“near-significant”

Although their beta weights from the regression analyses were not as large as .31, they output near-significant coefficients of .22 and .21, which were still greater than the other nonsignificant measures.

However, a fourth molecular study on shorebirds [ 30 ] based on both mitochondrial rRNA and three different nuclear loci (beta-fibrinogen intron 7, GAPDH intron 3-5, and ADH intron 5) yielded a third possible topology, a grouping of terns and skimmers, which had full support for MP analyses and near-significant support from ML analyses (87%).

Using the same logistic mixed effects models from Study 1, we obtained the following relevant significant or near-significant 10 main and interaction effects: (1) Language; (2) Canonicity; and (3) Language × Canonicity.

Significant or near-significant enrichment for genes regulated by Myc, DNA repair, mTORC1 signaling, PI3K–Akt–mTOR signaling and protein secretion in all three gene sets was found (Fig. 6b ), identifying these pathways as potential regulators of 5′-C transcript metabolism.

However, that was not the case here providing further support that the near-significant trends seen in this study likely reflect real negative effects of these nonstandard diets on body size, weight, and fat composition.

The marginal p -value of 0.062 suggests a near-significant upward trend with cumulative usage.

Boxplots for the comparisons of the abundances for taxa with near-significant p values (e.g., 0.063–0.059) are available in Figure S3 .

Both SNPs rs7161 and rs4660761 ( DPH2 and ATP6V0B ) were highly significant in a mega-analysis in a combined cohort of 180 self-reported European-Americans; SNP rs1800934 ( MSH6 ) was near-significant in a meta-analysis assuming dominant effect of the minor allele.

Additionally, we performed a multivariate logistic regression analysis; the results indicated that while there was no significant effect of sex on the BA profiles, age may have an influence, as suggested by a near-significant difference(Table S4 ).

The near-significant difference in telomere length between older and younger PCS patients suggests that PCS may accelerate age-related telomere shortening.

A p value below α corrected was considered as statistically significant, while a value between α corrected and the standard 0.05 threshold was only regarded as near-significant (but potentially biologically relevant).

There are indications that the probiotic supported such a transition, with CST 1 showing a near-significant association with the probiotic group.

For all EGG parameter analyses, there were significant or near-significant effects of BMI as a covariate (see Table 3 ).

Similarly, ordinal logistic regression demonstrated higher levels of ADA were associated with a near-significant increase of odds of a more severe stroke based on NIHSS at discharge (p ​= ​0.053).

In line with these findings, a near-significant decrease in lymphatic drainage was observed in the ear skin of IL-7Rα ΔEC mice (Fig. 5c,d ).

While both genders considered similar criteria when evaluating others’ smiles, females paid more attention to general dental appearance, with a near-significant tendency towards being more attentive to tooth cleanliness.

We found no significant differences in expressions of the hypertension-associated genes between the pre-HCT and post HCT groups, with only a few genes showing near-significant differences and no consistent pattern (including NR3C2 gene with higher expression in the pre-HCT group and PIK3CG with higher expression in the post-HCT group, both differences non-significant).

Pyroglutamic acid and urea had a significantly lower quantity in the BPD group compared to No BPD (0.031, 0.0031 respectively), with a near-significant difference when compared to the Term group (0.087, 0.062 respectively).

There was also a near-significant association of psychological distress measured with the GHQ and pro-inflammatory IL-6 responses.

In the present study, the transcutaneous delivery of stimulation, applied at motor threshold in a purely sensory nerve injury, may not have provided the selectivity or intensity of fiber activation necessary to trigger these mechanisms. 41 Although age showed a near-significant effect in some models, its overall influence appears limited.

Additionally, GH, with a near-significant P -value of 0.052, was also considered in the LASSO regression to ensure a comprehensive variable selection.

However, the near-significant results warrant attention, particularly for policy and practice development.

A significant temporal variation in Shannon diversity was observed at both beaver and non-beaver sites, while a near-significant temporal variation in Simpson’s diversity was observed exclusively at beaver sites ( Figures S5 and S6).

Similarly, patients with cholesterol ≥ 200 mg/L had elevated hs-CRP levels in PDR (11.24 ± 17.28 mg/L), while those with cholesterol < 200 mg/L showed lower values (4.48 ± 3.63 mg/L), with a near-significant p-value of 0.060 ( Table 3 ).

The near-significant association with anti-HBc antibody positivity is particularly noteworthy, as it hints at a possible interaction between prior viral hepatitis exposure and the progression of liver disease in SCD.