Dose–response relationships between essential minerals and pancreatic disease risk A significant overall association was observed between iodine levels and pancreatic cancer risk ( p < 0.001) with a near-significant non-linear trend ( p for non-linearity = 0.060), suggesting a continuous increase in risk with increasing iodine concentrations.
However, from the regression results on the occupation factor, retirement status demonstrates a near-significant correlation with subway travel.
However, the lack of significance in MRT change at the first week and the near-significant difference in CRT values during the first week may suggest a slower onset of the SC-DEX implant’s effect.
We examined these same subpopulations with respect to low (<10 km/h), medium (10–13 km/h), and high (≥13 km/h) maximum wind speeds, and identified a near-significant increased odds of lung infection in months of high wind speed ( table 4 ).
This near-significant negative coefficient suggests that AF may decrease PU, particularly in females, with each unit increase leading to a decrease of 0.13 in PU.
IL-8 showed near-significant reduction and no major changes in the T helper 2 cytokine IL-13 ( Fig. 5Q ).
Mid pregnancy 8-OHG levels showed a near-significant association with FSIQ scores ( P FDR = 0.05) (Additional file1: Table S8).
In the present study, 10 miRNAs demonstrating a significant or near-significant difference in expression between the metastasizing and non-metastasizing tumors were selected to undergo validation in our LAC cohorts by RT-qPCR.
Crosses exhibiting heterosis tended to be significant or near-significant across SAM traits ( Figure S2 ).
For the gene list downregulated in T1D subjects, there was a near-significant enrichment (EASE score<0.06) of terms related to cell migration/motility , cytokine binding, MHC class II receptor activity, chemokine receptor activity , chemokine receptor & MHC Class II, alpha chain .
Contrary however to the ascribed role of IEC-HuR in intestinal regeneration ( 16 , 18 ), IEC-HuRko mice mounted a stronger crypt hyperplastic counter-response maintained even till day 25, which was associated with a near-significant upregulation in crypt proliferation as assessed via Ki67 immunostainings during the peak of the disease at day 12 (Figures 3A,C,D ).
The comparison with the propensity score-match cohort washed away several significant or near-significant findings from the comparison with all non-BHI-grantee comparison.
Various other structure prediction methods at the genesilico.pl metaserver site [25] concurred and produced top-ranked fold matches to PA14 with near-significant scores.
Analyses of sensitivity revealed a near-significant difference between conditions in experiment 1, where people appeared least able to discriminate pairs in the mixed condition.
This was seen for all subjects and all tested production rates (1–1.66 Hz; except for one instance in subject C where the effect was near-significant).
While we found a near-significant difference in pieces of equipment for toddlers by site type (with centers having more pieces of activity promoting and fewer pieces of sedentary-promoting equipment than FCCH), it is unlikely that equipment alone resulted in the difference in active play that we observed across by site type.
Near-significant tobacco associations likely reflect the selected high-risk cohort, where cumulative exposure homogenizes the risk [ 18 ].
For ECR, neither condition nor time nor their interaction reached significance, while ECU and FCR demonstrated small but significant or near-significant temporal trends that were largely shared by both limbs, and FCU remained stable throughout.
Effects of participant sex in our study were also in the same direction as those in O'Gorman et al.'s study: they found a near-significant tendency for women to express more sympathy for the group member in the helping scenario (this was significant in our study, as was desire to help), but in neither study did participant sex have effects on anger towards the transgressor or contributions to help.
Patient-Report Outcomes Measurement Information System symptom scores moderated these relationships at significant or near-significant levels.
However, the difference in PFS as assessed by central radiology review was only near-significant, although numerically substantial.
The relatively small number of studies also restricts statistical power, limiting the ability to detect smaller yet clinically important differences – a limitation exemplified by the near-significant findings observed for dural tear incidence.
Conclusion Higher CCD improves DMFS in LA-NPC patients with IMRT, with a near-significant OS trend.
What is more, pentosidine concentration exhibited a near-significant tendency to be lower in the serum samples of the SLE patients.
Transcripts of LOC_Os01g03720 were positively correlated with the expression of miR164d (Figure 5C ), whereas the expression level of LOC_Os02g36880 was negatively correlated (at near-significant levels) with miR164d (Figure 5D ).