When comparing the means between the KOOS pain quartiles, the difference in CGRP levels were nearly significant, with higher mean concentration in the high-pain group (low pain: 24.7 ± 16.2 pg/mL versus high pain: 40.7 ± 23.5 pg/mL; p = 0.0547) (Figure 2E ). 2-AG and AEA levels in SF LC-MS/MS analysis of endocannabinoids in SF revealed significantly higher levels of 2-AG in patients in the high-pain group (20.9 ± 10.3 ng/mL) compared to the low-pain group (14.9 ± 7.1 ng/mL) (p = 0.0358) (Figure 3A ).
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Similarly, we found a trending, nearly significant increase of both early apoptotic (P = 0.0549) and late apoptotic (P = 0.0547) DN T cells with QAC exposure ( Figure 6D ).
After 1 year, the slope for the high-dose arm was nearly significant larger ( P = 0.055) than the standard-dose arm.
While less precisely estimated, the OLS and FE results based on the MTFS twins display the same pattern; the nearly significant ( p = 0.055) OLS estimate becomes negative and insignificant in the fixed effects model.
Both alpha-diversity metrics were nearly significant for the experimental outcome (p-value = 0.055) of A. palmata , with visually unaffected and diseased corals showing higher diversity measurements compared to controls.
A main effect of task was also nearly significant ( F (2,220) = 2.94, p = 0.055, η 2 = 0.01), with a higher percentage of anticipatory saccades occurring in the Gap task (9.33 ± 1.06%) compared to both the Step (8.12 ± 1.14%) and Overlap tasks (5.91 ± 0.87%).
Notable metabolite class trends include a significantly higher concentration of total AAs ( P = 0.038) and a nearly significant elevation in bile acids ( P = 0.055) among RCs compared with those with recurrent NAFLD on histology.
Concomitantly, there was a nearly significant 30% reduction in the less abundant pre-ins1 message (p = 0.055) ( Figure 3B ).
Expression of the CXCR6 gene (Th1) was significantly enhanced (p<0.0001), while the increased expression of the CCR6 receptor (Th17) was nearly significant (p = 0.055) ( Fig 3B ).
A Mann–Whitney analysis revealed a significant difference between groups in relation to the abundance of Cutibacterium acnes ( p = 0.041) and a nearly significant difference with Adlercreutzia equolifaciens ( p = 0.055).
Hs-CRP is nearly significant but poorly co-related with a total length of the stent (r2 = 0.14, p = 0.055) but not (negatively) with a total number of the stent (r2 = -0.07, p = 0.5).
Post-hoc tests revealed significant decrease in pNN50 and pNN10%(meanRR) at 9, 12 and 24 months of age, and the decrease was nearly significant at 18 months of age ( p = 0.055), as well as at several timepoints from the age of 9 months for the HRV triangular index, signing decreased heart rate variability.
In SLG samples, Zn concentrations showed a nearly significant increase at 200–600 m compared to 0–200 m (8.99 vs. 7.38 mg·kg −1 f.m.; p = 0.055), while Cd levels were significantly lower at the greater distance (0.13 vs. 0.19 mg·kg −1 f.m.; p = 0.015).
In contrast there was only a nearly significant improvement in the subgroup of cardiologists (37.1% in 2000 to 46.6% in 2005, p = 0.055).
Furthermore, we observed a nearly significant correlation between LIFG activation in response to SIQ and speech performance ( r = 0.314, p = 0.055; Figure 5H ).
The model for HCPs‐rated pain showed a significant main effect for the contrast T1–T2 ( β = −1.40, t = 2.34, p = .020), intervention group ( β = −2.01, t = 2.56, p = .011), age ( β = −0.36, t = 5.11, p = <.001), and a nearly significant main effect for the contrast T1–T3 ( β = −1.36, t = 1.93, p = .055) and status of liver transplantation ( β = −0.60, t = 1.70, p = .091).
A nearly significant reduction in new or worsening nephropathy was also observed (RR reduction: 18%; 95% CI −1 to −32%; p = 0.055).
For lung symptoms, the effect was nearly significant (p = 0.055) for a lag of one day but with two or three days, there was none.
The observed decrease between T2 and T3 was nearly significant, with p = 0.055.
Although nearly significant ( p = 0.055), mRNA of CD8A (Cluster of Differentiation 8a), the cytotoxic T cell surface glycoprotein and GZMA (granzyme A), produced by CD8 T cells, were also upregulated 3.53- and 3.62-fold, respectively.
Diabetes showed a lower odds ratio (OR; nearly significant, P = .055) for PASS acquisition, and diabetes (OR, 0.348 [95% CI, 0.130-0.931]; P = .036) and large to massive tear (OR, 0.378 [95% CI, 0.162-0.884]; P = .025) were significantly negatively associated with SAAS acquisition.
The presence of CEA mRNA-positive CTCs in preoperative peripheral blood samples had nearly significant impact on DFS (HR =1.9; 95% CI: 0.99–3.5; P=0.055) and CSS (HR =2; 95% CI: 0.95–4.01; P=0.067).
For the 120 min period after the second treatment, two-way ANOVA finds a main effect of amphetamine treatment ( F (1,32) = 63.791; p < 0.001), a nearly significant effect of CNO treatment ( F (1,32) = 4.027; p = 0.055), and a significant CNO treatment × amphetamine treatment interaction ( F (1,32) = 6.489; p = 0.017).
Moreover, a nearly significant association is present as far as the age of smoking onset is concerned ( P = 0.055), that is, patients who started smoking later (C level) found harder to quit smoking than those who had started earlier (A and B levels).
Under an oxidant environment, all treatments were able to reduce 8-OHdG levels, although the reduction was only nearly significant in the NQ group ( p = 0.055, Figure 1 B). 2.2.