“nominally significant”

There was a nominally significant benefit for GAD-alum treatment compared with placebo in lowering the increase in the standard deviation of blood glucose readings during the study period ( P = 0.0420 at 6 months, and P = 0.0219 at 15 months; Suppl Fig 1 ( 24 )), but there was no significant difference between the treatment arms regarding the coefficient of variation (standard deviation divided by the mean) measure of glycemic variability (Suppl Fig 2 ( 24 )).

In our supplemental analysis ( n = 33; Table S2 ), we observed a nominally significant reduction in SL (from 1.6 to 0.8 min, P = 0.042), a non‐significant yet clinically meaningful decrease in and the decrease TIB (from 527.5 to 479.0 min, P = 0.201), and no change in TST from 418.0 to 415.7 min, P = 0.416).

8 ), cluster 3 showed a nominally significant enrichment for genes located in CeD loci ( p value = 0.042; Fig. 5 C), with around 18% of cluster 3 genes being located near a CeD locus.

However, rs2614095 (intronic variant within PNOC ) was nominally significant in the present study (p = 0.042) and showed the same direction of affect across studies (minor allele A being protective).

In addition, we found nominally significant or suggestive associations of rs1237999 (A allele) with lower levels of CSF Aβ42 (p = 0.042) as well as higher levels of tau (p = 0.030), ptau (p = 0.011), and the ptau/Aβ42 ratio (p = 0.045) in the non-demented population ( Figure 2A ).

Gene expression change in FKBP5 was nominally significant between those who experienced response compared with those who experienced primary non-response to anti-TNF [log 2-fold change = -0.3551, adjusted p -value = 0.042].

Replication results In 461 adolescents, GMV IC 1-SNP component association was nominally significant after controlling for medication and five genomic ancestry components (uncorrected p = 4.20 × 10 −2 , \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\eta _p^2$$\end{document} η p 2 = 0.17).

Here we aimed to investigate the impulsive behavior of a healthy population of European descent, and found a nominally significant association (p = 0.042) between rs1051312 and impulsivity which did not survive the Bonferroni correction for multiple testing (p<0.0125 for 4 SNPs).

Gene-based association analyses Gene-based tests revealed a nominally significant association ( P = 0.0421; Table 3 ) of SCARB1 variants with HDL-C levels (best SNP: rs141545424 [p.Gly501Gly], exon 12, MAF = 0.0007, P = 0.0016).

Individual immune components did not show significant linear correlations with RGR; on median-split stratification, high B7-H3-positive tumor cell density was associated with a nominally significant difference in RGR ( p = 0.0428, unadjusted).

cruzi infection susceptibility The allelic and genotypic frequencies of seronegative and seropositive individuals from the Colombian cohort were compared in Tables S3–1 The minor allele frequency (MAF), in rs8193036*C was higher in seronegative than in seropositive individuals, being nominally significant after the adjustment by sex and age [P = 0.043, odds ratio (OR) = 0.83, 95% confidence interval (CI) = 0.70–0.99].

Two variants of KCNQ1 (rs179785 and rs179784) had a nominally significant association ( P = 0.043 and 0.044; OR = 0.85 and 0.86, respectively), but did not pass the significance threshold for multiple hypothesis testing using the Bonferroni correction.

However, t-tests were only nominally significant for left-aligned ( t (50) = −2.07, p = 0.043) and non-significant for central trials performed with the right hand ( t (50) = −0.98, p = 0.331).

We observed nominally significant evidence for population structure effects only for diastolic blood pressure (for PC4, p = 0.043) and for the ECG-derived parameter PR interval (for PC2, p = 0.044).

The HbO showed nominally significant differences between the two hemispheres during the happy (t(5) = 0.699, p = 0.043) and neutral tasks (t(5) = 3.459, p = 0.018).

A nominally significant improvement in pacing for the purpose to increasing the activity level could be seen in individuals who had received outpatient psychotherapy ( Z = 2.019, p = 0.043).

Nominally significant interaction was also observed between rs16899974 and prevalent cardiomyopathy on AF (P = 0.043).

In a pooled meta-analysis, the CC genotype showed a nominally significant, hypothesis-generating signal with obesity risk ( p = 0.043).

In a reverse-direction MR analysis using AP as the exposure and UA levels as the outcome, the IVW method showed nominally significant inverse association (OR = 0.989, 95% CI: 0.978–1.000, P = .043; Table 2 ).

Only peptidase activator activity, represented in part by FBLN1 , was nominally significant (adjusted p = 0.043; Table S5 ).

However, in post hoc analyses, it was observed that among subjects with high baseline TG levels [≥1.69 mmol/L (150 mg/dL)] and low HDL-C levels [<1.03 mmol/L (40 mg/dL)] who exhibited the highest risk of coronary events, there was a nominally significant 53% reduction in events [HR 0.47, 95% confidence interval (CI) 0.23–0.98; P = 0.043]. 38 Of note, the benefits seen in JELIS were consistent in both the secondary and primary prevention cohorts enrolled.

Tissue enrichment analysis of these 3 genes using MAGMA revealed nominally significant enrichment in nerve tibial ( p = .043) and artery aorta ( p = .047) tissues among 53 specific tissue types ( Figure S9A ).

Comparison of aFTLD-U cases with and without chr15q14 risk haplotypes We observed a nominally significant difference in age at death ( P = 0.043; Fig. 7a ) between aFTLD-U cases carrying haplotype A or B and those without association to chr15q14, with a subset of those without the haplotype showing an earlier age at death.

Among the variants that were included on the exome array, there was one nominally significant association with A-kinase anchoring protein 9 ( AKAP9 ) rs149979685 ( β = −3.117 (SE = 1.538) number–symbol pairs; p = 0.043) in African-Americans after adjusting for age and gender that did not survive adjustment for multiple comparisons (Supplementary Tables 6 , 7 ).

While nominally significant uncorrected P values were observed in the left occipital white matter (P=0.043), left occipital gray matter (P=0.010), and left thalamus (P=0.046), these differences did not survive rigorous adjustment for multiple comparisons.