Among LI participants, and consistent with previous reports, 32 , 34 near-misses evoked significant or near-significant positive BOLD responses within the ventral striatum (t(23)=1.7438, P =0.0945), putamen (t(23)=2.0959, P =0.0473) and amygdala (t(23)=2.89, P =0.0083) (see Figure 3 ).
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Progression-Free Survival and Workflow Variables: The progression-free survival (PFS) patterns paralleled those observed for OS: median PFS was not reached in patients without pre-biopsy corticosteroid exposure, whereas patients who received steroids had a median PFS of 10.5 months, with a near-significant difference observed in log-rank testing ( p = 0.095).
These values were significantly higher than those at the 30 min time point ( p < 0.01), and linalyl acetate in the 10% group showed a near-significant difference compared to the 5% group at 60 min ( p = 0.095).
Temperature and humidity interacted as near-significant predictors of harmful response behaviour ( X 2 = 2.790, p = 0.095; individually temperature X 2 = 5.595, p = 0.018; humidity X 2 = 4.913, p = 0.027); there was a weak non-significant positive correlation between temperature and response ( t = 1.214, d.f. = 383, p = 0.226, r = 0.062) and a non-significant weak negative correlation between humidity and response ( t = −0.946, d.f. = 383, p = 0.345, r = −0.050).
The overall AEFIs reporting rate did not increase significantly after the adjustment (RR = 0.95, 95%CI : 0.83–1.08, P = .442), but notable dose-specific heterogeneity was observed: a near-significant increase for the first dose (RR = 1.67, P = .096), significant decreases for the second and third doses (RR = 0.70 and 0.40, respectively), and a substantially higher rate for the newly added fifth dose (684.84 per 100,000 doses).
In comparison with the placebo, ashwagandha supplementation was associated with a statistically significant reduction in the HAM-A ( P = .040) and a near-significant reduction in the DASS-21 ( P = .096).
Chao1 (83.75–478.96) and Shannon (1.24–6.15) indices showed near-significant differences (Kruskal–Wallis, Chao1: p = 0.097; Shannon: p = 0.051), suggesting interactive effects of season, region, and root type.
While opioid use demonstrated a near-significant interaction effect ( P = 0.097), further research is needed to clarify its role.
With M WT mice, 0.75 Gy GCRsim caused a near-significant reduction in levels of IL-10 compared to 0.5 Gy and sham-irradiated mice ( Figure 8 I, p = 0.0976, p = 0.0508, respectively), whereas levels were more consistent across doses of gamma ( Figure 8 J).
We also found a near-significant negative trend between aggressiveness in the wild (simulated conspecific intrusions) and HRS when analyzing both species together ( n = 20, r = − 0.4, p = 0.098) (Fig.
Exposure to Pb 2+ also resulted in a near-significant reduction in the number of vesicles in the RRP/docked vesicles in Perforant Path terminals ( p = 0.0989; Table 1 , IA) .
Of the four emotion themes, we found a near-significant effect of moving/bittersweet on pain unpleasantness ratings [MD = −3.61, t (482) = −1.65, p = 0.099].
A near-significant association was also observed between miR-133a and HDL-C (β = −0.213, P = 0.099).
The same protein displayed near-significant ( p = 0.099) enrichment in the Olfm4-H subset in healthy individuals.
As a supplement, the kappa index showed near-significant decrease from the wakefulness to the postprandial somnolence ( Figure S4 A, p = 0.0991, Cohen’s d = 0.1903).
For both multivariate logistic regressions, we retained significant or near-significant univariate predictors ( p < .10), and we forced the following variables into the model: age, food insecurity, and number of children.
Notable near-significant differences (0.05 < p < 0.1) are indicated in the figures.
Deep GM SANDI metrics that showed near-significant differences, defined as unadjusted P < 0.10, were compared for each deep GM region (averaged between the two hemisphere) between people with MS and HC.
Notable near-significant p values (0.05 < p < 0.1) are additionally specified in the figures.
Multivariable Cox regression models were constructed adjusting for variables with significant and near-significant p -values on univariable analysis ( p ≤ .1) and were performed for both the whole cohort and stratified by era.
Overall, 14 variables had significant or near-significant association ( p ≤ 0.1) with low resilience ( Table 2 ).
Differences in smoking status and alcohol consumption (both were used less during the pandemic) reached near-significant values ( p = 0.1 and 0.06, respectively).
Interaction models that slightly improved model fit (i.e., lower AIC) and included statistically significant (p < 0.05) or near-significant (p < 0.10) interaction terms were reported in place of the main effects model.
The values are only given for the significant (p < 0.05, black) and near-significant (p < 0.10, grey) slopes shown in Figures 2 and 3 .
Associations between disease duration and genus-level abundance were also evident, with significant ( p < 0.05) or near-significant ( p < 0.10) differences in 6 of the top 21 genera, including Propionibacterium , Salmonella , and Enterobacter (Fig. 2 b; Additional file 4 : Table S4).