0.65–1.03).

We also observed associations of borderline significance with the TIPARP rs2665390 polymorphism, which was previously found to be associated with ovarian and breast cancer, and with the EXOC1 rs13117307 polymorphism, which has been linked to cervical cancer in a large study in a Chinese population.

We also found exposure to SHS increased odds of e-cigarette use among traditional school students, but this correlation was of borderline significance among vocational school students.

This relationship was of borderline significance in multivariable analysis.

In addition, very recent meta-analysis, paradoxically, showed a significant increase in the risk of myocardial infarction and an increase in cardiovascular death of borderline significance with rosiglitazone, a member of PPAR γ agonists that is widely used as antidiabetic agent [ 49 ].