The study is underpowered to consider possible difference between groups of borderline significance (see mineralocorticoids receptor antagonists).
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“of borderline significance”
In the literature
A standalone study, in 2024, undertook an investigation into the asymmetry associated with the acetabulum using acetabular articular cartilage surface areas for the assessment of acetabular fractures, and reported a difference of borderline significance [ 32 ].
A significant negative association was found in relation to urban living (OR 0.48; 95% CI 0.32-0.73, p = 0.001), whereas the association with education level was only of borderline significance (p for trend = 0.051 OR 0.71; 95% CI 0.51-1.00) (Tables 2 and 3 ).
Such an observation was also of borderline significance in the univariable analysis in a study by Nastoupil and colleagues considering patients treated with axi-cel [ 15 ].
Immunomodulatory molecule loci-smoking interaction Interaction of IL1B (rs1143627) and former smoking on UC risk was of borderline significance ( P interaction =.05). 39 The increased UC risk for former smoking was only seen in those with CT/CC genotype compared with never smokers with TT genotype. 39 No interaction was seen for CD. 39 In addition, 4 polymorphisms in IL10 (rs1800872, rs1800871, 1800896, and rs3024505) did not demonstrate s
The use of dihydroartemisinin-piperaquine for IPT of malaria in schoolchildren was associated with reductions in parasite prevalence and annual entomological inoculation rate, but these were of borderline significance.
These potential explana- tions for our observation with regard to breakfast are speculative; this issue requires further investigations. Although the increasing trend in risk with quantity of tea consumed is of borderline significance only, the risks are substan- tial (over 3-fold at the highest level of consumption), and there is an almost 3-fold greater risk in those who drink beverages `very or burning' hot compared to warm.
The corresponding 1-year risk for MI was of borderline significance at 1.38 (95% CI: 1.00-1.77) .
Relaxing criteria to include common variants the strongest association was provided by the SNP rs7188880 (hg19 chr16:g.74664810.A>T, risk allele A, MAF =0.46, OR =1.41, P =2.15×10 −6 ), a synonymous SNP mapping to the gene encoding RFWD3 , which was of borderline significance. rs7188880 is in strong linkage disequilibrium with the missense variant rs7193541 ( r 2 =0.65, D’ =0.96) previously shown by GWAS to influence MM risk [ 6 ].
However, the association between the current use of atypical antipsychotics (AAP) and the mortality was of borderline significance, and there was no significant difference for past users of AP.
Reductions in FGF23 correlated strongly with reductions in calcium and phosphate, but not with PTH; correlations with bone turnover markers were inconsistent and of borderline significance.
[ 66 ] observed that the treatment group had a reduction in serum CRP of borderline significance compared to the placebo group.
In statistical models adjusting for age and decline in CD4 count (-100 cells), HIV-positive women had an increased OR for SCC (OR 1.6, 95% CI: 1.0-2.6) of borderline significance.
Those who performed rotating shift work (with and without nights) had a small increase in risk for SGA compared to daytime workers that was of borderline significance (OR 1.09, 95% CI 1.00–1.18).
Preterm children with CAs had a reduced risk of > 1 insulin/insulin analogue prescription compared with children with CAs born at term, which was of borderline significance.
The change in SGRQ score was also of borderline significance in these patients.
26 – 28 We observed a slightly higher azithromycin resistance prevalence in E coli isolates from children randomly assigned to the azithromycin group at 3 months but this difference of borderline significance was no longer present at 6 months, consistent with transient increases observed in some mass drug administration trials. 4 – 7 , 29 Our study had high retention (>99%), a well characterised study population, complete adherence to the first dose of study medication, and high adherence to the full 5-day course reported by caregivers.
Accuracy was related, in multivariate analysis, to palliative care team and (of borderline significance) patient age.
To guard against overinterpretation of hypothesis tests due to multiple testing, we recommend that P -values between 0.025 and 0.05 are considered of borderline significance.
Only HIV-1 infection and HR-HPV types were statistically significantly associated with HSIL in univariate analysis ( Table 3 ), while low CD4 cell count (<200 cells μ l −1 ) had an association of borderline significance.
When Chinese language trials were excluded in a sensitivity analysis, the magnitude of effect associated with neoadjuvant CT became of borderline significance.
Independent calculations for mild cognitive impairment and Alzheimer’s disease, with consequential loss of statistical power, showed similar odds ratios, significant for mild cognitive impairment and of borderline significance for Alzheimer’s disease.
In men, no variable was significantly associated with ukMI although the odds ratio (OR) for hypercholesterolemia was of borderline significance, 3.2 (95% confidence interval (CI) 0.9 to 11).
In multivariate analysis, the relationship between NT-proBNP and LAVI remains significant, while the relationship between NT-proBNP and LV EF is of borderline significance.
HRs were statistically significantly elevated for dockworkers and combination workers and were elevated but of borderline significance for LH and P&D drivers.