Among patients subjected to aortic valve and/or aortic surgery, regression analysis showed significant association of fever, C-reactive protein (CRP) elevation between 5 and 100 mg/L, urgent procedure and postoperative antibiotic use with PPS diagnosis, whereas younger age showed near-significant association.
Living Moso bamboo and living stems of other species displayed significant or near-significant positive correlations at 0–6 m scales, but these associations became non-significant beyond 6 m ( Figure 4 e).
Both IL-6 and IL-8 showed significant or near-significant increases by ELISA in simulated microgravity, while IL-1β demonstrated a trending increase (Fig. 6G , Supplementary Fig. 19E ).
Variables were selected for inclusion in the multivariable model based on clinical relevance, prior evidence, and significant or near-significant associations in univariable analysis.
To start with, we found a near-significant result together with a moderate effect size regarding age differences in gaming debut, indicating that the study could have been underpowered in this aspect.
Prediction of Dementia and Decline Univariate logistic regression analysis revealed a significant association between low Aβ 42 at baseline and conversion to dementia as well as near-significant associations both between memory decline in the first 2 years of follow-up as well as slightly below normal executive T score at baseline, and development of dementia (Table 5 ).
Following strict multiple comparisons correction, these findings were attenuated to strong, near-significant nominal trends ( p BH = 0.067 and p BH = 0.060, respectively).
The main effect of Signed- Δ -Magnitude on Dominance was only near-significant due to the Šidàk correction.
Significant or near-significant differences were observed in specific domains and time points as follows.
However, it may make some of the near-significant associations non-significant to improve the reliability of the results.
Among these, LAScd ( p = 0.019) and SBP ( p = 0.083) remained significant or near-significant after correction, confirming limited overfitting and good internal consistency of the final model ( Supplementary Materials Table S1 ).
We found that mRNA expression of monocyte chemoattractant protein-1 (MCP-1) and toll-like receptor-4 (TLR-4) were significantly increased in FR1 mice compared with control mice, and the mRNA expression of interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) showed a near-significant increase compared with the control.
Glucose treatment resulted in a near-significant increase in OPC proliferation (SOX10+/PDGFRα+/BrdU+; Fig. 1D ).
The near-significant difference in capsule completion, together with the highly significant transit-time prolongation, supports the need for a larger prospective study powered for completion rate and the need for repeat examination as clinically meaningful endpoints.
Variables demonstrating theoretical relevance and significant or near-significant bivariate associations were entered into the model.
For instance, Higashikawa and colleagues [ 42 ] assessed the anti-obesity effect of Pediococcus pentosaceus LP28 among 62 overweight individuals in a randomized, double-blind, placebo-controlled fashion and noted that the probiotic group experienced a near-significant mean difference from placebo for BMI (mean, [95CIs]; -0.33 kg/m 2 [-0.74, 0.08]) following a 12-week intervention.
7 ), and found a near-significant increase in cAMP response to 100 nM GIP compared with GLP-1 stimulation in wild-type INS-1 832/3 cells ( Fig. 7A ), a tendency replicated in primary mouse islet beta cells ( Fig. 7B ).
Engagement in this activity has shown a fall in blood pressure, with a substantial fall in MAP of 4.04 mmHg, a significant fall in DBP of 3.93 mmHg, and a near-significant fall in SBP of 4.27 mmHg.
Additionally, the near-significant p-value of 0.09 for U-Net + Inception V3 versus U-Net + VGG16 indicates a slight but not statistically significant difference in performance, suggesting their potential equivalence in effectiveness.
The distance from the glacial refugium had the strongest effect on pollinator-perceived petal color, but there was also a modest and near-significant influence of small bee visitation rate.
In contrast, risk behaviors that place participants in exposure to potentially contaminated environment near the household, such as contact with mud, sewage water, or garbage, and cleaning an open sewer, had a significant or near-significant association with both primary and secondary infections.
A lower expression of the MLH1 gene, which is also located on chromosome 3p, was significantly related to prognosis in one cohort and showed a near-significant effect in the other cohorts.
In males, all traits except bill width differed significantly across study sites after Bonferroni adjustment ( Table 2 ); in females, only bill depth differed significantly across study sites, but bill-head length, bill-nostril length, and bill width showed near-significant variation ( Table 2 ).
However, for beta diversity, near-significant differences were observed between the post-operative SG and GB populations at both the family and genus levels of taxonomy.
Conclusions : Across 401 real-world procedures in isolated popliteal and/or SFA disease, mean ABI gain was identical between arms, yet DCB delivered measurably more complete symptomatic recovery and a near-significant halving of composite patency loss at 12 months, with both signals robust to multivariable adjustment.