The near-significant negative correlation between MMP-9 and proteinuria at T3 further supports the notion that fibrotic processes, rather than inflammation, become the dominant force driving kidney injury and proteinuria over time.
Nevertheless, we demonstrate that OSM, TGF-β1, and Snail drive a significant change to the Epithelial-Mesenchymal Transition Hallmark gene signature from the Molecular Signatures database, with Zeb1 driving a near-significant alteration (Supplementary Fig. 7 A–D).
Collectively, these results suggest that the clinical benefits of PCDF are robust and largely unaffected by the use of postoperative cervical collars. An additional observation was a near-significant imbalance in the number of patients undergoing five-level fusion, with more cases in the no-collar group (eight patients) compared with the collar group (two patients; p = 0.051).
Thus, the association between duration of music training and IQ was near-significant when demographic variables were held constant, although it was weaker than in previous correlational studies with older children (Schellenberg, 2006 , 2011a ; Corrigall et al., 2013 ) and in a quasi-experiment with same-age children (Schellenberg and Mankarious, 2012 ).
A near-significant correlation was found between reward-based cognitive inflexibility and OCD-symptoms.
Additionally, CDK4 and CDK6 showed a near-significant association (p value: 0.06).
Similarly, SWLM significantly differed from obese participants or exhibited near-significant trends in all regions, with the exception of the left middle insula and left temporal gyrus.
Contrary to expectations, aphid colonization was unaffected by eT or eCO 2 , but there was a near-significant 10% reduction in colonization rates on plants with weevils present belowground.
No significant or near-significant findings emerged among participants with HDRS scores <7.
Opinions of the healthcare workers on treatability of childhood autism showed near-significant association with geographical region, with the healthcare workers located in the south-east region of Nigeria more likely to express the opinion that childhood autism is treatable compared to those located in the south-south region of the country (chi square = 3.32, df = 1, p value = 0.068).
This result is in line with the review by Corrini et al, 25 which reported a significant association between effect and session time and a near-significant association with total training volume.
The near-significant p -value of 0.06 and the weak correlation (r = 0.143) suggests that with a larger sample size or more refined study design, this association might become clearer.
Since LH shows pulsatile secretion during the day (e.g., [ 15 ]), a half-day urine sample was collected in a subset of participants, to be analysed in the event of near-significant results on serum LH.
Improvements in the VO 2 peak were accompanied by greater muscle citrate synthase (+46%) and a near-significant increase in creatine kinase (+15%) activity in TG.
One study ( 42 ) reported a near-significant effect at 6 months regarding the Drug Score (OR = 0.7; 95% CI = 0.5–1.0), which disappeared at 9 months.
Specificity of Cross-Sectional Correlation Most of the clinical scores analyzed (12 of 15) showed significant or near-significant negative correlation with delta-band EEG power.
FEV 1 (forced expiratory volume in 1 s): There was a near-significant main effect of time on FEV 1 values, indicating a trend toward overall improvement across the sample.
When each tooth was considered as the measurement region, a near-significant difference in the error of the superimposed areas was observed between groups ( Table 2 ).
For lateral electrodes, when there was a significant or near-significant three-way interaction of the spatial factors Hemisphere and Anteriority with the Condition factor, repeated measures ANOVAs for each Region were conducted separately, with post hoc comparisons between the Aspect mismatch condition and each of the two other conditions (Bonferroni corrections were applied).
In this analysis, near-significant mediation effects were observed for connectivity between CA1 and the individual retrosplenial parcels (bilateral Rsp1 and Rsp2), approaching significance ( p ( a × b ) < 0.05, Table S10 ).
This near-significant pattern is consistent with the expected biomechanics of raised intracranial pressure: the ONS serves as a distensible CSF-filled compartment and therefore expands early in the course of ICP elevation.
Overall, none of the clinical variables were significantly associated with early recurrence, except for microvascular invasion, which demonstrated a near-significant association.
Although we did not have sufficient numbers of patients with post-treatment samples to attempt to analyze sex-related differences, we did observe, as previously reported in lung cancer patients ( 16 ), a significant increase in CXCL10 in non-responders while on-treatment, as well as a near-significant increase in IL-6.
In addition, there was a near-significant association within ZMAT4 (zinc finger matrin-type protein 4) in participants of African ancestry.
Wilcoxon tests revealed significant differences in DNA methylation levels between the AF and SR groups at Site_1, Site_3, and Site_M (mean of the three sites) ( P < 0.05), while Site_2 showed non-significant but near-significant differences ( Figure 3G ).