With respect to tumor burden growth rate, no effect of DFMO was found, but there was a nearly significant ( P = 0.07) effect of sulindac.
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No significant differences among the groups at any of the sample types and any of the study visits were observed, although a nearly significant p -value ( p = 0.07, F = 1.28) was obtained among the three groups of saliva samples, collected at V4 ( Supplementary Figure 2 ).
Articulation The post-hoc Bonferroni test showed nearly significant differences in articulation between correlation means for (R affective 1/2) and (R cognitive 1/R affective 1) at p = 0.07, but did not indicate significant differences either between (R cognitive 1/2) and (R cognitive 1/R affective 1) or between (R cognitive 1/2) and (R affective 1/2).
These differences were statistically significant in the aorta [median (IQR): 742 (322–1337) vs 365 (39–1144), p = 0.05], iliac arteries [median (IQR): 633 (242–1148) vs 337 (66–764), p = 0.02] and the total arterial calcification mass score [median (IQR): 1694 (812–3584) vs 1182 (235–2445), p = 0.03] and was nearly significant in the calcification mass score of the legs [median (IQR): 309 (93–851) vs 90 (11–627), p = 0.07].
The intervention factor had a nearly significant impact on F wave amplitude (F (2, 18) = 3.10, p = 0.07).
The main effect of run was significant for the left insula, F(3,138)=11.40, p<0.001, right insula F(3,138)=3.19, p<0.05 and visual association cortex, F(3,138)=15.43, p<0.001, and nearly significant in the left amygdala, F(3,138)=2.66, p=0.07.
The only exceptions were SNAC1 and PR1#74 , which showed significant or nearly significant impacts of time, treatment, and their interaction ( SNAC1 , ANOVA: time, P = 0.07, Cohen’s f = 0.471; treatment, P = 0.05, Cohen’s f = 0.76; time x treatment, P = 0.07, Cohen’s f = 0.72; PR1#74 , ANOVA: time × treatment, P = 0.07, Cohen’s f = 0.73).
However, tumor site and previous treatment with taxane were nearly significant (OR = 3.68; 95% CI: 0.90–15.03; P = 0.0700 and OR = 1.72; 95% CI: 0.93–3.21; P = 0.0863, respectively).
We removed non-significant effects in a stepwise procedure, arriving at final model that included nearly significant effects of SC trial type (F 1,30 = 3.5, P = 0.07) and SC allopatric male display rate (F 1, 30 = 2.9, P = 0.10) and a significant effect of SC sympatric male display rate (F 1, 30 = 5.4, P = 0.03).
In a regression model that adjusted for the three clinical variables found to differ with decreased post-operative attention score (i.e., lower BMI, cardiovascular disease, and increased age), a similar, nearly significant relationship was observed between crossover point and change in attention score (proportional odds ratio 1.25, 95% CI 0.99–1.59, p = 0.07).
control), together with a nearly significant TNF α increase ( p = 0.07 vs. control).
EUR 8523, p = 0.070, nearly significant), mostly driven by the expenses for other drugs (EUR 1059 vs.
At follow-up assessment, the time*group interaction effect on DBAS and SE remained significant: p = 0.02 and p = 0.0001 accordingly, while the same effect on WASO was only nearly significant: p = 0.07.
GLM performed on the continuous variable of impulsivity and the peak of response of amphetamine showed a nearly significant effect (F(1,34) = 6.07; p = 0.07 after adjusting p-values using FDR controlling procedures).
2 ), although a nearly significant increase was observed when comparing the highest MP concentration and controls (estimated difference: 0–50 = −845± 476, df = 141, t.ratio = −1.77, P = 0.07).
There was a nearly significant interaction effect between age group and reward magnitude [F(2, 68) = 2.71, p = .07] (see Figure 3A ).
MANOVA of PC1-PC9 for geminate species by range in Dormitator was highly significant ( p = 0.001), significant in Eleotris ( p = 0.015), and nearly significant for Gobiomorus ( p = 0.07).
Higher intake of the HGDiet pattern was associated with more amyloid accumulation in the lateral temporal lobe (β = 0.09, p < 0.05), posterior cingulate gyrus (β = 0.09, p < 0.05), and precuneus (β = 0.11, p = 0.01) with nearly significant increase in global amyloid (β = 0.08, p = 0.07).
The nearly significant difference in seroprevalence between roe deer of different ages ( p =0.07, highest in animals <1 year) is in agreement with Gerth et al. 1995 ( 64 ) who suggest most infections occur at an early age.
The pooled analysis showed that the sequential combined treatment was associated with a 36% reduction of the risk of relapse, a significantly better DFS (HR, 0.63; 95% confidence interval [CI], 0.41 to 0.99; p=0.04), cancer specific survival (HR, 0.55; 95% CI, 0.35 to 0.88; p=0.01) and a nearly significant improvement of OS (HR, 0.69; 95% CI, 0.46 to 1.03; p=0.07).
In model 1, for ghrelin levels, no significant association was noted with the five variables but association with HOMA-IR was nearly significant ( P = 0.070).
There was also a significant improvement of PFS (median: 2.1 months with regorafenib versus 1.1 months with placebo) (adjusted HR = 0.33; 95% CI: 0.15–0.74; p = 0.007) and a large and nearly significant OS benefit despite the cross-over (adjusted HR = 0.49; 95% CI: 0.23–1.06; p = 0.07; median OS = 17.8 versus 8.2 months) ( 47 ) ( Table 3 ).
The correlation between muscle strength and pain-related disorder scores on the JOABPEQ was nearly significant (r p = 0.40, P = 0.07; Table 7 ).
For PM 2.5 , there was a significant ( p = 0.03) decrease in RMSSD and a nearly significant ( p = 0.07) decrease in SDNN for the 0130- to 0430-hr interval but no such an association during the 1600- to 1800-hr period.
On the contrary, among 157 patients undergoing adjuvant chemotherapy (a heterogeneous group of node-positive and/or pT4 and/or radically resected liver metastases patients; i.e., high-risk stage II patients and stage ≥ III cancers), MSS patients showed significantly better DFS rates (HR = 0.37; 95% CI 0.14–0.89; p = 0.005) and nearly significant OS rates (HR = 0.51; 95% CI 0.20–1.29; p = 0.07) than MSI patients, thus demonstrating that MSI tumors in advanced stages, requiring adjuvant therapy, are significantly disadvantaged or even harmed with conventional chemotherapy schedules ( Figure 2 and Figure 3 ). 3.2.