“not quite statistically significant”

One really crucial paper can cement an entire research career, and the temptation to favorably alter results that are not quite statistically significant may be too great.

Correspondingly, while not quite statistically significant, BMS treatment mitigated the increase of aspartate upon rotenone co-treatment in PC KO cells, with the partial effect in PC AB cells mirroring that of wild type cells in Figure 4D.

The estimated effect was however small (just over one-tenth of a point on a 0–10 scale) and not quite statistically significant.

64 ± 26%), these were not quite statistically significant.

There was a trend toward variation (p = 0.055), although it was not quite statistically significant at alpha = 0.05.

On the contrary, Lee et al recently analyzed EZH2 IHC expression in a cohort of DLBCL patients of similar size and showed that high EZH2 expression was associated with superior OS, with EZH2-high ABC patients being the subgroup with the highest OS, although this finding was not quite statistically significant in multivariate analysis [ 25 ].

Doxycycline resulted in a decrease in human tau in the detergent insoluble fractions without changing murine endogenous tau in pro-aggregant mice although the decrease was not quite statistically significant (Fig. 3a ).

The combination of selection bias and small sample sizes likely explains the counterintuitive (though not quite statistically significant) apparent decline in hazard for GS beyond 20%; our findings should not be interpreted as suggesting outcomes actually improve with higher GS, but merely that the strong effect observed among lower GS values seems to attenuate quite sharply above approximately 10%.

Additionally, although not quite statistically significant, mean NFT tau pathology score was 0.09 units lower for individuals with PSP and mtDNA haplogroup T, T1, and T2 backgrounds (N = 85) compared to other individuals (P = 0.009, Additional file 1 : Figure S1B).

While usually given at six and 10 weeks, doses at two weeks and four months (as in Bolivia), led to a measurable (though not quite statistically significant) improvement in vaccine effectiveness [27] .

Several authors have used this interpretation [ 34 - 36 ], understanding that some flexibility is desirable in interpreting p values, and that calling any value with p > 0.05 “not significant” is not recommended, as it may obscure results that are not quite statistically significant but do suggest a real effect [ 37 , 38 ].

Interestingly, though the decrease in risk of infection with CPZ (a first-generation antipsychotic) was not quite statistically significant, none of the 47 COVID-19 infected patients taking CPZ died of COVID-19 related causes.

In addition, the During COVID-19 cohort scored on average 1.707 points lower than the Before COVID-19 group on handwriting fluency, which was not quite statistically significant at the 5% level.

Additionally, people who are black appear to have a small increased risk of both hospitalisation and death, although the results are not quite statistically significant.

ERK1 is also reduced in the CaV-1 knock down samples, but the difference is not quite statistically significant.

21 and, while not quite statistically significant, they further support the advantage of using the endoscopic technique for transsphenoidal pituitary surgery.

Similarly, increased IFN‐γ responses in VL compared to NVL animals were observed in the BCG‐vaccinated animals when this parameter was determined at 4 to 12 months of the exposure period (Figure 3 b–f), although due to one outlying response, these differences were not or not quite statistically significant ( p values of 0.07 to 0.26, Figure 3 ).

3 A), but the difference between preparations with CIT below and above 5 h was modest and not quite statistically significant (Fig. 3 A, inset).

One caveat is that IL-4R expression is also significantly higher in HDAC3-deficient DP thymocytes (Figure 5A) and IL-4 leads to enhanced Stat5 activation (although this was not quite statistically significant).

Experiment 2 Figure 2 D shows that on average, the stimulus processing trade-off was as large as in Experiment 1 , but it was not quite statistically significant because there was more variability across participants.

Similarly, the health effects of SO 2 in the current period are positively associated with both NPC incidence and its growth rate, but not quite statistically significant like NO 2 .

The average annual injury rate in Yorkhill was higher than that of Kingston though the difference was not quite statistically significant.

Although the rate for the liquid inoculated coupon sets was also estimated to be less than that of aerosol-inoculated sets for carpet and galvanized metal, this difference was not quite statistically significant.

Ad4 also seemed to have a moderate affect; however the oncolytic cytotoxicity of this virus was not quite statistically significant from the buffer group.

Hazard 4: Clinging to the idea that a P -value close to but not quite statistically significant (eg, .06) supports a “trend” toward statistical significance.