Barely Significant
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“near-significant”

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Listed by Otte et al. (2022)

In the literature

15.4 [1.5]; p = 0.020) ( Figure 3D ), and near-significant elevations in percentages of both CD8 + T cells and naïve CD4 + T cells. 4 Discussion The COVID-19 pandemic is reminiscent of the dilemma in our daily practice, which is to maintain adequate immunosuppression for controlling autoimmune diseases while risking a higher probability of non-responsiveness to vaccination ( 12 , 13 ).
Finally, the near-significant stepwise increase in severe IVH (6.8% → 19.4% → 33.3%) highlights a pattern that has been linked in other cohorts to infection-related hemodynamic instability and inflammatory injury, and multiple studies report worse neurodevelopment after neonatal sepsis in extremely preterm populations at 2 years of age [ 22 , 23 ].
However, factors such as body mass index, smoking, hypertension and diabetes did not significantly influence CKD risk, although cardiovascular disease showed a near-significant association. 6 Although there is some controversy regarding the extent of CKD risk associated with lithium versus other treatments, 7 older people appear to be at a higher risk.
( 54 ) demonstrated that amygdala-hippocampal RSFC is increased acutely in MDMA administration compared to placebo and this increase occurred in a manner that correlated with the drug’s subjective effects at a near-significant level, leading these researchers to propose that this functional connection was a primary target of MDMA-AT.
As for the analysis predicting depressive symptoms in this diagnostic group, neither the total indirect effect of the three cognitive variables nor the specific indirect effect of any of them reached statistical significance, although the specific indirect effect of neuroticism on depressive symptoms through brooding was near-significant.