Accordingly, both nuclear and cytoplasmic HJURP immunopositivity were correlated with worse DFS (log-rank test, p = 0.071 for nuclear, p = 0.019 for cytoplasmic Figure 5 ), the former association being of borderline significance.
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“of borderline significance”
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In a follow-up study of the preterm infants randomised to breast milk or pre-term formula, differences in total cholesterol between the groups at age 13–16 years were of borderline significance [ 65 ], but there were differences in other lipoproteins, including a lower ratio of LDL to HDL cholesterol in the breast milk group. 3.5.2.
In men, risk of falls was greater only in those who reported poor eyesight and tended to be greater in those who reported poor hearing, although this latter association was of borderline significance.
Moreover, the correlation between the overall change in BIVA hydration and the corresponding directional change in fluid balance was weak and of borderline significance.
The means of the other markers (hsCRP, sIL-6R, IL-18, ICAM-1, and OPG) were not significantly different or of borderline significance in both groups.
The other cellular factors (ERBB- I and cyclin A) were only of borderline significance.
In the DCCT/EDIC, cIMT predicted decline in psychomotor speed over 18 years, but this association was of borderline significance after strict correction for multiple comparisons [ 5 ].
Participants who reported having a primary partner were more likely to indicate an intention to test by CHTC compared with those not in a primary partnership (40.4%), although this was of borderline significance ( Table 5 ).
An association between the accommodative and vergence responses in both tasks was weak and of borderline significance.
Of the trace elements, Zn concentration was lower in smokers (of borderline significance).
As the RLS relationship to the pain/anxiety dimension of the EQ-5D questionnaire was of borderline significance, this association was also checked in the multivariate design.
Overall, statin use showed a statistically significant risk reduction for all-cause mortality and CVD death, with RRs (95% CIs) 0.90 (0.86–0.94) and 0.86 (0.80–0.92), respectively, whereas the findings for omega-3 supplementation were of borderline significance, with RRs (95% CIs) of 0.97 (0.94–1.01) and 0.92 (0.87–0.98), respectively.
In the domain of general health and vitality, the results were of borderline significance, confirming a trend toward higher quality of life in participants with better exercise tolerance ( Table 4 ).
However, there were reductions in prevalence in many of the northern states between 2015 and 2018, and significant declines were seen overall in the North Central zone (PR adj =0.56, 95% CI 0.48 to 0.56) and North-West zone (PR adj =0.90, 95% CI 0.83 to 0.98), while the decline was of borderline significance in the North East (PR adj =0.85, 95% CI 0.72 to 1.00).
Multivariate analysis included proteins found to be significant (ER, PTHrPR1, OPN cyt ) or of borderline significance (CaSR and CK5/6) in univariate analysis.
Cox regression analysis showed that Ki-67 was of borderline significance as an independent predictor for DFS.
Notably, we found a direct association of MD adherence with apoA-1 concentration, but this was of borderline significance after Bonferroni correction for multiple comparisons, though it could be of potential clinical significance.
We found a linear trend of borderline significance between smoking status and polyp recurrence, consistent with previous reports focusing on the subsequent development of adenomas [24] , or hyperplastic polyps [25] .
The association for living in a household that owned livestock (versus living in a household that did not own livestock) was of borderline significance (odds ratio: 1.3; 95% CI: 1.0-1.7).
However, they remained except for moderate smokers who were inactive, the association attenuated and was of borderline significance only (HR=1.67 95% CI 0.99 to 2.81).
The excess risk of paraesthesia was only of borderline significance (95% confidence interval 1.00 to 1.23) and absent in patients undergoing vaccination in the late phase.
4 For the 576 patients treated after than 4.5 hours after onset the analysis failed to show a significant benefit of thrombolytic therapy, despite a non-significant trend towards a better outcome (number needed to treat 21.7, 95% confidence interval for odds ratio 0.9 to 1.6) and an increase in mortality of borderline significance, whereas the third international stroke trial (IST-3) suggested some clinical efficacy up to six hours, also associated with a signal of increased mortality. 5 A subsequent pooled analysis of the previous trials with the individual patient dataset from the third international stroke trial (IST-3) (
Although our results are only of borderline significance, we recommend that the variants reported here should be studied in additional datasets.
P-values <0.05 were considered significant and p-values of 0.05-0.10 were considered of borderline significance.
Adults with disabilities were more likely than peers without disabilities to be divorced/separated, although this difference was only of borderline significance (OR 2.0, 95% CI 1.0–4.2).