“near-significant”

Hemoglobin level possessed a near-significant non-zero coefficient ( P = .09).

For Q5, a near-significant group effect was observed ( P =.09), with higher scores in the CTC12 and square dance groups than in the control group.

There was a near-significant difference for the younger groups, t (64) = 1.72, p = 0.09 (95%CI of this difference [−0.02, 0.26]), but not the older groups, t (56) = 0.78, p = 0.44 (95%CI of this difference [−0.14, 0.06]).

However, after heat shock (“Post”) all three lines showed a significant (2020-2-1, 2020-5-1, p < 0.05) or near-significant (2020-20-02, p ~ 0.09) increase in NAM-B1 above the baseline expression before treatment.

In that regard, although I agree with most of the Reviewer's suggestions, I must disagree with the one regarding the interpretation of near-significant results(Table 2, p=0,09).

One study reported a near-significant hazard ratio ( p = 0.09) that disfavored SRS over WBRT by a 68% higher rate of distant recurrence [ 18 ].

We found a near-significant main effect of training (p = 0.09) and a post-hoc test revealed that Nrf2 was significantly upregulated only in the GRS condition after exercise training (p = 0.03, pre compared to post) but not in the PLA condition (p = 0.83, pre compared to post, Sidaks post-hoc test).

The near-significant trends in other genera ( Akkermansia with p =0.09) also suggest the possibility of subtle but biologically relevant effects that may require further study.

Davies' test identified a near-significant T ewl of 34.7°C in Victorin's warbler ( P = 0.09).

Considering the near-significant differences in C-index between Node-RADS-integrated and cN-integrated prognostic models ( p = 0.091 and 0.053), we subsequently conducted NRI and IDI analyses.

The near-significant association with the college name (p=0.091) suggests institutional differences in how anesthesiology is perceived and taught.

In the MTX subgroup, both sides declined over time, with a significant left-sided decrease (25.40 ± 9.86% to 12.80 ± 6.94%, p = 0.043) and a near-significant right-sided decrease ( p = 0.091) ( Figure 4 , Table 4 ).

As a group, healthy controls had significant (PMC p < 0.007) 24-h rhythms in heart rate and diastolic blood pressure, and near-significant (PMC p < 0.091) rhythms in temperature and systolic blood pressure ( Figure 2 and Table 2 ).

A near-significant negative association was observed between sinus width bias (SW_bias) and lateral wall angle bias (A_bias) (r = −0.313, p = 0.092).

Although not statistically significant, the near-significant difference in Schirmer test pairwise values at 1 week ( p = 0.092) suggests a potential trend that may be clinically relevant if confirmed in larger studies.

“Follows commands” featured a near-significant association [odds ratio (OR) 0.55, 95% CI 0.27–1.10, p = 0.092]. “Follows commands” was kept in the model, since it substantially improved the model fit (Nagelkerke's R 2 from 0.32 to 0.34) ( Figure 2B ).

Pair-wise post hoc tests revealed no significant differences between the three detection protocols for RNA templates, although there was a near-significant tendency for RT-qPCR to be more affected by mismatches than RT-ddPCR and RT-qPCR dd-kit ( p = 0.092 and 0.090, respectively).

The association between GLP-1 receptor agonists and osteoporosis with pathological fractures was significant in the IVW analysis, yet the Q test in MR Egger regression indicated near-significant heterogeneity (p-value = 0.092489) ( Table 4 ), suggesting potential heterogeneity among instrumental variables for this association.

Importantly, Internet access had a large and near-significant effect ( β = 0.503, p = 0.093), likely reflecting improved access to health information or support networks.

There was also a near-significant two-way interaction between symmetry and character type ( F (3,360) = 2.15, p = 0.093).

Skin conductance response We observed a near-significant difference in SCR conditioning between the easy and difficult condition (stimulus × condition; F (1, 32) = 2.99, p < 0.094, η p 2 = 0 . 09 ) (Figure 2B ).

The near-significant trend observed for XDH ( p = 0.094) might indicate a weak endogenous rhythm, consistent with its antioxidative role and earlier studies describing partial circadian control of redox enzymes such as superoxide dismutase, catalase, and glutathione peroxidase [ 9 , 65 , 67 ].

While severe COVID-19 status showed a near-significant effect on creatinine and GFR ( p = 0.094 and p = 0.069, respectively), ICU admission significantly impacted GFR, ALT, and AST levels ( p = 0.010, p < 0.001, and p < 0.001, respectively).

The post hoc testing of the main effect of ACoA status demonstrated a near-significant difference between the control participants and the hazardous ACoA group (mean difference = 2.568, q(125) = 2.994, p = 0.094).

However, cytological findings showed a near-significant difference between men and women (χ2 (2) = 3.56, P = 0.094, calculated using Fisher’s exact test).