The three-way subdivision of the population resulted in small group sizes and, as a result, some near-significant results (such as TT4 and SDMA at baseline) may represent real biological differences that could not be demonstrated owing to the study being statistically underpowered.
Contrasting “butanol versus baseline” yielded significant clusters in the amygdala, insula, the OFC, and a near-significant cluster in the piriform cortex.
Near-significant differences were observed according to the level of dyspnea.
Whereas, the L allele in rs1421811 LD block drove a near-significant increase of NPR3 expression and elevated cell proliferation, but not migration ( Supplementary Material, Fig.
It is noteworthy, however, that a near-significant interaction between group and hemisphere was found for the ILF and the FST ( P FDR = 0.09 and P FDR = 0.08, respectively).
Receiving auditory feedback was associated with a near-significant 15% increase in correct breath counting, suggesting improved state mindfulness.
Despite our small sample sizes, significant or near-significant differences distinguish each form of MT: TKIs-induced MT is characterized by more individual elongated eyelashes, higher number of UL eyelashes rows, and eyelash curvature; PGs-induced MT had higher proportion of poliosis.
Although we found a near-significant correlation between hippocampal MD and memory within the MCI group, it was substantially attenuated after including hippocampal volume as a covariate.
Post hoc power analysis showed effect sizes (dz) of around 0.40 for near-significant findings, suggesting at least 43 subjects are needed to detect small effects statistically.
An additional near-significant component was found (p corrected = 0.055) which described activity in the premotor areas.
The mean failure rates were relatively similar, with 4.92+-2.25 and 5.75+-2.26 for APOE genotypes ε3-ε3 and ε3-ε4, respectively. Near-significant group differences were found between ε3-ε3 and ε3-ε4 APOE groups for orientation tests and the overall number of test failures.
It can be seen that the initial fast growth rate provides a near-significant difference between the two groups of patients, in contrast to the other predictors, suggesting that this predictor may be a candidate for prediction of TTP.
IFN-γ levels showed a near-significant difference between groups (F (3,20) = 2.60, P adj = 0.082; Fig. 2c ), but no statistically significant differences were found ( P adj > 0.05).
Nonetheless, the results of the Cox regressions and survival curves remained the same ( for BMI>40 and MACCE, the significant effect turned into a near-significant effect, which we assume is because of its relatively small sample size compared to other groups).
A strong positive correlation was observed between seminal NA levels and the FSH/LH ratio, with seminal NA also showing a near-significant correlation with LH.
Conclusion One month after high-dose vitamin A supplementation, serum retinol concentrations did not increase significantly; however, the RID technique showed near-significant increases in TBS and TLR.
Three differentially expressed transcripts (i.e., ppp1r9a , gal3st1a , f5 ) were located in close proximity (± 120 kbp) to near-significant SNPs from the GWAS.
Diabetes mellitus, a known immune disorder, was also a near-significant risk factor for adverse effects after the first dose.
The results revealed a near-significant difference between the treatment and control groups in the SOFA score change at day 4.
The results of the ANCOVA analysis revealed a near-significant difference in terms of Hcy between the study groups after the adjustment of covariates [ Table 3 ].
Analysis of the separate segments of the dendritic tree revealed a significant increase in dendritic length in the middle segment in stressed rats accompanied by a near-significant increase at the distal segment ( Fig. 7 D).
In the regression models, the only near-significant relationship was between TUG testing and falls within the past 6 months.
Quantitative real-time PCR analysis showed (i) significant increases in the expressions of GRIA2 (GluA2 or AMPA receptor 2), SLC1A2 (EAAT2), SLC1A3 (EAAT1), (ii) a near-significant decrease in the expression of SLC7A11 (cystine-glutamate antiporter xCT) and (iii) a remarkable increase in GLUL expression (glutamine synthetase) in these cells compared to adult primary human microglia.
25 A significant and near-significant downregulation of Pax6os1 in pancreatic islets could be observed after 4 weeks of treatment with ASOs in female and male mice, respectively ( Figure S5 related to Figure 3 ).
In addition, near-significant associations with HIV infection were observed for resistance to isoniazid (OR 1.50, 95% confidence interval [CI] 0.99–2.26) and resistance to rifampin (OR 2.35, 95% CI 0.82–6.24) ( Table 1 ).