Notably, the P value for interaction was nearly significant ( P = .054) between subgroups of patients who had received previous hormonal therapy (HR, 0.45 [95% CI, 0.31 to 0.65]) and those who had not received previous hormonal therapy (HR, 0.79 [95% CI, 0.51 to 1.23]).
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On multivariable Cox regression, only procedure type (combined and transcranial approaches) remained significant prognosticators [HR:8.616, p = 0.004, and HR: 17.559, p = 0.017, respectively] with Kadish-Morita Stage D being nearly significant [HR:14.35, p = 0.054].
However, this difference was nearly significant for premature withdrawals due to cancer progression [2/27 (7.4%) vs 9/36 (25.0%); p = 0.054].
Additionally, the probability of being cluster U1 showed a nearly significant relationship with electrophysiological score ( P -value=0.054; adjusted R-squared= 0.055).
Pre-planned contrasts confirmed a significant difference between limnetic and benthic fish in Priest Lake ( t 9 = −2.43, P = 0.038) and a nearly significant difference between limnetic and benthic fish in Paxton Lake ( t 9 = −2.21, P = 0.054).
As can be expected following the results above, following the intervention in English significantly larger gains are observed in English ( M = 0.27) than in Hebrew ( M = 0.05) for target words that were taught in English, t (21) = 5.93, p < 0.001, and following the intervention in Hebrew larger gains are observed in Hebrew ( M = 0.11) than in English ( M = 0.02) for target words that were taught in Hebrew, and the difference was nearly significant, t (21) = 2.04, p = 0.054.
Nearly significant non – linear associations were found between CTQ total score and incidence of depressive episodes (df = 2.9, p =0.054) and (hypo) manic episodes (df = 7.4, p =0.085; see Additional file 1 : Figure S2).
Distance to main roads is significant in the rail ( p = 0.038) and nearly significant in the total sound model ( p = 0.054).
Stratified analysis highlighted nearly significant OS improvements with high-dose FSRT and targeted therapy ( P = 0.054), while concurrent therapy markedly enhanced iPFS ( P = 0.027).
Following 7 days of treatment in subjects with MDD, a 1 : 1 ratio of BUP and SAM, the ratio associated with maximal antagonism of opioid effects, exhibited statistically significant improvement vs placebo in HAM-D17 total score ( p =0.032) and nearly significant improvement in Montgomery-Åsberg Depression Rating Scale (MADRS) total score ( p =0.054).
Although the later sample was rather small, significant differences in relative head length and depth of caudal peduncle, as well as a nearly significant ( p = 0.054) difference in body depth, were revealed between GN sampled in 2009 and 2019 ( Fig 7 ).
Also, a trending significant reduction (P = 0.10) was observed only after 2 weeks when compared to the placebo group and was further confirmed to a nearly significant level (P = 0.054; F = 3.94) using the ANCOVA model.
Finally, bivariate two-way Pearson correlations showed that the magnitude of SAS provoked by the distressed avatar was associated (nearly significant) with the perspective-taking capacities of the participants under the observing ( r = 0.398, p = 0.054) but not the empathizing conditions.
group ( P < 0.001), while it was nearly significant in the non- Acinetobacter spp. group ( P = 0.054).
The difference in conjugation frequencies between different plasmids was nearly significant ( p = 0.054).
NAD showed a nearly significant difference, remaining better described as trend toward a difference (p = 0.054 (CI:0.050 to 0.058), 12000 randomizations).
The COVID-19 infection rate among overall population was 55.83%, with a nearly significant difference by gender, 33.25% for males and 66.75% for females ( P = 0.054).
In addition, nearly significant differences ( p = 0.054) existed between the pre-exercise untrained and postexercise untrained groups, suggesting a larger magnitude of changes in human exercise-related characteristics than in those leading active lifestyles.
Eyes with pseudophakic status after the surgery were significantly less likely to maintain ≥65% gas fill on POD3 ( P = 0.003), and the difference was nearly significant on POD4 ( P = 0.054).
Post hoc comparisons showed a significant increase in glutathione levels in the NAC 0.1 mM + OGD group compared to CTR and a nearly significant effect when the former was compared to OGD ( p = 0.0543).
Age was insignificant for HDL-C but was included because age-squared was nearly significant (p < 0.0543).
The humanized mice group that had been fed the GE diet had a nearly significant reduction in tumor volume (p = 0.0545) ( Fig 8A ).
For patients with baseline dyskinesia, improvements over placebo were also significant ( p = 0.0153) in patients with or without changes in levodopa dose, and nearly significant ( p = 0.0546) in patients with no change in levodopa dose, suggesting that these improvements were not due to levodopa dose reductions.
We also looked at how CA 125 is related to age and found a nearly significant pattern ( p = 0.0546): we observed a trend toward higher average and median CA 125 levels in patients ≤40 years ( p = 0.0546) ( Table 3 ).
When comparing the means between the KOOS pain quartiles, the difference in CGRP levels were nearly significant, with higher mean concentration in the high-pain group (low pain: 24.7 ± 16.2 pg/mL versus high pain: 40.7 ± 23.5 pg/mL; p = 0.0547) (Figure 2E ). 2-AG and AEA levels in SF LC-MS/MS analysis of endocannabinoids in SF revealed significantly higher levels of 2-AG in patients in the high-pain group (20.9 ± 10.3 ng/mL) compared to the low-pain group (14.9 ± 7.1 ng/mL) (p = 0.0358) (Figure 3A ).