Barely Significant
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“near-significant”

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Listed by Otte et al. (2022)

In the literature

Previous cohort studies have reported a statistically significant decreasing trend with greater alcohol intake among drinkers for diffuse large B-cell lymphoma ( Lim et al , 2007 ; Troy et al , 2010 ), and no significant trend for Hodgkin lymphoma, follicular lymphoma, plasma cell neoplasms or any other non-Hodgkin subtype examined ( Lim et al , 2007 ; Kanda et al , 2010 ; Troy et al , 2010 ), although one study found a near-significant decreasing trend for plasma cell neoplasms ( Troy et al , 2010 ); comparable results from case–control studies were generally consistent with these findings ( Morton et al , 2005b ; Besson et al , 2006a , 2006b ).
For SNPs with significant allele and interaction coefficients, a meaningful allele main effect was considered present if the single-condition vehicle and ATRA analyses showed the same allelic direction of effect, with a vehicle Pemp < 0.1 and ATRA FDR < 0.1 (i.e., near-significant within each condition of n = 6, thus reasonably capable of achieving significance in the LMM analysis of the two conditions combined).