Similarly, in Blichert-Toft's study of mastectomy versus breast-conserving surgery for breast cancer [ 30 ], randomized patients were more likely than nonrandomized patients to experience the outcome of cancer recurrence (13.7% versus 6.6%), although the difference was of borderline significance (relative risk: 2.08; 95% CI: 1.07, 4.02).
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“of borderline significance”
In the literature
This is in agreement with our findings, which should be confirmed in further studies because the association between smoking and LBP was of borderline significance and only evident after adjusting for confounders.
To explore the prognostic potential of the proteomic targets, we used classification and regression trees (CART) to identify patterns of proteins that would robustly classify STS from LTS using the significant proteomic targets; for classification, we used the 7 significantly differentially expressed proteomic targets, as well as YWHAQ, which was of borderline significance.
Meanwhile, genetic associations with a 5 × 10 −8 < p -value < 0.05 were defined as being of borderline significance in GWAS or meta-analyses of GWAS.
Overall, socio-demographic characteristics were similar between the operator subset and the rest of the consented cohort who used mobile phones, apart from a slight difference in the ethnicity mix of borderline significance.
Although difference remained of borderline significance because of limited sample size, a greater incidence of late/very late ST was documented in the DES group as compared to the BMS group at bifurcation sites (main vessel: 75% versus 36%, P = 0.06; side branch: 42% versus 14%, P = 0.19).
However, TA was not cancer-associated and, although the difference between the mean TA values of benign and malignant cyst fluids was of borderline significance, some benign cyst fluids from cystadenomas showed high TA values.
Thus, treatment with liraglutide caused the greatest decrease of MDA, PCs and NT-proBNP (p < 0.05), while these changes were of borderline significance after metformin (Table 3 ) after adjusting for HbA1c, weight, BMI and waist circumference.
Even though this association was of only of borderline significance the result is in accordance with what has been seen in other studies [ 15 , 16 , 35 ].
To that end, when we normalized the virtual lesion data to a cohort‐specific template (ANTs_cohort), we found higher normalization accuracy compared to ANTs_mni that was of borderline significance (ANTs_cohort vs.
Differences between neonates and 1–3 year olds and between neonates and 5–12 year olds are of borderline significance.
All testing of significance was two-tailed and p-values were reported as significant if <0.05, and of borderline significance if 0.05–0.10.
Pretransplant CNTF serum level was also included in the following multivariate analysis because it showed a p -value of borderline significance ( p -value 0.08).
Finally, we observed a trend toward a greater increase in the rate of patients with BP or LDL-c controlled at the end of the study and a larger decrease of borderline significance in the SCORE and PCE predicted 10-year CV risk in patients on the polypill approach compared with patients who continued with the multipill strategy.
The prediction of 6MWD in absolute value ( Table 4 ) retained age, FEV1% pred, mMRC and baseline SpO2, with obesity, hypertension and diabetes as additional factors of borderline significance.
The impact of the FVL mutation appears to differ in regard to urine albumin excretion and plasma creatinine concentrations, considering that the difference in plasma creatinine concentrations was only of borderline significance or showed a trend between FVL-negative and FVL-positive individuals, while urine albumin excretion differed significantly in these two studies.
Among the hypoxia related markers, increased expression of HIF-1α (p = 0.061), TNF-α (0.059) and Apaf-1 (0.095) tended to be associated with reduced survival, although of borderline significance.
High elastosis was also associated with longer disease specific survival, although of borderline significance (98% and 96%, respectively, Figure 3 B).
However, this difference was significant in only 3 studies and was of borderline significance in 3 of 14 studies where GRS was measured.
In the adjusted analysis, these risks were slightly attenuated, and the risk related to snuff use was of borderline significance.
In our material the CHEK2 1100delC carriers were markedly younger at diagnosis compared to non-carriers, even though the difference was of borderline significance in the two groups of breast cancer cases and the material small.
( 15 , 16 ), in contrast, reported positive associations of borderline significance between IGF-I and risk of diabetes ( 10 ).
For this reason, our finding of borderline significance for children with obesity having higher rates of admission between 5 and 9.99 years must also be interpreted with caution.
However, in this review the authors included only 10 observational studies and concluded that no statistically significant differences were found in mortality, which might be explained by a smaller sample size compared to our study, especially given that their confidence interval was of borderline significance, and that they did not include some studies that would have met inclusion criteria as per their description [ 72 ].
Although of borderline significance, LTE 4 concentrations remained elevated in T2-high versus T2-low participants, having excluded those on montelukast (LTRA).